Estágio realizado na Qimonda Portugal, S.A. e orientado pelo Doutor Rui Batista / Tese de mestrado integrado. Engenharia Metalúrgica e de Materiais. Faculdade de Engenharia. Universidade do Porto. 2008

Cisplatin (cis-diamminedichloroplatinum(II)) and its analogs are known to form 1,2-intrastrand cross-links with guanine bases that lead to DNA distortion and are responsible for cytotoxicity. Reaction with proteins, especially at methionine residues, could also be responsible for cytotoxicity (Sandlin, R. D. et al. 2010). A new tridentate platinum(II) complex with a piperazine ring was successfully designed and synthesized. In this complex, the platinum is coordinating to all three nitrogens of (1,2- dimethylaminoethylpiperazine), which makes it a Platinum triamine compound. A series of chemical reactions of this compound with guanosine 5’-monophosphate (5’-GMP) and N-acetylmethionine (N-AcMet) were conducted under different conditions. Reactions with 5’-GMP show spectra suggesting that the triamine ligand is partially displaced as a second 5’-GMP residue coordinates. We are hoping that this newly synthesized compound may have anticancer properties, due the bulky structure of its nitrogen ligand.

"September, 2004" / Bibliography: p. 119-136. / ix, 136 p., [25] p. of plates : col. ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / The transcription factor gene, dead ringer (dri), is expressed in a dynamic pattern in both the Drosophila embryo and eye. This thesis has identified pleiotropic roles for dri in eye development and in adult eye function. / Thesis (Ph.D.)--University of Adelaide, School of Molecular and Biomedical Sciences, Discipline of Genetics, 2005

Thesis (M. Phil.)--University of Hong Kong, 2007. / Title proper from title frame. Also available in printed format.

No description available.

The orientation relationship and interfaces of Au5Sn with the Au (001), (110) and (111) surfaces have been studied with transmission electron microscopy. Au was evaporated onto the NaCl (001), (110) and (111) surfaces to form epitaxial Au thin films and Sn was evaporated onto the Au film and heat treated to form Au5Sn. Two types of orientation relationships were found: (1) (2-1-10)Au5Sn/(001)Au¡A(0006)Au5Sn //(-220)Au and (03-30)Au5Sn//(220)Au, which was found on the (2-1-10)Au5Sn/(001)Au interface; and (2) (2-1-10)Au5Sn/(-111)Au¡A(0006)Au5Sn //(-22-4)Au and (03-30)Au5Sn//(220)Au, which was found on the (2-1-10)Au5Sn/(-111)Au interface.The structures of the interfaces were analyzed. The free energy formation of AuSn is much larger than that of Au5Sn.Analysis of above results show that the differences of the interfacial energies between AuSn/Au and Au5Sn/Au may not be a significant. Therefore probably has a lower activation energy of AuSn nucleation and in the first plane to form at the AuSn interface.

The study and application of machine vision in early years mostly focus on a single camera. However, the trend of research on multiple cameras has been developed recently. Due to highly complicated correlation among multiple images, the arrangement of multiple cameras was restricted to the encirclement layout for acquiring more than one views of a target object. Furthermore, it has been well known that the special architecture of insect compound eyes contributes outstanding capability for precise and efficient observation of moving objects. If this technique can be transferred to the domain of engineering applications, significant improvement on visual tracking of moving objects will be greatly expected. This thesis builds a visual servo system with trinocular cameras by mimicking the configuration of compound eye of insects for tracking an object moving in 2D space. The arrangement of the trinocular cameras is divergent, and this system can function properly without the information of distance between the object and the cameras.

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The present study aims to explore flow behavior in the mold during centrifugal casting process by numerical simulations. The theoretical model comprises two groups of steady conservation equations of mass and momentum and the governing equations are solved numerically with k-£` turbulence model and iterative SIMPLE(Semi-Implicit for Pressure-Linked Equations) algorithm to determine the flow property. The numerical results indicate that the melt liquids of titanium compound metal flow near the walls in the high rotation rate. With the high rotation rate, the outflow velocity is rapid. The products depend on the flow of the melt liquids. The flow is rapid, the filled process is quick, and the temperature is uniform. But if the flow is slow, the temperature is not uniform in the filled process. Therefore, the products may result in faults. When the rotation rate is up to 50 rpm, the melt liquids flow near the walls with the affect of centrifugal force. The velocity is larger than the velocity with zero rotation rate . Thus the flow with rotation rate can help to fill quickly, and reduce the temperature loss.

The purpose of thesis is to study the transient analysis of structural responses of solder joints under high-Speed impact. By using the experimental and simulation analysis. The experimental work can be divided into six parts, such as different impact speeds, different solder¡¦s components, different pad finishing, different UBM and Runner, and different thickness of PBO. From experiments, the variations of solder joint strength and mechanical properties were received and discussed and the failure mode. The empirical results show that maximum impact force on solder joints decreases as the impact speed increasing. The solder joint strength becomes stronger with the solder adopting elements of Ni and Co. The strength of solder ball was reduced significantly after a reflow. The intermetallic compound strength reduces with solder ball adopting high content of Ag. In impact test, the resistance of UBM of TiAl is better than that of TiAlTi. The runner adopted with the element Pd can improve the IMC reliablility to reduce Mode I failure. However, the PBO thickness has little influence on IMC strength. From the numerical results, in the consideration of strain rate on solder joint the mechanical properties of solder joint could be effectively investigated. According to the different IMC strength there will produce three failure modes of solder ball and the impact force becomes higher as the IMC strength setting higher. If the lower yield stress is considered in lower IMC strength, the impact force is not the highest of all, but the time duration is the highest of all.