Background: Many well-known pharmacologic agents have been shown to have toxic effects to the cochleo-vestibular system. Examples of such ototoxic agents include cisplatin and aminoglycoside antibiotics. Ototoxicity monitoring consists of a comprehensive pattern of audiological assessments designed to detect the onset of any hearing loss. Three main methods have emerged over the past decade, and include the basic audiological assessment, extended high frequency (EHF) audiometry, and otoacoustic emission (OAE) measurement. These measures can be used separately or in combination, depending on clinical purpose and patient considerations. It is suggested by the American Academy of Audiology Position Statement and Clinical Practice Guidelines: Ototoxicity Monitoring, that baseline testing be done in a fairly comprehensive manner, including pure-tone thresholds in both the conventional- and extended high frequency ranges, tympanometry, speech audiometry, and the testing of OAEs (AAA, 2009). Anecdotal evidence suggests that New Zealand Audiologists do not currently follow a national ototoxicity monitoring protocol. Therefore the main aim of this study was to explore the current status of ototoxicity monitoring within New Zealand. Hypothesis: It was hypothesized that hospital based Audiology departments across New Zealand each followed their own internal ototoxicity monitoring protocol based, to a large extent, on the guidelines proposed by the American Academy of Audiology and by the American Speech-Language-Hearing Association. Method: Through the use of a Telephone Interview Questionnaire, 16 charge Audiologists were interviewed to establish their current state of knowledge regarding ototoxicity monitoring at 16 out of 20 district health boards in New Zealand. Enquiries about the current systems and procedures in place at their departments together with any suggestions and recommendations to improve on these systems were made. Results: This study found that only 9 of the 16 DHBs interviewed currently follow an ototoxicity monitoring protocol. Furthermore, other than initially hypothesized the origin of the protocols followed by the remaining 7 departments were reported to have ranged from independently developed protocols to historically adopted protocols. One department implemented an adapted version of a protocol by Fausti et al. (Ear and Hearing 1999; 20(6):497-505). This diversity in origin however, does confirm our initial suspicion that no universal and standardized monitoring protocol is currently being followed by Audiologists working in the public health sector of New Zealand.

The aim of this work was the analysis of the current state od cadastral area Krásná. Available materials were collected, analyzed and evaluated. Procurations were proposed on the basis of these activities to improve conditions in the areas of soil conservation, water management conditions, the landscape environment and, last but not least, the transport system and access to land. Form and content were chosen so that the work could be used as a basis for a plan of common facilities.

This thesis is devoted to research the current state of insurance in Russia. The target of the analyse are the factors affecting its appearance and to characterize development tendencies of the modern market.

