Assessment of long term changes in levels of biogenic substances and their amount, with regard to water yield and intensity of anthropogenic activity, in the water of different hydrological areas of Lithuania. Comparative analysis of methods for calculation of biogenic substance flows. Establishment of possibility to reduce frequency of water sampling. ATV-DVWk water quality model was for the first time in Lithuania used for forecasting of the changes in the water quality in the longitudinal profile of a river. / Biogeninių medžiagų kaitos upių vandenyje tyrimai ir įvertinimas.