Submitted by PPG Gerontologia Biom?dica (geronbio@pucrs.br) on 2017-08-17T20:10:44Z No. of bitstreams: 1 SGNAOLIN_VANESSA_TESE.pdf: 5164818 bytes, checksum: 7903e0d0cab4f6b2f39cb20c4d8baac0 (MD5) / Rejected by Caroline Xavier (caroline.xavier@pucrs.br), reason: Devolvido devido ? falta de capa institucional no arquivo pdf. on 2017-08-21T12:33:45Z (GMT) / Submitted by PPG Gerontologia Biom?dica (geronbio@pucrs.br) on 2017-08-23T13:11:03Z No. of bitstreams: 1 SGNAOLIN_VANESSA_TESE.pdf: 5199437 bytes, checksum: b8092c8a0353302df374eed961532c1c (MD5) / Approved for entry into archive by Caroline Xavier (caroline.xavier@pucrs.br) on 2017-08-24T11:59:43Z (GMT) No. of bitstreams: 1 SGNAOLIN_VANESSA_TESE.pdf: 5199437 bytes, checksum: b8092c8a0353302df374eed961532c1c (MD5) / Made available in DSpace on 2017-08-24T12:05:38Z (GMT). No. of bitstreams: 1 SGNAOLIN_VANESSA_TESE.pdf: 5199437 bytes, checksum: b8092c8a0353302df374eed961532c1c (MD5) Previous issue date: 2017-04-28 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / This study aims to describe the medications used by people aged 55 years and over enrolled in the ?Programa de Envelhecimento Cerebral? (PENCE) of the Family Health Strategy of Porto Alegre. It will also describe among these patients the occurrence of polypharmacy, the use of potentially inappropriate medications and its association with patients? socioeconomic, lifestyle and health variables, especially the signs and symptoms of depression and cognitive deficit. A cross-sectional population-based study conducted from January 2013 to December 2015, approved by the Research Ethics Committee of PUCRS (n? 826.858). The prevalence of polypharmacy was reported in 35.7% of the population and was the most common drug amount of all age groups, including the younger individuals (55-59 years) (28.1%). After adjustment for socioeconomic and health variables, women (OR 2.46; 95% CI 1.71-3.53), 75-79 years (OR 3.13; 95% CI 1.68-5.83), 1-3 years of study (OR 2.57; 95% CI 1.43-4.59), ex-smokers (OR 1.89; 95% CI 1.29-2.78), poor or very poor self-perceived health (OR 6.43; 95% CI 3.20-12.90), chronic conditions (cardiovascular-related) and depression symptoms were strongly associated with polypharmacy. The prevalence of PIM in the total population was 65.4%, representing a common finding in all age groups, including younger individuals (55-59 years) (60.0%). Former smokers (OR 1.06; 95% CI 1.00-1.12) and current smokers (OR 1.10; 95% CI 1.01-1.18), regular self-perception of health (OR 1.08; 95% CI 1.02-1.15), use three or four medications (OR 1.88; 95% CI 1.65-2.15), and individuals with signs and symptoms of cognitive deficit (OR 1.14; 95% CI 1.03-1.26) and depression (OR 1.12; 95% CI 1.04-1.21) were significantly associated with PIM. Polypharmacy (OR 2.80; 95% CI 2.48-3.16) had the strongest association. Polypharmacy and MPI are prevalent in middle-aged individuals, a population that is poorly researched, and the elderly. The present study proposed an advance in pharmacoepidemiological studies, analyzing some gaps in the literature related to middle-aged adults with unfavorable socioeconomic characteristics, such as low income and schooling. / Este estudo tem por objetivo descrever os medicamentos utilizados por pessoas com 55 anos ou mais, cadastradas no Programa de Envelhecimento Cerebral (PENCE) da Estrat?gia Sa?de da Fam?lia de Porto Alegre, a ocorr?ncia de polifarm?cia, o uso de medicamentos potencialmente inapropriados e a associa??o com vari?veis socioecon?micas, h?bitos de vida e sa?de, principalmente os sinais e sintomas de depress?o