Cas à part dans le cinéma britannique contemporain, depuis 30 ans la société de production Working Title Films connaît un succès régulier sur la scène internationale. Son box-office cumulé se compte en milliards de dollars pour une centaine de longs métrages, qui lui ont valu des dizaines d'Oscars et de BAFTA, ainsi que quelques distinctions à Cannes, Berlin ou Venise. Ce succès attire pourtant les critiques de certains commentateurs, qui lui reprochent de se laisser submerger par les conventions du cinéma hollywoodien et de manquer d'ambitions culturelles, notamment à cause de son contrat avec la major Universal et de ses stratégies de distribution. Ils déplorent les représentations stéréotypées de la « britannicité » de certains de ses films, à l'instar des comédies de Richard Curtis ou de Rowan Atkinson. En effet, si Working Title a débuté avec un film audacieux, My Beautiful Laundrette (Stephen Frears, 1985), son premier grand succès commercial est Four Weddings and a Funeral (Mike Newell, 1994). Néanmoins, malgré leurs ambitions commerciales mondiales, Tim Bevan et Eric Fellner, les directeurs de Working Title, revendiquent leur britannicité et une « sensibilité européenne ». Celle-ci est concrétisée par un partenariat avec PolyGram Filmed Entertainment puis avec StudioCanal. Cette dimension transnationale – plutôt que transatlantique – n'est pas sans influence sur les films eux-mêmes, et concourt également à leur succès international. Plusieurs intrigues mettent même en scène des relations interculturelles. Les films affichent des stratégies de compromis entre spécificité culturelle et universalité, avec des équilibres changeants. En effet, on ne peut nier la diversité déconcertante de la filmographie, tant du point de vue des contenus culturels que du degré de créativité. Working Title collabore avec des réalisateurs britanniques d'horizons variés, comme Richard Curtis, Stephen Frears, Edgar Wright ou Joe Wright. De plus, elle franchit souvent les frontières nationales, essentiellement outre-Atlantique, en particulier grâce à son partenariat avec les frères Coen, mais aussi en Australie, en Afrique du Sud ou dans d'autres pays européens. Tout cela place donc Working Title au cœur des débats sur les enjeux du cinéma britannique actuel, concernant son identité (cinéma national / post-national), l'équilibre entre les aspects économiques et artistiques, les relations avec Hollywood, ou encore le rôle des politiques culturelles. Ainsi, cette thèse tâche de comprendre l'évolution et le succès de cette société phare du cinéma britannique, en s'attachant autant à l'étude de son fonctionnement (partenariats, développement, production, distribution) qu'à l'analyse textuelle de ses films. / A unique entity in today's British film industry, production company Working Title Films has been responsible for many international hits since its creation in 1984. Its films have earned billions of dollars, and they have won many film awards, including dozens of Academy Awards and BAFTA Awards, but also accolades in Cannes, Berlin or Venice. Yet, some commentators criticize Working Title for being excessively influenced by Hollywood, hence lacking cultural ambitions. They blame the company's partnership with Universal and underline that some of its films broadcast a stereotypical view of Britishness, especially successful comedies by Richard Curtis, or the ones starring Rowan Atkinson. Indeed, the company's first film was My Beautiful Laundrette (Stephen Frears, 1985), a creative, committed film, but its more recent films tend to be more mainstream and its first international hit was Four Weddings and A Funeral (Mike Newell, 1994). However, Working Title seems to draw some of its strength from its British identity. Tim Bevan and Eric Fellner, the two producers behind Working Title, also defend its “European sensibility”. The latter is reinforced by a partnership with PolyGram Filmed Entertainment in the nineties, and then with StudioCanal. So it is a transnational rather than a transatlantic company. Its films are transnational too, and some plots even include intercultural relationships. They use various strategies to broaden their audience, such as crossover and polysemy, and they try to balance cultural specificity with universality. However, most importantly, one cannot deny the incredible diversity of the films – regarding both their national identity and their level of creativity. Therefore, Working Title offers a fascinating case study to learn more about the issues of British cinema, about its identity (national / post-national cinema), the balance between art and industry, its relationship with Hollywood, and the role of cultural policies. In other words, this dissertation will study the evolution of Working Title Films, focusing on its methods, its strategies and also on the textual analysis of its diverse films, as a way to investigate contemporary British cinema and its issues.