I Sverige är 99.9 % av alla företag SME-företag. I dagens samhälle har förändrade förutsättningar och globala marknader ändrat kundkraven på exempelvis ledtid. Svenska tillverkande SME-företag kräver således ett sätt att anpassa sin produktion till dessa förändrade förutsättningar. VSM är en metod där current- och future-state mappas för att tydliggöra hur produktionen ser ut idag och hur det ska se ut imorgon. Det påvisas dock i tidigare studier att det finns hinder med VSM som motverkar framtagning av FSM. Det ska dock noteras att merparten av de studier som tidigare utförts har gjorts vid utländska företag eller företag större än SME. Dessa studier har dessutom genomförts i syfte att observera VSM i helhet och de fördelar som metoden har, eller undersöka vissa få hinder. Syftet med arbetet är därför att undersöka vilka hinder som kan försvåra för svenska SME-företag att designa future-state värdeflödeskartor som är lämpliga sett till deras verksamhet. Detta för att bättre möjliggöra för VSM implementation hos dessa företag. Detta har utförts genom att jämföra tidigare litteratur med en fallstudie på ett svenskttillverkande SME-företag inom metallindustrin och undersöka de mönster i hindren som observerats. Resultatet av arbetet var en modell av hinder som kan komma att försvåra försvenska SME-företag att designa future-state värdeflödeskartor som är lämpliga sett till deras verksamhet. Från denna modell tydliggörs ett stor överlapp mellan det empiriska resultatet och resultatet från tidigare studier. Ett hinder från tidigare litteratur motbevisas även och exkluderas från modellen. Detta medför att framtida utövare på svenska tillverkande SME-företag aktivt kan göra sig medvetna om de hinder som de kan tänkas stöta på samt vad dessa kan ha för påverkan på deras FSM, och genom detta förbereda sig för att möta dessa hinder. Framtida studier skulle kunna undersöka hinder vid användning av VSM-metoden på flera olika svenska tillverkande SME-företag och således skapa en bredare bild av hinder med VSM för framställning av en FSM / In Sweden, 99.9% of all companies are SMEs. In today's society, changing conditions and global markets have altered customer requirements, such as lead time. Therefore, Swedish manufacturing SMEs require a way to adapt their production to these changing conditions. Value Stream Mapping (VSM) is one such method that maps the current and future states to clarify how production looks today and how it should look tomorrow. However, previous studies have shown that there are obstacles with VSM that hinder the development of Future State Maps (FSMs). It should be noted that the majority of previous studies have been conducted in foreign or larger-than-SME companies. These studies have also been carried out to observe the entirety of VSM and its benefits or to investigate a few specific obstacles. The purpose of this study is to examine the obstacles that may hinder Swedish SMEs from designing future-state value stream maps suitable for their operations, in order to better enable VSM implementation in these companies. This has been accomplished by comparing previous literature with a case study conducted at a Swedish manufacturing SME in the metal industry and examining the patterns observed in the obstacles. The result of this work was a model of obstacles that may hinder Swedish SMEs from designing future-state value stream maps suitable for their operations. This table clearly shows a significant overlap between the empirical findings and the results from previous studies. Additionally, one obstacle from previous literature is contradicted. As a result, future practitioners in Swedish manufacturing SMEs can actively become aware ofthe obstacles they may encounter and understand their impact on their FSMs, thereby preparing to address these obstacles. Future studies could investigate obstacles in the use of the VSM method in several different Swedish manufacturing SMEs to create a broader understanding of obstacles with VSM for the development of an FSM.