e de d?ficit cognitivo. Estudo transversal de base populacional, realizado entre janeiro de 2013 a dezembro de 2015, aprovado pelo Comit? de ?tica em Pesquisa da PUCRS (n? 826.858). A preval?ncia de polifarm?cia na popula??o total foi de 35,7%, representando um achado comum a todas as faixas et?rias, incluindo os indiv?duos mais jovens (55-59 anos) (28,1%). Ap?s o ajuste para as vari?veis socioecon?micas e de sa?de, as mulheres (OR 2,46; IC 95% 1,71-3,53) e os indiv?duos com 75-79 anos (OR 3,13; IC 95% 1,68-5,83), 1-3 anos de estudo (OR 2,57; IC 95% 1,43-4,59), ex-fumantes (OR 1,89; IC 95% 1,29-2,78), com pior autopercep??o de sa?de (OR 6,43; IC 95% 3,20-12,90), com doen?as cr?nicas (principalmente as cardiovasculares) e com sintomas depressivos foram fortemente associados ? polifarm?cia. A preval?ncia de PIM na popula??o total foi de 65,4%, representando um achado comum a todas as faixas et?rias, incluindo os indiv?duos mais jovens (55-59 anos) (60,0%). Os ex-fumantes (OR 1,06; IC 95% 1,00-1,12) ou atuais (OR 1,10; IC 95% 1,01-1,18), com autopercep??o de sa?de regular (OR 1,08; IC 95% 1,02-1,15), que faziam uso de tr?s ou quatro medicamentos (OR 1,88; IC 95% 1,65-2,15) e com sinais e sintomas de d?ficit cognitivo (OR 1,14; IC 95% 1,03-1,26) e depress?o (OR 1,12; IC 95% 1,04-1,21) foram significativamente associados com o maior consumo de MPI, sendo a polifarm?cia (OR 2,80; IC 95% 2,48-3,16) a vari?vel com a mais forte rela??o. Polifarm?cia e MPI s?o prevalentes em indiv?duos de meia-idade, uma popula??o que ? pouco pesquisada, e em idosos. O presente estudo prop?s um avan?o nos estudos farmacoepidemiol?gicos, analisando algumas lacunas na literatura relacionada aos adultos de meia-idade com caracter?sticas socioecon?micas desfavor?veis, como baixas renda e escolaridade.

Submitted by SBI Biblioteca Digital (sbi.bibliotecadigital@puc-campinas.edu.br) on 2017-04-28T13:57:07Z No. of bitstreams: 1 CARLA FABIANA CARLETTI PESSOTTI.pdf: 1686396 bytes, checksum: cae4805c98f9d020da8253219f182a5e (MD5) / Made available in DSpace on 2017-04-28T13:57:08Z (GMT). No. of bitstreams: 1 CARLA FABIANA CARLETTI PESSOTTI.pdf: 1686396 bytes, checksum: cae4805c98f9d020da8253219f182a5e (MD5) Previous issue date: 2017-02-07 / Introduction: The longevity of the population results in a natural increase in the prevalence of diseases associated with aging, such as dementias, according to the current classification of DSM 5 (2013); dementias are in the Major Cognitive Disorder category; Occur in several pathological conditions, has characteristic the multiple development of cognitive deficits with impairments in basic and instrumental activities of daily living (AIVD/AVD), and specific care is required. In Brazil, caring for family/caregivers is common. The objective of this study was to describe the quality of life and the burden of family/caregivers of patients with dementia; analyze and compare the relationships between quality of life and the caregiver's burden. Procedures: 50 family/caregivers (GFC) and 50 patients with dementia (GDM) corresponding to family/caregivers were studied. In the GFC were evaluated sociodemographic aspects, quality of life, burden, depressive symptoms, religiosity index and resilience through the Qvd-DA instruments; Burden Interviw, BDI, PDUREL and Resilience Scale. In the GDM, sociodemographic, cognitive, neuropsychiatric and AIVD/AVD aspects were evaluated through the MEEM, INP, Semantic Verbal Fluency Test, Clock Drawing Test and DAD. The data were analyzed, related and compared between GFC, GDM, GDA and GNDA. Statistical tests were used