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Secreted aspartyl proteinases of Candida albicans with particular relevance to the oral cavity吳韜, Wu, Tao. January 1997 (has links)
published_or_final_version / Dentistry / Doctoral / Doctor of Philosophy
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Biodiversity of springtails (Insecta : Collembola) in urban soilsFountain, Michelle T. January 2002 (has links)
No description available.
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Chitinolytic enzymes of Candida albicansO'Donnell, Raymond William January 1991 (has links)
It has been envisaged that lytic enzymes may be crucial in determining the morphology and growth of fungi, and may therefore represent a target for antifungal agents. The chitinolytic system of <i>Candida albicans</i> was investigated using a range of 4-methylumbelliferyl glycosides as model substrates, and its potential as a target for antibiotics has been assessed. Maximum hydrolysis was obtained with substrates having monomer and tetramer chain lengths, being attributed to <i>N</i>-acetylglucosaminidase and endochitinase respectively. Activities were investigated in cell fractions, vacuoles, and also in whole cell preparations. The characteristics of both chitinase and <i>N</i>-acetylglucosaminidase were examined, including pH and temperature optima and Km values. Chitinase was semi-purified on Fast Protein Liquid chromatography system and activity could be located after native polyacrylamide gel electrophoresis. Analysis of chitinase activity during the growth of the yeast morphology of <i>C.albicans</i> revealed maximal activities during the logarithmic phase, suggesting a relationship of chitinase levels to active growth of the pathogen. It was found that the antibiotic allosamidin was a potent inhibitor of chitinase activity of <i>C.albicans</i>, but not of <i>N</i>-acetylglucosaminidase. Conversely, an analogue of <i>N</i>-acetylglucosamine was found to be a potent inhibitor of <i>N</i>-acetylglucosaminidase but not of chitinase. Treatment of yeast suspensions with allosamidin resulted in an increased chain length. No cell death, or discernible pattern of change in the radiolabelling was observed in the presence of either allosamidin or <i>N</i>-acetylglucosamine analogue. Similarly no consistent change in the optical density of cultures was observed in the presence of either inhibitor. Even in the presence of the membrane permeabilising agent amphotericin no effects were observed above those achieved with amphotericin alone. Comparative studies were carried out upon the chitinolytic activity of <i>Kluyveromyces lactis</i> toxin and bovine serum. The chitin synthetic system of <i>Benjaminiella poitrasii</i> was compared to that of <i>C.albicans</i>.
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Effect of protease inhibitors on adherence of Candida albicans to acrylic surfaceHong, Wai-man, Ivis. January 2008 (has links)
Thesis (M. D. S.)--University of Hong Kong, 2008. / Includes bibliographical references (leaf 51-57) Also available in print.
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Pho2 dependence in the phosphate signal transduction pathway of Saccharomyces cerevisiae and Candida glabrataKerwin, Christine. January 2008 (has links)
Thesis (M.S.)--Villanova University, 2008. / Biology Dept. Includes bibliographical references.
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The impact of the oral environment on Candida biofilm developmentThein, Zaw Moe. January 2007 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2007. / Title proper from title frame. Also available in printed format.
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Production par fermentation et structures chimiques d'une famille de biosurfactants : les sophorolipides de Candida bombicola... /Davila, Anne-Marie. January 1900 (has links)
Th. doct.--Biol. cellulaire et microbiol.--Aix-Marseille 1, 1993. / 1993 d'après la déclaration de dépôt légal. Bibliogr. p. 143-151.
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Secreted aspartyl proteinases of Candida albicans with particular relevance to the oral cavity /Wu, Tao. January 1997 (has links)
Thesis (Ph. D.)--University of Hong Kong, 1997. / Includes bibliographical reference (leaves 212-241).
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The post-antifungal effect (PAFE) and its impact on the pathogenic attributes of Candida albicans /Ellepola, Arjuna Nishantha Bandara. January 1999 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2000. / Includes bibliographical references (leaves xxvi-xxvii, 261-311).
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In vitro interactions of Candida species and oral bacteria /Nair, Gopinathan Raj. January 1996 (has links)
Thesis (Ph. D.)--University of Hong Kong, 1997. / Includes bibliographical references (leaves 246-271).
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