Orientador: Ricardo de Lima Zollner / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas / Made available in DSpace on 2018-08-23T16:26:14Z (GMT). No. of bitstreams: 1 Colomeu_TalitaCristina_M.pdf: 1606110 bytes, checksum: ed843e2069440cf659e4ab7cc6c4c21f (MD5) Previous issue date: 2013 / Resumo: A linhagem NOD (non obese diabetic) é utilizada como modelo experimental de DM-1, pois desenvolve espontaneamente a doença com marcante similaridade ao observado em humanos. Vários são os mecanismos propostos para ruptura da tolerância imunológica no DM-1, como a predisposição genética do indivíduo, juntamente com fatores ambientais, tais como estresse e alimentação, parecem favorecer o desencadeamento de mecanismos auto imunes. Nos últimos anos o interesse por alimentos fitoterápicos pelos órgãos governamentais, com a finalidade de auxiliar no tratamento de doenças vem aumentando. A espécie Passiflora sp., é descrita pela farmacopeia Brasileira como fitoterápico e seu uso na medicina popular está relacionado ao tratamento de diversas doenças. Estudos sobre as propriedades das folhas do Passiflora alata Curtis no diabetes mellitus são escassos. Neste contexto, investigamos quais os melhores solventes (água, etanol e metanol/acetona) para extração de compostos bioativos da folha de P.alata, a atividade antioxidante dos solventes pelas técnicas DPPH, FRAP, ABTS e ORAC, fenóis totais, composição centesimal e investigação de quatro compostos fenólicos (vitexina, isovitexina e isoorientina) nas folhas. Além disso, avaliamos as propriedades do consumo crônico do extrato aquoso das folhas de P.alata sobre a incidência do DM-1, a insulite, os níveis de GSH no fígado/rim, a insulina sérica nos camundongos NOD e o estresse oxidativo, a apoptose e a imunofluorescência de infiltrados CD4+,CD8+ e CD11+ nas ilhotas pancreáticas desses animais. Nossos resultados sugerem que o extrato aquoso em comparação com o metanol/acetona e etanólico, apresenta atividade antioxidante e fenóis totais superiores e que seu consumo crônico é capaz de diminuir o índice de infiltrado inflamatório e consequentemente a expressão do diabetes, ajudar a manter os níveis de GSH no fígado/rim e reduzir o estresse oxidativo e apoptose nos camundongos NOD / Abstract: The strain of NOD mice (non obese diabetic) is common used for study with type 1 diabetes mellitus, because develops spontaneously the disease with strong similarity to the observed in humans. Several mechanisms are proposed to break immune tolerance in DM-1, such as genetic predisposition, environmental factors, as infections and dietetic, seem to favor the triggering of autoimmune mechanisms. In recent years the interest in herbal foods in order to prevent diseases is increasing in the population. The species Passiflora sp. is described by Brazilian Pharmacopoeia as herbal medicine and in folk medicine is related to the treatment of various diseases. Studies about properties of leaves of Passiflora alata Curtis related with diabetes mellitus are scarce. In this context, we investigate what the best solvent (water, ethanol and methanol/acetone) for the extraction of bioactive compounds from P.alata leaf, the antioxidant activity of the solvents by DPPH, FRAP, ABTS and ORAC, total phenols, composition and investigation of four phenolic compound (vetexin, isovitexin and isoorientin) in leaves. Furthemore, we evaluated the chronic consumption of aqueous extract on incidence of DM-1, insulits, GSH levels in liver/ kidney, serum insulin in NOD mice and oxidative stress, apoptosis and immunofluorescence of infiltrated CD4+,CD8+CD11+ in the pancreatic islets of these animals. Our results suggest that the aqueous extract shows higher values of antioxidant activity, total phenols and the chronic consumption can reduce the number of inflammatory infiltrate and consequently the expression of diabetes, help maintain the levels of GSH in the liver / kidney and reduce oxidative stress and apoptosis in NOD mice / Mestrado / Clinica Medica / Mestra em Clínica Médica

The goal of this Master’s thesis is to create the design of a low power condensing steam turbine. The turbine has a Curtis control stage and a reaction blading. The work also contains the calculation of gland labyrinth seals and the balancing piston, specification of a forces and losses at bearings. Finally, the gearbox and generator are selected and the efficiency at generator’s clamps is specified. The Master’s thesis includes the design drawing of a longitudinal turbine view.

