Thesis (M.S.)--University of Michigan, 1994. / Includes bibliographical references.

Thesis (Ph. D.)--University of Washington, 1994. / Vita. Includes bibliographical references (leaves [159]-165).

Thesis (M.S.)--University of Michigan, 1994. / Includes bibliographical references.

Thesis (M.S.)--University of Florida, 2003. / Title from title page of source document. Includes vita. Includes bibliographical references.

Thesis (Ph. D.)--University of Washington, 1999. / Vita. Includes bibliographical references (leaves 109-117).

Thesis (Ph. D.)--State University of New York at Binghamton, Decker School of Nursing, 2005. / Includes bibliographical references.

The effect of CRT on incidence of AF development in patients with severe HF was explored by comparing 36 patients with conventional indication for the CRT to 36 HF patients without CRT, matched for age, sex and LV systolic function (Publication 5). After a follow up of 3 years, the annual incidence of AF in the CRT group was 2.8%, which was significantly lower than the control group (10.2%). Moreover, the echocardiographic benefit by CRT was compared between these 36 patients with SR and 15 patients with persistent AF. The results showed that the echocardiographic response was similar between the two groups. These findings suggested that CRT may have the potential to reduce AF burden in patients with severe HF and that patients with persistent AF may also benefit from CRT. / The objective of the study (Publication 1) was to assess the feasibility of using non-contact LV mapping to delineate the LV endocardial activation pattern in 7 HF patients in NYHA class III, with low LVEF and wide QRS complex (>120ms). Non-contact mapping was safely performed and there were two endocardial conduction patterns identified, namely homogenous (Type I) and conduction block (Type II). The second part of the study (Publication 2) was to determine the implication of these two distinct activation patterns to echocardiographic and clinical response to CRT. 23 patients in NYHA class III, with LVEF <35% and QRS duration >120ms were recruited in this study. 15 patients had Type II pattern and 8 Type I. The QRS duration between the two types of conduction patterns were comparable. Patients with Type II pattern had a more favourable echocardiographic and clinical response to CRT than those with Type I. It was concluded that, despite the similar QRS duration between the two types of LV endocardial activation patterns, patients with Type II pattern had a more favourable response to CRT. / The significance of baseline renal function in CRT was assessed in 85 consecutive patients with conventional indication for the CRT (Publication 7). There was no significant relationship between baseline renal function and significant LV reverse remodeling after CRT, suggesting baseline renal insufficiency probably would not affect the response to CRT. (Abstract shortened by UMI.) / This study (Publication 3) was to determine the effect of CRT in patients with narrow QRS complex and evidence of mechanical dyssynchrony as determined by TDI. 51 patients in NYHA class III or IV, with LV ejection fraction <35%, and QRS duration <120ms were recruited for the CRT. The effect of the device therapy on LV systolic function in this cohort was compared to 51 patients who fulfilled the current criteria with wide QRS complex. CRT significantly improved the LV systolic function, NYHA class and exercise capacity in those with narrow complex to a similar extent in those with wide complex. With co-existing mechanical dyssynchrony determined by TDI, patients in both narrow and wide QRS complex groups showed more favourable response to CRT than those without significant mechanical dyssynchrony. This confirmed that QRS was a poor marker of mechanical dyssynchrony and the current selection criteria are probably not adequate to include more potential responders to the therapy. / This study (Publication 4) was to determine the role of optimal medical therapy in CRT recipients before implantation. The echocardiographic and clinical effect of CRT in 30 patients without the optimal combination of ACEi or ARB and beta-blockers was compared to 30 patients matched for age, sex, NYHA class and HF etiology. Patients with optimal medical therapy had significantly better echocardiographic and clinical response to CRT. The results confirmed that optimal medical therapy is necessary to achieve maximal response by CRT. / This study (Publication 6) was to determine if patients with moderate LV systolic function and wide QRS complex would benefit from the CRT. Significant improvement in LV systolic function was observed in 15 patients with LVEF between 35 and 45%, NYHA class III and QRS duration >120ms after CRT, suggesting that presence of LV systolic dysfunction and cardiac dyssynchrony may be the major determining factors for favourable CRT response. Therefore, patients with less advanced HF may also benefit from the CRT. / "May 2007." / Adviser: Yu Cheuk Man. / Source: Dissertation Abstracts International, Volume: 69-08, Section: B, page: 4657. / Thesis (M.D.)--Chinese University of Hong Kong, 2007. / Includes bibliographical references (p. 133-151). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. [Ann Arbor, MI] : ProQuest Information and Learning, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / School code: 1307.

