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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
31

Prevalence and control of strongyle nematode infections of horses in Sweden /

Osterman Lind, Eva, January 2005 (has links) (PDF)
Diss. (sammanfattning) Uppsala : Sveriges lantbruksuniversitet, 2005. / Härtill 5 uppsatser.
32

Biotransformace fenbendazolu v sóji (Glycine max) / Biotranformation of fenbendazole in soya (Glycine max)

Martínková, Lenka January 2019 (has links)
Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Bc. Lenka Martínková Supervisor: RNDr. Lucie Raisová Stuchlíková, Ph.D. Title of diploma thesis: Biotransformation of fenbedazole in soya (Glycine max) Veterinary drugs are used in large amounts in modern husbandry for treatment and prevention of diseases in animals. Anthelmintics administered to animals enter into environment primarily through its excretion in faeces or urine. Following excretion, drugs may persist in the environment and impact non-target organisms. Plants are able to uptake xenobiotics, including drugs, and detoxify them via biotransformation. However, only drug biotransformation into non-toxic and stable metabolites and their consequent accumulation in plants represent drug detoxification. For that reasons, knowledge of biotransformation pathways of drug in plants is very important. Soybean plants, eventually seeds, are further used in agriculture as feed for cattle and absorbed anthelmintics including their metabolites can enter the food chain. The results showed that fenbendazole entered plant and enzymatic systems of plant were able to biotransform fenbendazole via several reactions. We found differences in the metabolites between the roots, leaves, seeds and pods of soybean.
33

A comparison of laboratory and field resistance to macrocyclic lactones in Haemonchus contortus /

Galazzo, Daniel January 2004 (has links)
No description available.
34

Mechanisms of anthelmintic resistance in Cooperia oncophora, a nematode parasite of cattle

Njue, Annette Igandu January 2003 (has links)
No description available.
35

Pharmacokinetics of propylthio-benzimidazole anthelmintics : modulation of liver biotransformation in sheep and cattle

Lanusse, Carlos Edmundo January 1991 (has links)
No description available.
36

Genomic organization and expression of an avermectin receptor subunit from Haemonchus contortus

Liu, Jie, 1970- January 2003 (has links)
No description available.
37

Vliv anthelmintik na transport léčiv ve střevě / Effect of anthelmintics on the transport of drugs in the intestine

Štefanová, Anna January 2021 (has links)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Student: Bc. Anna Štefanová Supervisor: PharmDr. Ivan Vokřál, Ph.D. Title of diploma thesis: Effect of anthelmintics on the transport of drugs in the intestine Several classes of drugs are currently available for the treatment of helminthiasis in humans and animals, the so-called anthelmintics. Most of these drugs are administered by the oral route, where absorption into the systemic circulation occurs through the intestinal barrier. However, the course and extent of this absorption may be limited by biotransforming enzymes and transport proteins, in particular the family of so-called ATP-binding cassette transporters. These transporters are capable of returning many xenobiotics, including many drugs, back into the lumen of the gut and are the first line of defence against the entry of these substances into the body. An important representative of this group of transporters is P-glycoprotein, which is known for its broad substrate specificity. On this transporter, drugs can act as substrates but also as inhibitors and/or inducers, which may lead to the risk of drug-drug interactions. There is relatively little information about the effect of anthelmintics on P-glycoprotein inhibition. The most studied...
38

Development of DNA assays for the detection of single nucleotide polymorphism associated with benzimidazole resistance, in human soil-transmitted helminths

Diawara, Aïssatou. January 1900 (has links)
Thesis (M.Sc.). / Written for the Institute of Parasitology. Title from title page of PDF (viewed 2008/07/29). Includes bibliographical references.
39

Development of DNA assays for the detection of single nucleotide polymorphism associated with benzimidazole resistance, in human soil-transmitted helminths /

Diawara, Aïssatou. January 1900 (has links)
Thesis (M.Sc.). / Written for the Institute of Parasitology. Title from title page of PDF (viewed 2008/07/29). Includes bibliographical references.
40

Pharmacokinetic analysis of antimicrobials and an anthelmintic agent in alpacas and llamas with theoretical applications

Wattananat, Triporn 01 December 2003 (has links)
The pharmacokinetics of two antimicrobials were investigated in alpacas. Six healthy alpacas were each administered a single dose of 10 mg/kg of oxytetracycline by IV injection and IM injection. In addition, a single dose of 20 mg/kg of florfenicol by IV administration was given to alpacas in a separate study. The pharmacokinetic parameters of oxytetracycline and florfenicol in alpacas were compared to the results previously obtained in llamas. There were significant differences between llamas and alpacas in several of oxytetracycline pharmacokinetic parameters but there were no significant differences in all of florfenicol pharmacokinetic parameters in these two animals. It can be concluded that llamas and alpacas have different oxytetracycline disposition kinetics while they have similar disposition kinetics of florfenicol. The pharmacokinetics of clorsulon, a narrow-spectrum anthelmintic agent, was investigated in llamas following oral administration at a single dose of 14 mg/kg. The plasma levels of clorsulon produced by this dose was lower than the values reported in the clorsulon pharmacokinetic studies carried out in sheep and goats following oral administration at a single dose of 7 mg/kg This suggests the entire dose of clorsulon is not absorbed in llamas. Since the differential equations describing one-compartment system with first-order input and two-compartment system after IV administration with nonlinear elimination kinetics cannot be solved, there is no mathematical expression for the AUC for drugs following these models. The AUC values calculated from the proposed preliminary AUC equations for drugs following these models were compared to the AUC calculated using the trapezoidal rule method based on computer-generated data using the fourth-order Runge-Kutta method. Except for a few exceptions, the predicted AUC from the proposed equations matched the values calculated from the theoretically generated data. / Graduation date: 2004

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