with significance level p <0.05. Results: GFC predominated in the female gender (88%), mainly daughters (54%) and wives (32%), most married, with a mean age between 50 and 60 years and 8 years of schooling, years and 19 hours per day on average. GDM had a homogeneous distribution between genders, with a predominance of AD (68%), married (44%) and widowers (52%), above 70 years of age (78%), 82% of the patients had some kind of income. The GFC presented moderate burden, without depressive symptoms, high intrinsic religiosity index with daily practices of individual religious rituals and regular attendance to religious institutions, high perception of quality of life and high resilience index. Regarding severity of cognitive and neuropsychiatric impairment, GDA patients presented better performance than GNDA patients. Conclusion: The task of caring for patients with dementia is costly; the findings suggest that family/caregivers adapt to the situation they have experienced; they have shown moderate burden; minimal depressive symptoms; engagement in religious practices; high perception of quality of life and high resilience response to different situations. Family/caregivers with depressive symptoms presented greater perception of burden, lower resilience response, greater perception of quality of life impairment and greater intrinsic religiosity. Those who had greater resilience responses had a lower occurrence of depressive symptoms, a lower perception of burden, and a higher perception of a better quality of life. This data indicates that caregivers with resilience responses have fewer depressive symptoms. / Introdu??o: A longevidade da popula??o traz como decorr?ncia natural o aumento na preval?ncia de doen?as associadas ao envelhecimento como as dem?ncias, de acordo com a classifica??o atual do DSM 5 (2013), as dem?ncias est?o na categoria Transtorno Cognitivo Maior, ? uma s?ndrome que pode ocorrer em diversas condi??es patol?gicas, tem como caracter?stica o desenvolvimento m?ltiplo de d?ficits cognitivos com preju?zos em atividades b?sicas e instrumentais da vida di?ria (AIVD/AVD), sendo necess?rios cuidados espec?ficos. No Brasil ? comum os cuidados por familiares/cuidadores. O objetivo deste estudo foi descrever qualidade de vida e sobrecarga de familiares/cuidadores de pacientes com dem?ncia; analisar e comparar as rela??es entre qualidade de vida e sobrecarga do cuidador. Casu?stica e procedimentos: Foram estudados 50 familiares/cuidadores (GFC) e 50 pacientes com dem?ncia (GDM) correspondentes aos familiares/cuidadores. No GFC foram avaliados aspectos sociodemogr?ficos, qualidade de vida, sobrecarga, sintomas depressivos, ?ndice de religiosidade e resili?ncia atrav?s dos instrumentos Qvd-DA; Burden Interviw, BDI, PDUREL e Escala de Resili?ncia. No GDM foram avaliados aspectos sociodemogr?ficos, cognitivos, neuropsiqui?tricos e AIVD/AVD atrav?s dos instrumentos MEEM, INP, Teste de Flu?ncia Verbal Sem?ntica, Teste do Desenho do Rel?gio e DAD. Os dados foram analisados, relacionados e comparados entre os GFC, GDM, GDA e GNDA. Foram utilizados testes estat?sticos com n?vel de signific?ncia p< 0,05. Resultados: GFC predominou o g?nero feminino (88%), principalmente filhas (54%) e esposas (32%), a maioria casada, com idade m?dia entre 50 e 60 anos e com 8 anos de escolaridade, tarefa de cuidar h? 4 anos e 19 horas di?rias em m?dia. GDM houve distribui??o homog?nea entre g?neros, acima dos 70 anos (78%) com predom?nio na DA (68%), casados (44%) e vi?vos (52%), 82% dos pacientes possu?am algum tipo de renda. GFC apresentou sobrecarga