Esta pesquisa avaliou o efeito de diferentes técnicas de limpeza aplicadas na superfície de esmalte intacto, na resistência adesiva de resina composta usando sistemas adesivos self etch. Coroas dentais foram cortadas e obtidos 90 fragmentos (n=10), cujas superfícies de esmalte permaneceram em contacto com saliva humana fresca por 1 hora, recebendo a seguir de acordo com o grupo, limpeza com uma das seguintes técnicas: pasta de pedra pomes/água seguida de detergente aniônico Tergensol (PP), jato de bicarbonato de sódio (B), ou spray ar/água (C). Após limpeza, um dos sistemas adesivos foi aplicado: Clearfil SE Bond (CF), Adper Prompt (AD) ou Scotchbond Multi-Purpose (SB), realizando-se um bloco de resina composta Z250 de 4 ou 5 mm sobre o adhesivo dental. Após 24 horas de armazenagem, os corpos de prova foram cortados em maquina Labcut, originando palitos com área adesiva de aproximadamente 1 mm 2 . Cada palito foi adaptado em um dispositivo de tração, para serem realizados os testes de resistência adesiva. A análise estadística, considerando a cada palito como unidade amostral, e os tipos de fraturas apresentadas, mostrou ausência de diferença entre os sistemas adesivos usados. Entre as técnicas de limpeza testadas, valores de RMT foram superiores para a técnica de PP, não se encontrando diferenças estatisticamente significantes entre B e C. A análise ao MEV da interface esmalte/resina confirmou os resultados estatísticos encontrados e permitiu observar que a interação resina adhesiva/esmalte ocorre de maneira diferente entre os sistemas self etch e all etch. Concluiu-se que, a técnica PP constitui uma opção adequada de limpeza de superfícies de esmalte liso intacto e que a técnica de bicarbonato pode afetar a resistência adesiva destas superfícies. / This study evaluated the effect of different cleaning techniques in the adhesive bond strength of self-etching bonding systems to unground enamel after being in contact with human saliva. Ninety enamel fragments were obtained from dental crowns (n = 10) and the enamel surface of each fragment were kept in contact with fresh human saliva for 1 hour. Next, they received the cleaning treatment according to the group as follows: pumice and water paste followed by anionic detergent - Tergensol (PP), sodium bicarbonate jet (B), or air/water spray (control group - C). After cleaning procedures, one of the bonding systems was applied: Clearfil SE Bond (CF), Adper Prompt (AD), or Scothbond Multi-Purpose (SB), and a Z250 composite resin bloc with 4 or 5 mm was built above the dental adhesive. After 24 hours of storage, the specimens were sectioned to obtain sticks with cross sectional areas of approximately 1 mm². The sticks were submitted to microtensile test in an Instron testing machine. Statistical analysis of the results, considering each stick as a sample unit and the fracture kinds presented, showed no statistical significant difference in mean shear bond strength among the bonding systems used. Regarding to the cleaning techniques, shear bond strength values were superior for PP and there was no significant statistical difference between B and C. The interface enamel/dentin SEM analysis corroborated the statistical results I was concluded that PP method is appropriate for cleaning unground enamel surface after salivary contact, improving bond strength of all etch and self etch adhesive systems, and that cleaning with sodium bicarbonate jet may affect the bonding strength of these surfaces.

