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Bacterial attachment and activity in oligotrophic environmentsGammack, Graham F. January 1988 (has links)
No description available.
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Investigation of biofilms in copper tube corrosion and the survival of Legionella pneumophila on alternative plumbing materialsWalker, James January 1994 (has links)
An unusual form of copper tube corrosion, occurring in two hospitals, was investigated during two site surveys and due to the presence of characteristic perforations became known as pepper-pot pitting corrosion. The corrosion was found to occur predominantly in soft water areas but mainly in hot water systems maintained below 50'C. When monitoring the hot water system at a particular site the water temperature was found to decrease overnight with a corresponding decrease in the dissolved oxygen concentration and assimilable organic carbon. Copious amounts of biofilrn were recovered from the pipe surfaces thus it was hypothesised that metabolically active and respiring biofilm bacteria contributed to the creation of aggressive corrosive conditions at the copper tube surface. At control sites where this type of corrosion was not reported, the water temperature was found to be maintained above 50'C with reduced biofouling. A laboratory model, using filter-sterilised potable water as the sole carbon source, was developed to investigate the conditions under which corrosion and biofouling was occurring. Biofilm development was demonstrated up to 55'C. At 60"C biofouling was very much reduced; however, a decrease in the number of bacteria recovered from the planktonic phase was only observed at 65'C. Planktonic bacteria were found to be dominated by pseudomonads while the biofilm was dominated by other Gram negative bacteria. Control measures that would slow down or prevent corrosion were studied. Pasteurisation (60'C) was found to prevent biofouling as well as controlling re-established biofilms but was less effective against consortia that had been previously exposed to this temperature. For the removal and control of biofilm, sulphamic acid was more effective than citric acid which allowed re-growth to occur within 14 days. This unusual copper tube corrosion has resulted in increased use of alternative plumbing tube materials and therefore colonisation of copper and competitive plastic materials were investigated in the model system. Plastic materials were shown to encourage growth of Legionella pneumophila at 40'C whereas copper suppressed the growth of this water-borne pathogen. Results obtained in this investigation suggest that plastic plumbing systems pose a potential health risk by providing a means for transmission of pathogens such as L. pneumophila. The association of biofilms with pepper pot pitting led to new ideas about mechanisms of microbially induced corrosion of copper tubing. A number of techniques including SEM, SCLM and light microscopy were used to demonstrate the heterogeneity and metabolic activity of biofilms produced in the laboratory model and on pipe surfaces. Mosaic microcolonies, themselves are responsible for the initiation of differential concentration sites that are aggravated by exo-polysaccharides, metabolic activity and particulate matter in the aquatic environment. It is the localised distribution of initiated sites that could be responsible for the formation of multi-loci corrosion cells that are driven by an electrochemical potential forming the type of corrosion described as pepper-pot pitting.
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The influence of fluid dynamics and surface material on pure and binary culture biofilmsBrading, Melanie Gayle January 1996 (has links)
No description available.
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DISTRIBUTION OF METABOLIC CHARACTERISTICS AMONG AEROBIC SOIL BACTERIA AND IMPLICATIONS FOR BIOTRANSFORMATION OF ORGANIC AND METALLIC WASTESZhang, Fangmei January 2007 (has links)
No description available.
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Application of targeted molecular and material property optimization to bacterial attachment-resistant (Meth)acrylate polymersAdlington, K., Nguyen, N.T., Eaves, E., Yang, J., Chang, Chien-Yi, Li, J., Gower, A.L., Stimpson, A., Anderson, D.G., Langer, R., Davies, M.C., Hook, A.L., Williams, P., Alexander, M.R., Irvine, D.J. 2016 July 1926 (has links)
Yes / Developing medical devices that resist bacterial attachment and subsequent biofilm formation is highly desirable. In this paper, we report the optimization of the molecular structure and thus material properties of a range of (meth)acrylate copolymers which contain monomers reported to deliver bacterial resistance to surfaces. This optimization allows such monomers to be employed within novel coatings to reduce bacterial attachment to silicone urinary catheters. We show that the flexibility of copolymers can be tuned to match that of the silicone catheter substrate, by copolymerizing these polymers with a lower Tg monomer such that it passes the flexing fatigue tests as coatings upon catheters, that the homopolymers failed. Furthermore, the Tg values of the copolymers are shown to be readily estimated by the Fox equation. The bacterial resistance performance of these copolymers were typically found to be better than the neat silicone or a commercial silver containing hydrogel surface, when the monomer feed contained only 25 v% of the “hit” monomer. The method of initiation (either photo or thermal) was shown not to affect the bacterial resistance of the copolymers. Optimized synthesis conditions to ensure that the correct copolymer composition and to prevent the onset of gelation are detailed. / Impact Accelerators Account at the University of Nottingham; Camstent Ltd; The Wellcome Trust (ref 085245 and 103882)
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Fundamental Study of the Initial Bacterial Attachment of Pseudomas aeruginosa, Pseudomas putida and Escherichia coliRaya, Akhila 23 December 2009 (has links)
No description available.
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