Background: The ICD controls the heart rhythm and reacts to serious heart rhythm abnormalities and trigger, if necessary, a defibrillation to restore the heart to normal rhythm. Living with an ICD can provide major changes in everyday life. Nurse´s important role regards to provide relevant patient education to include promoting the health and quality of life (QOL) for these individuals. Purpose: To describe QOL for people living with an ICD, from a gender and age perspective, and to examine the included articles selection strategy and research group. Method: The result of this descriptive literature review compiled from eleven quantitative scientific articles, sought in PubMed and Scopus. Main Results: Women reported lower QOL then men linked to impaired mental, physical and social function. Also a greater concern and anxiety were found in women. Mental illness affected mainly young people, who also experienced a lower acceptance to the device than older ICD- receivers. Older people reported less concern that the ICD would deliver a shock. However, a reduced QOL related to higher incidence of physical impairment, were noticed in the elderly ICD- receivers compared to the younger. Four articles specified their selection strategy. All reported the number of participants and how many were men and women. The age range of participants was specified in five articles. Conclusion: Impacts on QOL could be discerned to different gender and ages. These findings confirmed the need for health professionals to access more holistic patient- education programs that focus not only on the technical aspects of living with an ICD but more on the individual impact. / Bakgrund: En ICD kontrollerar hjärtrytmen, reagerar på allvarliga hjärtrytmrubbningar och utlöser vid behov en defibrillering för att återställa normal hjärtrytm. Att leva med en ICD kan innebära stora omställningar i det vardagliga livet. Sjuksköterskan har en betydande roll i omvårdnaden kring dessa personer där bland annat relevant patientutbildning är viktig för att främja personers hälsa och livskvalitet. Syfte: Syftet med denna litteraturstudie var att beskriva livskvaliteten hos personer som lever med en implanterbar defibrillator (ICD), ur ett köns- och åldersperspektiv, samt att granska de inkluderade artiklarnas urvalsstrategi och undersökningsgrupp. Metod: Denna beskrivande litteraturstudies resultat sammanställdes utifrån elva granskade artiklar av kvantitativ ansats, eftersökta i databaserna PubMed och Scopus. Huvudresultat: Kvinnor rapporterade lägre livskvalitet än männen kopplat till nedsatt mental, fysisk och social funktion. Även en ökad oro och ångest förekom hos kvinnor. Psykisk ohälsa utvecklades främst hos yngre, vilka också upplevde lägre acceptans till enheten än äldre ICD- bärare vilket påverkade livskvaliteten. Äldre personer rapporterade mindre oro över att ICD:n skulle defibrillera. Dock sågs en nedsatt livskvalitet relaterat till högre förekomst av fysisk nedsättning i större grad hos äldre än yngre ICD- bärare. Fyra av resultatartiklarna angav använd urvalsstrategi. Samtliga redogjorde för antalet deltagare och hur många som var män respektive kvinnor. Åldersspannet mellan deltagarna angavs i fem artiklar. Slutsats: Olika inverkan på livskvaliteten kunde skönjas både mellan kön och olika åldrar. Dessa fynd bekräftade behovet av att sjukvårdspersonal behöver få tillgång till mer holistiska patientutbildningsprogram som inte enbart fokuserar på de tekniska aspekterna av att leva med en ICD.

Thesis (M.S.)--University of Michigan, 2006. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 66-80).

Thesis (M.S.)--University of Michigan, 2006. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 66-80).