O carcinoma epidermoide de cavidade oral (CECO) é um dos tumores mais comuns em câncer de cabeça e pescoço, com aproximadamente 300.000 novos casos e 145.000 mortes em todo o mundo. Apesar da intensa pesquisa e dos avanços recentes no diagnóstico e terapia, a taxa de sobrevivência dos pacientes ainda é baixa. Os estudos da metabolômica levaram a uma melhor compreensão do metabolismo do câncer, no seu desenvolvimento e progressão. Essas descobertas possibilitaram a identificação de biomarcadores metabólicos que podem auxiliar na identificação de doenças e tratamentos. O presente estudo buscou três objetivos: (1) Identificar e quantificar os metabólitos plasmáticos em portadores de CECO e em controles, utilizando técnicas de ressonância magnética nuclear (RMN); (2) Comparar a concentração plasmática de metabólitos de pacientes com CECO com a de seus controles estratificados por variáveis clínicas, patológicas, sociodemográficas e características de estilo de vida; (3) Avaliar se as concentrações de metabólitos estão relacionadas com a presença da doença (CECO), ajustadas pelas variáveis epidemiológicas e características de estilo de vida. Para a análise dos metabólitos, amostras de plasma sanguíneo de 47 casos e de 49 controles foram identificadas, quantificadas e comparadas com variáveis clínicas, patológicas, sociodemográficas e características de estilo de vida por meio de análises estatísticas. Os resultados mostram que todos os indivíduos portadores de CECO estiveram expostos em algum momento da vida aos fatores de risco (álcool, tabaco e má higiene bucal). Além disso, as variáveis mostraram interferir na concentração dos metabólitos, estes que apresentaram-se alterados, principalmente os que possuem relação com as vias metabólicas de obtenção de energia, sugerindo que o metabolismo de pacientes com CECO difere dos indivíduos sem a doença (controles) / Squamous cell carcinoma of the oral cavity (SCCOC) is one of the most common tumors in head and neck cancer, with approximately 300,000 new cases and 145,000 deaths worldwide each year. Despite intense research and recent advances in diagnosis and therapy, the patient\'s survival rate is still low. Metabolism studies have led to a better understanding of the metabolism of cancer in its development and progression. Theses findings allowed the identification of metabolic biomarkers that may aid to identificate diseases and treatments. This current study aimed at three objectives: (1) To identify and quantify plasma metabolites in SCCOC patients and controls using nuclear magnetic resonance (NMR) techniques; (2) To compare plasma concentration of metabolites of patients with SCCOC and its stratified controls by clinical, pathological, sociodemographics, and lifestyle characteristics; (3) To evaluate whether the metabolic concentrations are related to the presence of SCCOC, adjusted by epidemiological variables and lifestyle characteristics. In order to analyze the metabolites, blood plasma samples from 47 cases and 49 controls were identified, quantified and compared with clinical, pathological, sociodemographic, and lifestyle variables by means of statistical analysis. The results show that all subjects with SCCOC were exposed eventually to risk factors (alcohol consumption, smoking and bad oral hygiene). Furthermore, the variables showed to interfere in the concentration of metabolites, which have been altered, especially those that are related to metabolic pathways of obtaining energy, suggesting that the metabolism of patients with SCCOC differs from the individuals without the disease (controls)

O objetivo deste estudo foi avaliar a definição do ângulo cavossuperficial em preparos realizados com instrumentações rotatória e ultrassônica com o sistema CVDentUS utilizando potências variadas do aparelho de ultrassom. Quatro cavidades em forma de circunferência foram realizadas na face vestibular de 10 dentes incisivos bovinos, utilizando-se as pontas cilíndricas CVDentUS (n.82137) e diamantada convencional para alta rotação (n.1092). A amostra foi dividida em 4 grupos: G1 Alta rotação; G2 Ultrassom com potência de 30%; G3 Ultrassom com potência de 60%; G4 Ultrassom com potência de 90%. Os preparos realizados foram padronizados medindo aproximadamente 2 mm de diâmetro e 4 mm de profundidade. Os preparos foram examinados em MEV, o que possibilitou avaliar o ângulo cavossuperficial de cada preparo. Cada preparo foi registrado por meio de fotomoicrografias para serem analisados no programa computadorizado Image pró-plus, que permitiu quantificar a área irregular de cada preparo. Os resultados foram analisados com ANOVA (p< 0,00003), verificando-se a significância estatística entre os fatores, foi aplicado o teste de Tukey que demonstrou haver diferenças na área das irregularidades dos preparos avaliados. Com base na metodologia empregada pôde-se concluir que a definição do ângulo cavossuperficial sofre influência relativa em função do tipo de instrumentação, sendo que a instrumentação rotatóra demonstrou similaridade quanto a regularidade marginal dos preparos cavitários quando comparada com a instrumentação ultrassônica utilizada na faixa de 30% da potencia máxima do aparelho, no entanto quando utilizada nas outras potências avaliadas (60 e 90%) houve alterações mais significativas na definição marginal dos preparos cavitários / The aim of this study was to evaluated the definition of the cavosurface margin in cavity preparations made with a high speed dental handpieces (360.000 rpm) and with ultrasonic devices. Four cavities in the form of a circle were performed in a buccal surface of 10 bovine incisor teeth, using cylindrical tips CVDentUS (n.82137) for ultrasound and conventional cylindrical diamond bur (n.1092) for rotary instrumentation. The sample was divided into 4 groups: G1 - High speed, G2 - Ultrasound with power level of 30%, G3 - Ultrasound with power level of 60%, G4 - Ultrasound with power level of 90%. The preparations were standardized measuring approximately 2 mm in diameter and 4 mm in depth. The specimens were examined by SEM to evaluate the cavosurface margin of each preparation. The images were analyzed in a computer program, Image Pro-Plus 4.5, which allowed quantifying the irregular area of each preparation. The results were analyzed by ANOVA (p<0, 00003) showed statistically significant differences. The Tukey test pointed differences in the irregularities areas of the preparations. According to the methodology used, rotary instrumentation showed similarity, as the marginal regularity of dental cavities, compared to ultrasonic instrumentation used in the range of 30%. It was concluded that both instruments are effective for the realization of cavity preparations, however when the powers of 60 and 90% were used, cavity margins showed less defined.

