Approved for public release; distribution is unlimited / This thesis explores the hardware requirements of a local area network and then constructs a multiuser software library package for Turkish Battleships. The software implementation is designed as an expandable package so that future requirements can be met. The software package consists of three major parts. These are Personnel Eval­uations, Combat Information Center and Damage Control. Listings of the programs developed are presented, as well as instructions for their effective use. It is concluded that a PC Local Area network with the proper library programs is feasible for Turkish Battle Ships' computing requirements. / http://archive.org/details/microcomputerapp00gule / Lieutenant Junior Grade, Turkish Navy

"Submitted in partial fulfillment of the requirements for the degree of Master of Business Administration from the Naval Postgraduate School, June 2009." / Advisor(s): Euske, K. J. ; Wagner, Brett. "June 2009." "MBA professional report"--Cover. Description based on title screen as viewed on July 14, 2009. DTIC Identifiers: Arliegh Burke Class Destroyer, process improvement, shipboard analysis. Author(s) subject terms: Phased Replacement, Arliegh Burke Class Destroyer, Damage Control, Process Improvement, DDGRON, CNSF, COMNAVSURFOR, AFMP Includes bibliographical references (p. 59). Also available in print.

The eukaryotic cell cycle is governed by molecular checkpoints that ensure genomic integrity and the faithful transmission of chromosomes to daughter cells. They inhibit the cycle until conditions prevail that guarantee accurate DNA duplication and chromosome segregation. Two major mechanisms are the ‘spindle assembly checkpoint’ and the ‘DNA damage checkpoint’. During pro-metaphase, the spindle checkpoint monitors the orientation process of chromatid pairs on the bipolar microtubule array nucleated by spindle pole bodies. In the yeasts Schizosaccharomyces pombe and Saccharomyces cerevisiae, six proteins are at the heart of spindle checkpoint function: Mad1, Mad2, Mad3, Bub1, Bub3 and Mph1/Mps1. The formation of spindle checkpoint complexes signals the presence of incorrect spindle microtubule attachments to kinetochores. These complexes cooperate to suppress the activity of the anaphase promoting complex (APC) and inhibit the onset of anaphase. By isolating these distinct complexes and analysing their composition by mass-spectrometry (MS) this work revealed several intriguing disparities between the two yeast species, and the way in which the Bub and Mad proteins cooperate to achieve inhibition. The ‘mitotic checkpoint complex’, which in S.cerevisiae consists of Mad2, Mad3, Bub3 and the APC activator Cdc20, was found to lack Bub3 in S.pombe. The S.pombe complex was shown to interact with the APC, but no stable interaction was found to be required in S.cerevisiae cells. And whereas Bub1 and Bub3 were found to form a complex with Mad1 in S.cerevisiae, in S.pombe they were shown to associate with Mad3 to form the ‘BUB+ spindle checkpoint complex’. In addition, MS analysis uncovered TAPAS: a novel S.pombe complex that was found to interact with the BUB+ complex and revealed to consist of Tfg3, Abo1 (gene product of SPAC31G5.19), Pob3 and Spt16. TAPAS mutant cells were shown to lose viability as a result of genotoxic stress, a phenotype that was surprisingly shared with bub1Δ and bub1kd ‘kinase dead’ mutants. Sensitivity of cells deficient in TAPAS or Bub1 did not appear to be due to the loss of DNA damage checkpoint or DNA replication checkpoint functions. Further examination revealed that Bub1 functions in the repair of DNA double strand breaks. Taken together, this work demonstrates that even though the molecular components of the spindle checkpoint pathway are conserved, their regulatory connections have to some extent diverged through molecular evolution. This process not only rewired, but entwined two molecular processes that together safeguard the genetic heritage of cells.

Thesis (M.S. in Systems Engineering)--Naval Postgraduate School, September 2003. / Thesis advisor(s): Gurminder Singh, Perry McDowell. Includes bibliographical references (p. 55-56). Also available online.

Thesis (M.S.)--Massachusetts Institute of Technology, 2002. / Includes bibliographical references (p. 51.52). Also available online.