Submitted by Renata Lopes (renatasil82@gmail.com) on 2018-05-17T15:41:45Z No. of bitstreams: 0 / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2018-05-22T11:40:07Z (GMT) No. of bitstreams: 0 / Made available in DSpace on 2018-05-22T11:40:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-02-26 / O desengajamento moral (DM) é um processo psicossocial que desativa o padrão moral interno de condutas desumanas, silenciando a autocondenação. Assim, três estudos foram conduzidos para analisar o DM por diferentes prismas. Especificamente, os objetivos foram: analisar o estado atual da arte das pesquisas sobre DM (Estudo 1); obter uma versão traduzida e adaptada para o Brasil da principal medida de DM, a Multifaceted Scale of Mechanisms of Moral Disengagement - MSMMD, buscando evidências de validade e estimativas de fidedignidade (Estudo 2); e investigar as relações entre DM e variáveis demográficas e educacionais (Estudo 3). O Estudo 1 revelou que este fenômeno tem sido relacionado a um número bastante grande de comportamentos transgressivos que variam em termos de gravidade, que o DM se manifesta em diversos contextos e em diferentes fases do curso de vida, que predominam estudos correlacionais e que são escassos os estudos sobre DM no Brasil, bem como que há carência de medidas com evidências de validade e fidedignidade para esse contexto. O Estudo 2 denotou que a versão brasileira da MSMMD parece ser multidimensional, sendo o modelo teórico – quatro conjuntos de mecanismos que agrupam oito mecanismos e dão origem a um total – a estrutura interna mais adequada para a medida. A escala apresenta boa consistência interna para o total de itens, porém, a maioria dos fatores e componentes apresentou Alfas de Cronbach inferiores ao esperado. Também foram encontradas evidências de validade para a MSMMD baseadas na relação com outras variáveis, mais precisamente empatia, comportamentos prossociais e atos infracionais. Embora não esteja isenta de limitações, a versão brasileira da MSMMD pode ser considerada um recurso útil para pesquisas brasileiras sobre DM. Ademais, recomenda-se que mais estudos sobre suas propriedades psicométricas sejam realizados. O Estudo 3 identificou que meninos, alunos com menor idade e com menor número de anos estudados, estudantes de instituições de ensino públicas e com histórico de reprovação escolar apresentaram maior DM. Religião não se associou ao DM de forma geral, porém os mecanismos Justificação Moral e Linguagem Eufemística foram menos utilizados pelos participantes que possuem e são praticantes de religião. Neste estudo, Justificação Moral foi o mecanismo mais utilizado pelos estudantes e Comparação Vantajosa o menos utilizado. Não obstante as limitações, as três pesquisas que compõem a presente dissertação abrem, ainda que modestamente, caminhos para futuras pesquisas sobre DM no contexto brasileiro. / Moral disengagement (DM) is a psychosocial process that deactivates the internal moral standard of inhuman conduct, silencing self-condemnation. Thus, three studies were conducted to analyze DM by perspectives different. Specifically, the objectives were: to analyze the current state of the art of researches on DM (Study 1); to obtain a translated and adapted version for Brazil of the main measure of DM, the Multifaceted Scale of Mechanisms of Moral Disengagement - MSMMD, seeking evidence of validity and reliability estimates (Study 2); and to investigate the relationships between DM and demographic and educational variables (Study 3). Study 1 revealed that this phenomenon has been related to a fairly large number of transgressive behaviors that vary in severity, that DM manifests itself in several contexts and in different phases of the life course, that predominate correlational studies and that are scarce the studies on DM in Brazil, as well as that there is a lack of measures with evidence of validity and reliability for this context. Study 2 denoted that the Brazilian version of MSMMD appears to be multidimensional, with the theoretical model - four sets of mechanisms that group eight mechanisms and give rise to a total - the most adequate internal structure for the measure. The scale presents good internal consistency for the total of items, however, most of the factors and components presented Cronbach's Alphas lower than expected. Evidence of validity for MSMMD was also found based on the relationship with other variables, more precisely empathy, prossocial behavior and infractional acts. Although not exempt from limitations, the Brazilian version of MSMMD can be considered a useful resource for Brazilian research on DM. In addition, it is recommended that further studies on MSMMD psychometric properties be performed. Study 3 identified that boys, students with lower age and with less number of years studied, students of public institutions with a history of school failure showed higher DM. Religion was not associated with DM in general, but the Moral Justification and Euphemistic Language mechanisms were less used by participants who have and are practicing religion. Moral Justification was the mechanism most used by students and Advantageous Comparison less used. Despite the limitations, the three researches that compose this dissertation open, albeit modestly, ways for future researches on DM in the Brazilian context.

The subject of the diploma thesis is the geodetic survey of historical part of Dominican monastery in Znojmo city and to create documentation of the building. The thesis contains a description of the place of interest, preparation for work and measuring process. Next part the thesis deals with the requirements of creating the drawing documentation of the ground plan and the vertical section and also testing results of the work. The final documentation will be used for the reconstruction of the building.

This master´s thesis deals his issue of company performance measurement. In the first part there is given theoretical framework of this topic. The practical part contains analysis of the current situation of the company with two competitors. Based on the analysis there are proposing measures, which will contribute to improving business performance.

This thesis is focused on study of process during the engagement in small company Podlahy Lakomý, which deals with realization of floor work. Thesis is divided to three main parts. First part is concerned with the theoretical knowledge. Second part focusing on the analysis of the current status process of order. In the last part are mentioned proposals for amendments, which leading to streamline entire order process.