Orientador: Gustavo Silva Wiederhecker / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Física Gleb Wataghin / Made available in DSpace on 2018-08-23T23:27:40Z (GMT). No. of bitstreams: 1 Luiz_GustavodeOliveira_M.pdf: 12840478 bytes, checksum: 50b184b19ca56624e14520e4331b112a (MD5) Previous issue date: 2013 / Resumo: A transferência de momento linear da luz para partículas foi teorizada no século XVII por Johanes Kepler e demonstrada pela primeira vez por Lebedev e, independentemente, por Nichols e Hull apenas em 1901. Em cavidades ópticas, como demonstrado por V. Braginsky, essa interação pode dar origem a diversos fenômenos interessantes. No ano de 2005 Tal Carmon demonstra alguns destes efeitos em cavidades microfabricadas. Nesta dissertação são apresentados os resultados de estudos sobre as microcavidades optomecânicas de disco duplo de nitreto de silício. Dentre estes estão medidas de ruído térmico de uma cavidade optomecânica deste tipo; a demonstração teórica de que deve ser possível operar tais cavidades no regime de banda lateral resolvida, usando modos mecânicos de ordem superior; a otimização do processo de fabricação destas cavidades, culminando em cavidades com fatores de qualidade mecânico, em vácuo e a temperatura ambiente, em torno de 10000 / Abstract: Momentum transfer from light to particles was theorized in the XVII century byJohanes Kepler and experimentally demonstrated for the first time by Lebedev and, independently, by Nichols and Hull only in 1901. In optical cavities, as shown by V. Braginsky, this interaction may result in many interesting phenomena. In 2005 Tal Carmon demonstrated some of these effects in microfabricated cavities. In this thesis the results of studies on silicon nitride double-disk optomechanical microcavities are presented. Among these results are the theoretical demonstration that it is possible to drive such devices in the resolved side-band regime, exciting higher order mechanical modes, thermal noise measurements and optimization of the fabrication process, yielding cavities with mechanical quality factors close to 10000, in vacuum and at room temperature / Mestrado / Física / Mestre em Física

La possibilité de reproduire une activité enzymatique de manière artificielle est l’un des objectifs de la chimie moderne mais reste un grand défi, même dans le cas de l’activation de petites molécules. Dans le cas du dihydrogène, certaines bactéries s’en servent comme vecteur d’énergie par l’intermédiaire d’enzymes appelées hydrogénases qui peuvent former ou consommer le dihydrogène grâce à des complexes à base de métaux non nobles. Le dihydrogène pouvant être également utilisé comme vecteur d’énergie dans nos sociétés, les hydrogénases font l’objet de nombreuses recherches. Jusqu’à présent, la plupart des complexes modèles d’hydrogénases se sont employés à modifier la première sphère de coordination pour reproduire au mieux ses propriétés électroniques. Néanmoins, l’étude de mutations ciblées des hydrogénases indique que plusieurs résidus d’acides aminés présents dans le site actif sont indispensables à la stabilité du complexe et à son efficacité catalytique, montrant ainsi comment le mime d’une deuxième sphère de coordination pourrait améliorer les propriétés des catalyseurs artificiels. Notre approche a consisté en l’utilisation de foldamères de type oligoamide aromatique, formant un cône autour d’un complexe modèle d’hydrogénase. La synthèse convergente du composé final, son étude structurale à l’état solide (diffraction des rayons X), en solution (RMN, IR) ainsi que sa dynamique ont été étudiées. La modification de la première sphère de coordination du complexe modèle en présence du foldamère est également décrite et montrant notamment leur interaction. / The ability to replicate enzymatic activity with a synthetic molecule is a highly sought after goal in modern chemistry. However, it remains a big challenge even in case of activation of small molecules. In the case of hydrogen, some bacteria can use it as energy carrier by means of enzymes called hydrogenases that can reversely make or break the bond of hydrogen molecules and are made of earth abundant metals. As hydrogen could be used for the same purpose of energy storage in our society, hydrogenases caught interest of scientific community. To date, most biomimetic hydrogenase models mainly focus on first coordination sphere modifications to fine-tune structure and physical properties. However, point mutation studies indicate that several of the amino acid residues surrounding the enzyme active site are required for structural stability or high turnover frequencies. It shows how mimicking second coordination sphere could improve the capabilities of synthetic catalysts. Our approach used aromatic oligoamide foldamers as helical scaffolds around an inspired 2Fe2S4cluster. Convergent synthesis of the final molecule and structural studies in the solid state (x-ray) and in solution (NMR, IR) as well as the dynamic behaviour are reported. Modifications of the first coordination sphere of the model complex in presence of the foldamer are also described, showing interactions between them.