Försvarsmaktens sjukvårdsorganisation var under det kalla kriget och invasionsförsvarets dagar anpassad och dimensionerad för att kunna omhänderta tusentals skadade per dygn. Sedan 1990-talet har Försvarsmaktens inriktning fokuserat på internationella insatser. I kombination med förändringar inom det medicinska området, hotbilder, skadepanorama och folkopinionen har detta lett till nya förmågor inom den militära sjukvården. Sedan en tid har Försvarsmaktens inriktning ändrats till ett mer nationellt fokus. Vad har då hänt med sjukvårdsförmågorna? Denna uppsats använder sig av Moshe Kress teorier presenterade i boken ”Operational Logistics - The Art and Science of Sustaining Military Operations” för att göra en analys av de förmågor Försvarsmaktens insatsorganisation har idag. Kress teorier används även för att analysera vilka förmågor som krävs för att uppnå en lägsta acceptabel sjukvårdsnivå på Medical Treatment and Evacuation och vilka förmågor som bör ingå i Försvarsmaktens framtida insatsorganisation. I uppsatsen konstateras att den framtida insatsorganisationen bör innehålla förmågor för Damage Control, både sett ur ett operationellt perspektiv och ur ett medicinskt perspektiv.

In early 1994 the United States Department of Agriculture’s Animal Damage Control agency implemented a directive providing guidance to help avoid competition between themselves and private businesses, known as Wildlife Control Operators (WCOs) engaging in similar work. Nearly two decades later some WCOs still complain about having to compete with the Animal Damage Control agency, now named Wildlife Services. Other businesses report enjoying a cooperative relationship with the agency. I analyzed four policies that regulate competition between Wildlife Services and WCOs and found that there is a good amount of guidance given to Wildlife Services in regards to their competitive relationship with WCOs. These guidelines do not carry the force of law, however, and are subject to change and deletion. I conducted interviews with representatives from the WCO community and Wildlife Services and found that the top four factors contributing to conflict are an overlap in similar services, agency advantages, money and pricing, and policy. The top four factors contributing to cooperation were cooperative work, communication, clarified roles, and training and education. Working to decrease the conflict factors and emphasize the cooperative factors will lead to a better relationship between Wildlife Services and WCOs.

An inductive learning method is analyzed for use in on-line control. The controller has the benefit of being designed without a system model and is able to adapt itself to varying system parameters. Numerical experiments were performed with the Quantized Inductive Learning (QIL) algorithm, an extension of ‘Boxes’, on simple linear systems and a simulated simply supported aluminum beam. Concurrent with the simulations, a theoretical analysis of the learning mechanism was generated. The evaluation of several issues with the algorithm (performance indices, sampling periods, and level of quantizations) were studied to validate the theory. A comparison with state feedback was used to compare the effectiveness of this method with traditional model-based approaches. The results indicate the method learns a control function which moves the system from an arbitrary initial condition to equilibrium or rejects a sinusoidal disturbance. In both cases, the control is learned in absence of an a priori system model. / Master of Science

This study reveals how the Pacific war changed at Coral Sea and Midway due to a little known but important cadre of sailors on USS Yorktown (CV5). Those US victories resulted from not only clever code breakers and courageous airmen but equally from the determined Damage Control (DC) crews aboard Yorktown. DC crews were the ship’s first responders. They fought fires, kept power and propulsion operable, controlled the ship’s stability, and patched her flight deck to keep aircraft flying. DC teams saved Yorktown multiple times, and their story is memorable for their contributions at Coral Sea and Midway. Without DC efforts, CV5 would not have participated in the battle of Midway. Without Yorktown, the commitment of only two American carriers (with one being virtually inexperienced) against four Japanese carriers with their skilled airmen would have yielded disaster for the United States at Midway instead of victory.

A mail survey of randomly selected stratified U.S. households assessed general attitudes toward wildlife and specific concerns about wildlife damage management and the federal Animal Damage Control program. Respondents strongly supported federal government's role in ensuring public safety , engaging in public education, and continuing research into nonlethal control methods. Weaker support was found for lethal control of predators and crop depredators, and financial compensation for losses due to wildlife activities was generally opposed. Lethal methods of control were generally considered to be inhumane and nonlethal methods humane. When asked to rank the importance of factors to be considered when selecting management methods, II human safety ranked highest followed by animal suffering, effectiveness, environmental impacts, severity of problem, and ability to target the specific problem animal. The lowest ranked factor was public opinion. Considered as a whole, results suggest that U.S. citizens want a role in wildlife damage policy formation but respect wildlife professionals ' judgment in specific management situations. This study also assessed attitudes and beliefs about wildlife damage management (WDM) activities and federal government agencies ' roles in carrying out those activities. Multiple regression analysis was used to determine if variables such as environmental attitude, wildlife experience, and sociodemographic characteristics explained levels of support for WDM activities and the importance of the federal government's role . Respondents generally support WDM operations. Differences in respondents' general environmental attitudes and enjoyment of hunting accounted for most of the variation in their attitudes toward WDM practices. Independent variables that most influenced perceived importance of federal involvement in WDM were sex , age, education, and general environmental attitudes.