moderada, sem sintomas depressivos, elevado ?ndice de religiosidade intr?nseca com praticas di?rias de rituais religiosos individuais e frequ?ncia regular a institui??es religiosas, elevada percep??o de qualidade de vida e alto ?ndice de resili?ncia. Quanto ? gravidade do comprometimento cognitivo e neuropsiqui?trico, os pacientes do GDA apresentaram melhor desempenho do que pacientes do GNDA. Conclus?o: A tarefa de cuidados ? pacientes com dem?ncia ? onerosa, os achados sugerem adapta??o dos familiares/cuidadores ? situa??o vivenciada, demonstraram sobrecarga moderada; sintomas depressivos m?nimos; engajamento em pr?ticas religiosas; elevada percep??o de qualidade de vida e elevada resposta de resili?ncia frente ?s diversas situa??es. Familiares/cuidadores com sintomas depressivos apresentaram maior percep??o de sobrecarga, menor resposta de resili?ncia, maior percep??o de comprometimento da qualidade de vida e maior religiosidade intr?nseca. Aqueles que possu?am maiores respostas de resili?ncia, apresentaram menor ocorr?ncia de sintomas depressivos, menor percep??o de sobrecarga e conseq?ente maior percep??o de melhor qualidade de vida. Esse dado indica que cuidadores com respostas de resili?ncia apresentam menos sintomas depressivos.

Made available in DSpace on 2014-12-17T14:13:32Z (GMT). No. of bitstreams: 1 MarcioLTA_Tese.pdf: 1453040 bytes, checksum: 7c0ed7c44a56eb54d2170012eedbfa04 (MD5) Previous issue date: 2009-11-27 / The imprecision of the frontier that separates those cognitive deficits inherent to the human physiological aging process from those which represent the early signs of nervous system degenerative pathologies ,very prevalent among the elderly, has brought attention to the need of studies aiming to establish clinical and/or laboratorial criteria to allow this differentiation. Elderly people living in poor and developing countries are frequently exposed to precarious socioeconomic conditions which facilitate the development of an array of pathologies which have metabolic and nutritional dysfunctions as the established or proposed etiological agents. The levels of certain micronutrients, such as the vitamins B12 and B9 (folic acid), and of some intermediary metabolites, such as homocysteine are being thought of as etiological factors and/or as biological markers of a group of alterations which affect the normal functioning of the nervous system with important reflexes upon cognitive performance. This study aims to investigate the influence of homocysteine, B12 vitamin and folic acid levels on the cognitive performance of the low income elderly population. This transversal study took place in Natal, Rio Grande do Norte State, Brazil, and involved 205 dwelling elderly people, users of the Programa de Sa?de da Fam?lia, a public healthcare program, maintained by the city s health authorities. A multidimensional questionnaire was used to assess the socio-demographic aspects and the overall health and nutrition conditions. The cognitive performance was measured by the use of the Portuguese version of the Mini Mental State Exam (MMSE). The serum levels of homocysteine, B12 vitamin and folic acid were determined by chemiluminescence. The association between the socio-demographic and serum levels of Hcy, B12 vitamin and folic acid was determined by multiple linear regression. Serum levels higher than 13.5 &#956;mol/l, indicative of hyperhomocysteinemia (HHcy), were found on 25.4% of the sample, being more prevalent in men (p<0.05). Deficitary levels of folic acid (<5ng/mol) and of B12 vitamin (<193 pg/ml) were found on 3.9% and 10.2% of