Linear colliders are an option for lepton collision at several TeV. The Compact Linear Collider (CLIC) aims at electron and positron collisions at a centre of mass energy of 3 TeV. In CLIC, the main accelerating structures are designed to operate at an X-band frequency of 12 GHz with an accelerating gradient of 100 MV/m. Two significant issues in linear accelerators that can prevent high gradient being achieved are electrical breakdown and wakefields. The baseline design for the CLIC main linacs relies on a small aperture size to reduce the breakdown probability and a strong damping scheme to suppress the wakefields. The strong damping scheme may have a higher possibility of electrical breakdown. In this thesis an alternative design for the main accelerating structures of CLIC is studied and various aspects of this design are discussed. This design is known as a Damped and Detuned Structure (DDS) which relies on moderate damping and strong detuning of the higher order modes (HOMs). The broad idea of DDS is based upon the Next Linear Collider (NLC) design. The advantages of this design are: well damped wakefields, minimised rf breakdown probability and reduced size of the structure compared to the strong damping design. Procedures necessary to minimise the rf monopole fields and enhance the wakefield suppression are discussed. The rf as well as mechanical designs of a test structure are presented. This unique design forms the basis of this research and allows both the electrical breakdown and beam dynamics constraints to be simultaneously satisfied.

Cette thèse présente de nouveaux développements pour de petites antennes en cavité. L'objectif principal de la thèse est l'analyse de la performance de la bande passante de ces antennes pour des tailles d'ouverture qui sont petites par rapport à la longueur d'onde en espace libre. Des cavités de formes rectangulaires et circulaires intégrées dans un plan de masse infini et dans des plans de masse de dimensions latérales finies sont examinées en détail. Jusqu'à présent, dans la littérature, le choix pour ces antennes en cavités portait sur des antennes imprimées microruban (patch). L'objet de la thèse est de déterminer si les performances d'antennes en cavité de petite taille peuvent être améliorées et si oui, de quelle façon. A cet effet, nous avons tout d'abord étudié théoriquement, la limite supérieure de la bande passante pour cette configuration particulière en cavité. Nous en avons conclu que les antennes microruban intégrées dans une cavité n'atteignent pas la limite de la bande passante, ce qui est l'un des principaux résultats de la thèse. Les antennes intégrées dans une cavité avec un plan de masse infini ou fini sont ensuite analysées à l'aide de plusieurs modèles de ligne de transmission simples. Le deuxième résultat clé de la thèse un modèle de ligne de transmission spécifique et original qui montre que cette limite sur la bande passante est réellement atteignable. Par conséquent, ce modèle de ligne de transmission devient la base d'une nouvelle conception pour l'antenne en cavité. Enfin, le résultat le plus important de la thèse est la conception concrète de nouvelles antennes en cavité capables d'atteindre la performance maximale en bande passante. D'autres sujets sont abordés sont: i) la comparaison avec des structures à base d'éléments empilés en termes de bande passante, de facilité de fabrication et de coût, ii) l'extension de la limite grâce à l'inclusion de matériaux magnétiques idéaux et conducteurs magnétiques; iii) l'utilisation de la nouvelle structure d'antenne pour la constitution d'un réseau d'antennes compact; iv) les avantages de la nouvelle structure pour la réalisation d'antennes en cavité de tailles vraiment petites pour lesquelles les méthodes classiques ne permettent pas la réalisation d'antennes. / This thesis presents new developments in cavity type antennas. The main objective of the thesis is bandwidth performance analysis of antennas in cavities with aperture sizes which are small compared to the free space wavelength. Cavities of rectangular and circular shapes in an infinite and finite ground plane are investigated in detail. So far in the literature, microstrip patch antennas were the antenna of choice for cavity type antennas. The intention of the thesis is to determine if cavity type antennas can be improved and how. To this end, the bound on bandwidth for cavity antennas is investigated theoretically. It is concluded that patch antennas, in fact, do not reach the bound for cavity antennas, which is one of the key results of the thesis. Infinite and finite sized ground plane cavity antennas are further analyzed using several simple transmission line models. The second key result of the thesis is a demonstration that a special transmission line model corresponds to antennas that reach the bound on bandwidth. This transmission line model is the basis to a new cavity antenna design. Finally, the most important result is a practical, physical, design of novel cavity antennas capable of reaching the bandwidth bound. Furthermore, several additional topics are explored; i) A comparison with stacked patches design in terms of bandwidth, ease of fabrication, and cost; ii) The extension of the bound with the inclusion of ideal magnetic materials and magnetic conductors; iii) The new antenna design use in constructing a compact antenna array; iv) The benefits of the new design for constructing small cavity antennas previously not feasible with the classical design.

