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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Retrospective analysis of bevacizumab and cetuximab in advanced Asian colorectal cancer patients

Zhang, Qian, 张茜 January 2015 (has links)
Colorectal cancer is a serious health problem that has concerned people for decades. In Hong Kong, it is the most common cancer and the second leading cause of death. Among colorectal cancer patients, around 40-50% of them will develop metastatic disease. Chemotherapy is playing an important role all the time in the treatment of advanced colorectal cancer. In the past decade, the application of targeted therapies in treatment has largely improved efficacy and prolonged survival. Bevacizumab and cetuximab are two commonly used targeted agents in daily clinical practice of Hong Kong. Since multiple clinical trials have studied bevacizumab and cetuximab in combination with other chemotherapies, limited data is available in Asian patients. Therefore, we conduct three 5-year retrospective analyses based on patients received treatment in Hong Kong Queen Mary Hospital, to investigate the clinical efficacy and toxicity of those two drugs. The first study examined the use of bevacizumab in treating KRAS mutated type patients. We found the efficacy and results were consistent with historical data. In the next analysis of cetuximab, comparable data were shown which suggested the consistency with previous studies. The last study is aim to compare bevacizumab and cetuximab in previously untreated wild-type KRAS patients. Identical response rates, progression-free survival and overall survival were finally reported. / published_or_final_version / Medicine / Master / Master of Philosophy
2

Characterization of phospholipid transfer protein (PLTP) in hepatocellular carcinoma

盧家健, Lo, Ka-kin. January 2007 (has links)
published_or_final_version / abstract / Surgery / Master / Master of Philosophy
3

The expression of major histocompatibility complex antigens by renal cell carcinomas

Angus, Rachel January 1993 (has links)
No description available.
4

The development of synthetic low density lipoproteins for drug delivery

Bone, Gavin January 2001 (has links)
No description available.
5

The hepatobiliary transport of purine and pyrimidine chemotherapeutic drugs

Hobby, Kirsten Raoul January 1996 (has links)
No description available.
6

Novel natural products as modifiers of multidrug resistance

Holmes, Julie Ann January 1995 (has links)
No description available.
7

Aromatic nitrogen mustards

Pamplona, Maria Teresa Troina January 1994 (has links)
No description available.
8

Fluorescence based assay for the identification of multidrug resistance in transitional cell bladder carcinoma

Hayes, Matthew Charles January 2000 (has links)
No description available.
9

The interaction of mithramycin with DNA

Cons, Benjamin Major George January 1990 (has links)
No description available.
10

An organometallic approach to total synthesis of phyllanthocin

King, Andrew John January 1995 (has links)
No description available.

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