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The purpose of this thesis was to create an Online Mentoring website that would benefit teachers by helping them to feel more confident and efficient through their first couple of years teaching. Its focus is to provide new teachers access to all information involving its processes, procedures and expectations within a specific school site.

This diploma thesis performs a calculation of a steam turbine to drive a feed pump. The research part deals with the basic classification of steam turbines focusing on mechanical drive steam turbines. The second part of the thesis is a controlled extraction pressure optimization for achieving the maximum possible thermic efficiency of the cycle. The last part of the thesis shows a detailed thermodynamic calculation of the mechanical drive turbine along with the basic geometric parameters of the flow canal.

In the late 1970s, a method was developed to estimate acoustic intensity in one dimension by taking the cross-spectral density of two closely-spaced microphone signals. Since then, multimicrophone probes have been developed to measure three-dimensional intensity as well as energy density. Their usefulness has led to the design of various types of multimicrophone probes, the most common being the four-microphone orthogonal, the four-microphone regular tetrahedron, and the six-microphone designs. These designs generally either consist of microphones suspended in space near each other or mounted on the surface of a sphere. This work analytically compares the relative merits of each probe design in measuring acoustic intensity and investigates the various finite-sum and finite-difference processing methods used with each. The analysis is limited to probes consisting of perfect point sensors in plane wave fields. The comparison is given in terms of average and maximum errors for intensity magnitude and direction as a function of angle of incidence as well as the spread between maximum and minimum errors for intensity magnitude. After existent probe geometries are reviewed, optimization techniques are introduced to predict what the optimal probe geometry would be for any given scenario. The probe is optimized to give the lowest intensity error averaged over angle of incidence of plane waves. This is done for full-space and half-space scenarios.

No description available.

Using flake dimensions and attributes commonly agreed are associated with site use, occupation age, and occupation duration, it was argued that relative estimations of site function and occupation age could be determined using debitage. This is particularly beneficial for assemblages that have little to no diagnostics that could provide a general cultural period for one or more occupations at a site. The results of this study suggest that, although certain attributes are generally associated with lithic production stage, relative age, and duration indicators, they were not all applicable within this study. The methods employed were relatively successful; however, reducing the number of classes, removing of a dimension, and more sites that meet the definition of lithic scatter is needed. Furthermore, testing occupation duration using the number of breaks on a flake is not possible unless it is proven a single occupation site.

3D seismic attribute analysis of the Jurassic Entrada/Curtis interval within the North Hill Creek (NHC) survey has been useful in delineating reservoir quality eolian-influenced dune complexes. Amplitude, average reflection strength and spectral decomposition appear to be most useful in locating reservoir quality dune complexes, outlining their geometry and possibly displaying lateral changes in thickness. Cross sectional views displaying toplap features likely indicate an unconformity between Entrada clinoforms below and Curtis planar beds above. This relationship may aid the explorationist in discovering this important seismic interval. Seismic and well log attribute values were cross plotted and have revealed associations between these data. Cross plots are accompanied by regression lines and R2 values which support our interpretations. Although reservoir quality dune complexes may be delineated, the Entrada/Curtis play appears to be mainly structural. The best producing wells in the survey are associated with structural or stratigraphic relief and the thickest Entrada/Curtis intervals. Structural and stratigraphic traps are not always associated with laterally extensive dune complexes. Time structure maps as well as isochron maps have proven useful in delineating the thickest and/or gas prone portions of the Entrada/Curtis interval as well as areas with structural and stratigraphic relief. We have observed that the zones of best production are associated with low gamma ray (40-60 API) values. These low values are associated with zones of high amplitude. Thus, max peak amplitude as a seismic attribute may delineate areas of higher sand content (i.e. dune complexes) whereas zones of low amplitude may represent areas of lower sand content (i.e. muddier interdune or tidal flat facies). Lack of significant average porosity does not seem to be related to a lack of production. In fact, the best producing wells have been drilled in Entrada/Curtis intervals where average porosity is near 4 %. There are however zones within the upper portion of the Entrada/Curtis that are 40 ft. (12.2 m) thick and have porosities between 14% and 20%. By combining derived attribute maps with observed cross plot relationships, it appears that the best producing intervals within the Entrada/Curtis are those associated with high amplitudes, API values from 40-60 and structural relief.