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AH Automation har fått i uppdrag från Dahréntråd AB att genomföra en förstudie och ta fram ett automationskoncept för automatisk hantering av spolar runt en spoltvätt. Dahréntråd har för avsikt att upphandla en ny spoltävtt. Detta examensarbete är genomfört med avsikten att genomföra denna förstudie för AH Automation med målsättningen att det leder till ett effektivt system för automatisk hantering runt tvätten. Resultatet i denna rapport är ett koncept och kräver ytterligare arbete innan projektet kan realiseras. Många timmar arbete har spenderats på rundvandringar, diskussioner, möten, analys och ”trial & error” iteration framtagning. Detta har lett fram till en helautomatiserad lösning. Resultatet innefattar en robot som lastar in spolar i tvätten och en robot på en linjärenhet som lastar spolar från tvätten. Roboten innan spoltvätten sorterar pallar och mellanlägg samtidigt som den förser roboten efter tvätten med pallar och mellanlägg. Båda robotarna är utrustade med ett vakuumgripdon som har för avsikt att kunna hantera samtliga spole modeller, pallar och mellanlägg. Konceptet tillåter att spolar kan plockas manuellt när packningen inte är kompatibel med robotplock. Resultatet presenteras som en 3D layout skapad i Inventor Autodesk. / AH Automation has been commissioned by Dahréntråd AB to carry out a pilot study and develop an automation concept for automatic handling of bobbins around an industrial bobbin washer. Dahréntråd intends to buy a new bobbin washing machine. This thesis report is made with the intention of carrying out this pilot study for AH Automation with the aim that it leads to a effective automation system. The result in this report is a concept and requires further work before the project can be realized. Many hours of work have been spent on tours, discussions, meeting, analysis and trial & error iteration development. These steps have led to a fully automated solution. The result includes a robot that loads bobbins into the washing machine and one robot on a linear unit, that unloads the bobbins from the washing machine. The first robot is sorting pallets and slipsheets at the same time as it supplies the other robot with pallets and slipsheets. Both robots are equipped with a vacuum gripper that aims to handle all bobbin models, pallets and slipsheets. This concept also allows bobbins to be picked manually with lifting assistance when the bobbins are packed in such a way that that the robot can’t handle it.

<p>Ionizing radiation is used to screen for, diagnose, and treat breast cancer. Noncancerous breast cells are exposed to a range of doses as a result of these procedures in addition to the low levels of natural background radiation that they are always exposed to. With the consistent increase in medical radiation procedures, and the climbing rates of breast cancer in most populations, understanding the effects of these exposures is of interest and importance. Radiation exposure results in DNA double strand breaks which can trigger various cellular responses including cell cycle arrest, and cell death. Apoptosis is a form of highly regulated cell death that is controlled by the Bcl-2 family of proteins. Bcl-2 and Bcl-XL are anti-apoptotic proteins that are commonly overexpressed in human cancers including breast cancer. This thesis was focused on investigating the effects of Bcl-2 and Bcl-XL expression on the radiation response of human mammary epithelial cells. Bcl-2 and Bcl-XL were exogenously expressed in MCF-10A cells, and Bcl-XL expression was knocked down. Cytogenetic techniques were used to characterize the MCF-10A cells used. Automated image based assays were used to validate the anti-apoptotic effects of the exogenous proteins against known apoptotic stimuli, and to probe the effects of radiation exposure. The influence of Bcl-2 and Bcl-XL expression on the immediate and short term effects of radiation exposure was investigated using cell growth assays, flow cytometry, and</p> / Doctor of Philosophy (PhD)

Reconfigurable computing has the potential for providing significant performance increases to a number of computing applications. However, realizing these benefits requires digital design experience and knowledge of hardware description languages (HDLs). While a number of tools have focused on translation of high-level languages (HLLs) to HDLs, the tools do not always create optimized digital designs that are competitive with hand-coded solutions. This work describes an automatic optimization in the C-to-HDL transformation that reorganizes operations between pipeline stages in order to reduce critical path lengths. The effects of this optimization are examined on the MD5, SHA-1, and Smith-Waterman algorithms. Results show that the optimization results in performance gains of 13%-37% and that the automatically-generated implementations perform comparably to hand-coded implementations.

Digitization has fundamentally changed businesses, segments of society, and individuals’ life. There are two changing perspectives in the history of digital transformation. One is the expanding boundary of digitization, from a transformation within organizations, through innovations in interactions among businesses and customers, to societal changes at large. The other is the shifting focus of digitization, from digitizing production and delivery of goods and services, to digitizing all aspects of everyday life. However, extant research in digitization has not paid much attention to its impacts beyond the organizational boundary and the business relationships, and often adopted a technology-deterministic view of digitization. In this dissertation, I propose the notion, “digital citizenship”, to reexamine the nature and impact of digitization from a human-centric perspective and embed digitization in a broader social context. To elaborate on the notion of digital citizenship, I study the informative, automate, and transformative roles of digitization, and why and how various types of digitization enhance overall welfare for all parties of digital citizens. These three studies, presented as separate essays herein, i) evaluate the effectiveness of Intelligent Transportation Systems adopted by local governments transforming urban traffic management, ii) explore enhancing drivers’ traffic safety effort due to the deterrent potential of automated surveillance technology on the road, and iii) examine the mechanisms of information provision on customers decision making on churn and the implications for firms on the challenge of digital channel attribution. In regard to each, I discuss the relevant theory, the methodology, data sources, results, and implications. I conclude by highlighting the contributions of my work, and possible avenues for future research. / Business Administration/Management Information Systems