This project aims to present machine tool characteristics which may induce limiting factors in terms of flexibility. The aim is also to present a current state description of the machine tools in the production system regarding their characteristics in terms of quantifiable results. This refers to visual presentation in the form of graphs of the distribution of these characteristics among the different machine tools. A literature study was conducted to attain knowledge of machine tools and how the literature defines machine tool flexibility. Based on this, the flexibility parameters were identified. The result illustrates the current state description of the machine tools found in Volvo truck’s factory in Köping. These machine tools are lathe machines, machine centers, gear cutting machines and grinding machines. The result presents a percentage breakdown for each parameter for each of the machine types regarding the number of machines which possess a specific characteristic. The result displayed various cases of data missing. In many cases only a small percentage of data was missing, thus this result should be a sufficient representation of the situation. Meanwhile in other cases more data was missing and it leads to the result being less accurate. Overall, the acquired data in most cases should be sufficient to provide a current state description of the machines in the factory. There is no clear definition of flexibility referenced by the literature, hence it is difficult to conduct a quantitative evaluation. Moreover, there are many parameters presented in this work which emphasizes the multidimensional complexity of the problem. The parameters presented in this project directly influence the type of operations required, geometrical complexity of the workpiece, number of setups and size of workpiece which the machine is capable of handling. The machines have been grouped into the four categories mentioned above. This was done to reduce the complexity of the problem, hence not investigating each sub-category of machine (for example hobbing, skiving, etc.) The work has chosen not to group the machines based on the article they process as this would require additional knowledge of the layout and flow of material in the factory. The chosen approach will provide more of a generic visualization. A method has been developed to present a current state description of a manufacturing system regarding machine tool flexibility and how they can be evaluated. This process includes data collection and documentation of machines tools for the flexibility parameters. Hence, it can be presented how the machines within each machine type possess a specific attribute in terms of numbers or fit within a certain interval. The purpose is to present visual results of the data to illustrate for the reader the distribution of the machine characteristics for each of the machine types and parameters. / Detta projekt har som mål att presentera egenskaper hos bearbetningsmaskiner som kan medföra begränsande faktorer kopplat till flexibilitet. Målet är också att presentera en nulägesbeskrivning av bearbetningsmaskinernas egenskaper i produktionssystemet i form av kvantifierbara resultat. Detta refererar till visuella presentationer i form av grafer angående distribueringen av dessa egenskaper bland de olika bearbetningsmaskinerna. En litteraturstudie har genomförts för att tillhandahålla kunskaper om bearbetningsmaskiner och hur litteraturen definierar flexibilitet hos bearbetningsmaskiner. Resultatet illustrerar nulägesbeskrivningen av bearbetningsmaskinerna som befinner sig i Volvo Trucks fabrik i Köping. Dessa bearbetningsmaskiner är svarvar, fleroperationsmaskiner, kuggbearbetningsmaskiner och slipmaskiner. Resultatet visar en procentuell uppdelning av varje parameter for varje maskintyp, angående antalet maskiner som besitter en viss typ av egenskap. Resultatet visade på olika fall av saknad av data. I många fall saknades endast en liten andel av data, därmed bör detta resultat ge en tillräcklig representation av situationen. I andra fall saknades mer data och det leder till att resultatet blir mindre exakt. Överlag bör den insamlade datan i de flesta fall vara tillräcklig för att presentera en nulägesbeskrivning av maskinerna i fabriken. Det finns ingen tydlig definition av flexibilitet som nämns i litteraturen, därmed medför detta svårigheter att utföra en kvantitativ utvärdering. Dessutom presenteras det många olika parametrar i detta arbete, vilket understryker problemets flerdimensionella komplexitet. Parametrarna presenterade i detta arbete påverkar direkt vilken typ av operation som behövs, geometriska komplexiteten av arbetsstycket, antalet uppspänningar och storleken på arbetsstycket som maskinen kan hantera. Maskinerna har grupperats i fyra olika kategorier som nämndes ovan. Detta gjordes för att minska komplexiteten av problemet, därmed undersöks inte underkategorierna av maskinerna (till exempel hobbing skiving etcetera). Arbetet har valt att inte gruppera maskinerna baserat på vilken artikel de bearbetar, eftersom detta skulle behöva ytterligare kunskaper om layouten och flödet av material i fabriken. Det valda tillvägagångssättet ger en mer generell visualisering. En metod har tagits fram för att presentera en nulägesbeskrivning av ett produktionssystem med avseende på flexibiliteten hos bearbetningsmaskiner och hur de kan utvärderas. Denna process inkluderar datainsamling och dokumentation av flexibilitetsparametrarna hos bearbetningsmaskinerna. Därmed kan det presenteras hur maskinerna inom varje maskintyp besitter en specifik egenskap i form av siffror eller passar inom ett specifikt intervall. Syftet är att presentera visuella resultat av datan för att illustrera för läsaren om distribueringen av maskinegenskaperna för varje maskintyp och parameter.

Through a thorough analysis of the current situation, we have highlighted differences in working methods for the various workshops and drew up proposals for improvements in combination with a practical work description that can be implemented in the company.