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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
21

The role of chloride in the volume regulation of human glioma cells

Ernest, Nola Jean. January 2007 (has links) (PDF)
Thesis (Ph. D.)--University of Alabama at Birmingham, 2007. / Title from first page of PDF file (viewed Oct. 30, 2007). Includes bibliographical references (p. 165-174).
22

The effects of copper depletion on intracerebral angiogenesis and growth of experimental brain tumors /

Zagzag, David. January 1988 (has links)
No description available.
23

The epidemiology, biology and genetics of human astrocytic tumours /

Bäcklund, Magnus, January 2005 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 4 uppsatser.
24

Loss of PIAS3 expression in glioblastoma multiforme tumors implications for STAT-3 activation and gene expression /

Brantley, Emily Claire. January 2007 (has links) (PDF)
Thesis (Ph. D.)--University of Alabama at Birmingham, 2007. / Title from first page of PDF file (viewed June 5, 2008). Includes bibliographical references.
25

Regulation of ongoing DNA synthesis in normal and neoplastic brain tissue /

Yakisich, Juan Sebastián, January 2005 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 6 uppsatser.
26

Neuroblastoma as a target for effector mechanisms of the immune system /

De Geer, Anna, January 2007 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 4 uppsatser.
27

Role of transient receptor potential canonical channels in glioma cell biology

Bomben, Valerie Christine. January 2010 (has links) (PDF)
Thesis (Ph.D.)--University of Alabama at Birmingham, 2010. / Title from PDF title page (viewed on June 25, 2010). Includes bibliographical references.
28

The expression and function of Wilms' tumor 1 in malignant Glioma /

Clark, Aaron J., January 2006 (has links)
Thesis (Ph. D.)--Virginia Commonwealth University, 2006. / Prepared for: Dept. of Anatomy and Neurobiology. Bibliography: leaves 151-202. Also available online.
29

Ressecação de lesões em area motora cortical e subcortical e avaliação quanto ao uso dos metodos auxiliares intraoperatorios / Resection of lesions in the cortical and subcortical motor area and evolution of the intraoperative auxiliary methods

Sarmento, Stenio Abrantes 10 August 2009 (has links)
Orientador: Helder Tedeschi / Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas / Made available in DSpace on 2018-08-14T16:36:45Z (GMT). No. of bitstreams: 1 Sarmento_StenioAbrantes_D.pdf: 8005225 bytes, checksum: 536dc762dc674f3a764c2acd713848f5 (MD5) Previous issue date: 2009 / Resumo: Nos últimos anos, consideráveis avanços tecnológicos, principalmente métodos de localização funcional do córtex cerebral, têm surgido no sentido de melhorar os resultados cirúrgicos no tratamento de lesões em áreas eloqüentes. O objetivo deste estudo é avaliar os resultados pós-operatórios em 74 pacientes submetidos à ressecção de lesões em área motora ou adjacente, utilizando-se de planejamento com exames de neuroimagem, conhecimento anatômico, técnica microcirúrgica adequada e métodos auxiliares a exemplo da estimulação intra-operatória. Glioma foi o diagnóstico histopatológico em 32 pacientes (43,2%), seguido de meningeoma em 19 pacientes (25,6%), metástase em 11 pacientes (14,8%) %), cavernoma em 5 (6,8%), linfoma primário em 02 pacientes, cisticercose em 2, displasia em 2 (2,7%) e processo inflamatório inespecífico em 1 paciente (1,4%). A ressecção cirúrgica foi considerada total em 68 (93,1%) pacientes e subtotal em 05 (6,84%). 54 pacientes (73,9%) apresentavam força muscular normal (grau 5) no préoperatório. Destes, 20 (37,3%) apresentaram déficit no pós-operatório imediato, sendo que 17 (85%) recuperaram completamente o déficit em até 3 meses e 3 pacientes apresentaram melhora parcial. 19 pacientes apresentavam déficit no pré-operatório. Destes, 05 apresentaram piora do déficit no pós-operatório imediato (sendo que 04 (80%) tiveram melhora no pós-operatório tardio) e 02 melhoraram já no pós- operatório imediato. A estimulação intra-operatória foi utilizada em 65% dos casos, principalmente nos gliomas, e, estereotaxia nos pacientes com cavernomas. Concluímos que a morbidade em pacientes operados de lesões em área motora é bastante aceitável e justifica a indicação cirúrgica com tentativa de ressecção máxima. As lesões extrínsecas (meningeomas e metástases) podem ser completamente ressecadas com baixa morbidade, sem nenhum método adicional, apenas conhecimento anatômico e técnica cirúrgica adequada. A estimulação intra-operatória foi fundamental para guiar a ressecção em grande parte dos gliomas. Não houve diferença na morbidade e nem no grau de ressecção quando comparamos os nossos resultados com aqueles da literatura em que usam métodos funcionais de imagem, neuronavegação ou outros métodos como a ressonância intraoperatória. Lesões subcorticais, como por exemplo, cavernomas podem ser tratadas utilizando apenas estereotaxia. / Abstract: In recent years considerable technological advances have been made with the purpose of improving the surgical results in the treatment of eloquent lesions. The overall aim of this study is to evaluate the postoperative surgical outcome in 74 patients who underwent surgery to remove lesions around the motor area, in which preoperative planning by using neuroimaging exams, anatomical study, appropriate microsurgery technique and auxiliary methods such as intraoperative stimulation were performed. Glioma was the histological diagnosis in thirty two patients (43,2%) follow by meningeoma in nineteen patients (25,6%), metastasis in eleven patients (14,8%), cavernoma in five (6,8%), primary linfoma in two patients, cisticercus in two, cortical dysplasia in two (2,7%) and inflammatory lesion in one patient (1,4%). Gross total removal was achieved in sixty-eight (93,1%) patients and subtotal in five (6,84%). Fifty-four patients (73,9%) presented a normal motor function in the preoperative period. Of these, twenty (37,3%) developed transitory deficit, nevertheless 85% of these presented a complete recovery later and three evolved with partial improvement. Nineteen patients presented a motor deficit preoperatively. Of these, five presented deterioration, but four patients improved later and two patients recovery in the early post-operative. The intraoperative stimulation was used in 65% of the patients, mainly in gliomas. Stereotaxy was used in patients with cavernoma. We concluded that the resection of lesions in motor areas is feasible. Lesions such as meningeomas and metastasis can be safely operated on without the necessity of auxiliary methods by using anatomic knowledge and appropriate surgical technique only. Intraoperative stimulation was very important to guide the resection in many cases of gliomas. There was no difference in the morbidity and resection grade when we compared our results with those who use image functional methods, neuronavegation system or other methods such as intraoperative magnetic resonance image in surgery around the motor area. Subcortical small lesions such as cavernoma can be treated by using stereotaxy techniques. / Doutorado / Neurologia / Doutor em Ciências Médicas
30

Identification and investigations of leucine-rich repeats and immunoglobulin-like domains protein 2 (LRIG2)

Holmlund, Camilla, January 2010 (has links)
Diss. (sammanfattning) Umeå : Umeå universitet, 2010.

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