The mass and thermal transport in porous media play an important role in many engineering and geological processes. The hydrodynamic and thermal effects are two interesting aspects arising in the research of porous media. This thesis is concerned with numerical investigations of double-diffusive natural convective heat and mass transfer in saturated porous cavities with Soret and Dufour effects. An in-house FORTRAN code, named ALFARHANY, was developed for this study. The Darcy-Brinkman-Forchheimer (generalized) model with the Boussinesq approximation is used to solve the governing equations. In general, for high porosity (more than 0.6), Darcy law is not valid and the effects of inertia and viscosity force should be taken into account. Therefore, the generalized model is extremely suitable in describing all kinds of fluid flow in a porous medium. The numerical model adopted is based on the finite volume approach and the pressure velocity coupling is treated using the SIMPLE/SIMPLER algorithm as well as the alternating direction implicit (ADI) method was employed to solve the energy and species equations. Firstly, the model validation is accomplished through a comparison of the numerical solution with the reliable experimental, analytical/computational studies available in the literature. Additionally, transient conjugate natural convective heat transfer in two-dimensional porous square domain with finite wall thickness is investigated numerically. After that the effect of variable thermal conductivity and porosity investigated numerically for steady conjugate double-diffusive natural convective heat and mass transfer in two-dimensional variable porosity layer sandwiched between two walls. Then the work is extended to include the geometric effects. The results presented for two different studies (square and rectangular cavities) with the effect of inclination angle. Finally, the work is extended to include the Soret and Dufour effects on double-diffusive natural convection heat and mass transfer in a square porous cavity. In general, the results are presented over wide range of non-dimensional parameters including: the modified Rayleigh number (100 ≤ Ra* ≤ 1000), the Darcy number (10-6 ≤ Da ≤ 10-2), the Lewis number (0.1 ≤ Le ≤ 20), the buoyancy ratio (-5 ≤ N ≤ 5), the thermal conductivity ratio (0.1 ≤ Kr ≤ 10), the ratio of wall thickness to its height (0.1 ≤ D ≤ 0.4), the Soret parameter (-5 ≤ Sr ≤ 5), and the Dufour parameter (-2 ≤ Df ≤ 2).

We consider the inverse source problem arising in thermo-and photoacoustic tomography. It consists in reconstructing the initial pressure from the boundary measurements of the acoustic wave. Our goal is to extend versatile time reversal techniques to the case when the boundary of the domain is perfectly reflecting, effectively turning the domain into a reverberant cavity. Standard time reversal works only if the solution of the direct problem decays in time, which does not happen in the setup we consider. We thus propose a novel time reversal technique with a nonstandard boundary condition. The error induced by this time reversal technique satisfies the wave equation with a dissipative boundary condition and, therefore, decays in time. For larger measurement times, this method yields a close approximation; for smaller times, the first approximation can be iteratively refined, resulting in a convergent Neumann series for the approximation.

Orientador: Thiago Pedro Mayer Alegre / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Física Gleb Wataghin / Made available in DSpace on 2018-08-31T00:04:36Z (GMT). No. of bitstreams: 1 Benevides_RodrigodaSilva_M.pdf: 12114965 bytes, checksum: 9db892fbca5fe67d883b58515f6e1dc7 (MD5) Previous issue date: 2016 / Resumo: A área de optomecânica de cavidades passou por um grande desenvolvimento na última década. O crescente interesse nesta área foi impulsionado principalmente pela interessante conexão entre movimentos mecânicos e campos ópticos. Tal acoplamento é amplamente explorado em diversos experimentos, com escalas variando de interferômetros quilométricos a cavidades ópticas microestruturadas. O principal desafio em todos estes experimentos é criar um dispositivo optomecânico com um longo tempo de vida óptico e mecânico, ao mesmo tempo em que mantém um grande acoplamento. Neste contexto, as cavidades de cristal fotônico surgiram como fortes candidatas já que elas são capazes de confinar campo óptico em um volume modal muito reduzido e por um longo tempo de vida. No regime clássico, estes pequenos dispositivos, que podem oscilar mecanicamente com frequências de alguns poucos MHz até dezenas de GHz, permitem detectar forças, massas e deslocamentos muito pequenos. Elas também são usadas para produzir osciladores mecânicos de alta qualidade, que podem ser sincronizados por intermédio do campo óptico. No regime quântico, a optomecânica quântica de cavidades tem sido usada para ajudar na compreensão do fenômeno de decoerência em uma escala mesoscópica, criando estados não-clássicos fortemente acoplados entre campo óptico e movimento mecânico, intermediado pela interação optomecânica. Entretanto, até agora, foram realizados poucos estudos sobre a possibilidade de produção destes dispositivos em larga escala, um passo necessário para massivas aplicações tecnológicas e científicas destes dispositivos. Neste trabalho, descrevemos um estudo detalhado de cavidades optomecânicas baseadas em cristais fotônicos produzidos numa fábrica de dispositivos compatíveis com indústria CMOS. Nós demonstramos a viabilidade desta plataforma explorando três geometrias distintas de cristais fotônicos. Primeiramente, nós mostramos como atingir fatores de qualidade muito elevados usando uma geometria consistente com as limitações de fabricação. Nossos fatores de qualidade são os maiores já reportados usando cavidades de cristal fotônico fabricadas com litografia óptica. Em seguida, investigamos uma cavidade do tipo fenda, possibilitando a produção de alto acoplamento optomecânico usando um movimento mecânico planar. Por fim, desenhamos um escudo acústico, com dimensões variadas, para restringir o modo mecânico para dentro da região óptica. Essa estratégia foi usada de forma bem sucedida para produzir altos fatores de qualidade mecânicos e acoplamentos optomecânicos, permitindo a observação de resfriamento e amplificação de modos mecânicos à baixa temperatura / Abstract: The field of cavity optomechanics has experienced a rapid growth in last decade. The increasing interest in this area was mostly driven by the intricate interface between mechanical motion and the optical field. Such coupling is widely explored in a variety of experiments scaling from kilometer long interferometers to micrometer optical cavities. The challenge on all these experiments is to create an optomechanical device with long-living optical and mechanical resonances while keeping a large coupling rate. In this context photonic crystal cavities have emerged as a strong candidate since they are able to produce very small optical mode volume and long optical lifetime. In the classical regime, these tiny devices, which can mechanically oscillate from frequencies ranging from couple MHz up to tens of GHz, allows for highly sensitive small forces, masses, displacements and acceleration detectors. They are also used to produce high quality optically driven mechanical oscillators which can be synchronized via an optical field. In the quantum regime, cavity quantum optomechanics is being used to understand decoherence phenomena in a mesoscopic scale by creating nonclassical states between light and mechanical modes intermediated by optomechanical interaction. However up to now, few studies have been done concerning the possibility of large scale production of these devices, a necessary step towards massive technological and scientific application of these devices. In this work, we describe a detailed study of optomechanical cavities based upon photonic crystal cavities fabricated in a CMOS-compatible commercial foundry. We prove the feasibility of this platform exploring three photonic crystal designs. First, we show how to achieve ultra-high optical quality factors using a design resilient to the fabrication constrains. Our demonstrated quality factors are the largest ever reported using photonic crystal cavities manufactured by optical lithography. Secondly, we investigate a slot type optical cavity, able to produce very large optomechanical coupling using a simple in-plane motion. Finally, we design a trimmable acoustic shield to restrict the mechanical motion inside the optical region. Such strategy was successfully used to produce high mechanical quality factor and optomechanical coupling which enabled the observation of cooling and amplification of mechanical modes at low temperature / Mestrado / Física / Mestre em Física / 2014/12875-4 / 132737/2014-0 / FAPESP / CNPQ