the sample respectively. A negative correlation was found between cognitive performance with both age and HHcy and a positive correlation was found between cognitive performance and schooling. The isolated HHcy R2 values were an explanation to only 4% of the variance of the MMSE scores. However, when associated with schooling and age, this model explains about 25% of this association / A imprecis?o da fronteira que separa os d?ficits pr?prios do processo de envelhecimento fisiol?gico humano daqueles que representam os sinais precoces das patologias degenerativas de grande preval?ncia entre idosos, tem chamado a aten??o para a necessidade da produ??o de estudos voltados para o estabelecimento crit?rios cl?nicos e/ou laboratoriais que permitam essa diferencia??o. Idosos de popula??es de pa?ses pobres e/ou em desenvolvimento s?o freq?entemente expostos a condi??es socioecon?micas prec?rias prop?cias ao desenvolvimento de um conjunto de patologias, disfun??es metab?licas e nutricionais. Os n?veis de determinados micronutrientes e de alguns metab?litos intermedi?rios v?m sendo vistos como fatores etiol?gicos e como marcadores biol?gicos de um conjunto de altera??es que afetam a fun??o normal do sistema nervoso com reflexos importantes sobre o desempenho cognitivo. N?veis elevados de homociste?na (Hcy) e d?ficits nutricionais e /ou metab?licos da vitamina B12 e B9 (?cido f?lico) t?m sido apontados como preditores e/ou como fatores etiol?gicos de altera??es cognitivas. O objetivo desse estudo foi avaliar a influ?ncia dos n?veis de homociste?na, Vitamina B12 e ?cido f?lico no desempenho cognitivo de idosos de baixa renda. Este estudo transversal desenvolvido em Natal, Rio Grande do Norte, Brasil, incluiu 205 idosos n?o institucionalizados atendidos pelo Programa de Sa?de da Fam?lia da Secretaria Municipal de Sa?de do munic?pio. Um question?rio multidimensional foi utilizado para avaliar os aspectos sociodemogr?ficos e as condi??es gerais de sa?de e nutri??o. O desempenho cognitivo foi aferido utilizando-se a vers?o em portugu?s do Mini-Exame do Estado Mental (MEEM). Os n?veis s?ricos de homociste?na, Vitamina B12 e ?cido f?lico foram determinados por quimioluminesc?ncia. A associa??o entre as vari?veis sociodemogr?ficas e os n?veis s?ricos de Hcy Vitamina B12 e ?cido f?lico foi determinada atrav?s de regress?o linear m?ltipla. Valores s?ricos acima de 13,5 &#956;mol/l indicativos de hiperhomocisteinemia (HHcy) foram encontrados em 25,4% da amostra sendo mais prevalente em homens (p<0,05). N?veis deficit?rios de ?cido f?lico (<5ng/ml) e de Vitamina B12 (<193 pg/ml) foram encontrados em 3,9% e 10,2% dos indiv?duos respectivamente. O desempenho cognitivo mostrou uma correla??o negativa com a idade e a HHcy e positiva com a escolaridade. Os valores R2 da HHcy isolada explicaram apenas 4% da vari?ncia da pontua??o do MEEM. Contudo, quando associada escolaridade e idade, este modelo explica aproximadamente 25% desta associa??o.

Submitted by SBI Biblioteca Digital (sbi.bibliotecadigital@puc-campinas.edu.br) on 2017-04-04T11:51:15Z No. of bitstreams: 1 TAMIRES BARBOSA NASCIMENTO DOS SANTOS.pdf: 5285149 bytes, checksum: d224eb611ad840d86fa9cacfe3b79d1a (MD5) / Made available in DSpace on 2017-04-04T11:51:15Z (GMT). No. of bitstreams: 1 TAMIRES BARBOSA NASCIMENTO DOS SANTOS.pdf: 5285149 bytes, checksum: d224eb611ad840d86fa9cacfe3b79d1a (MD5) Previous issue date: 2017-02-02 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / The increase of the population's average age, there was a prevalence increment on the chronic nerological disorders, degenerative such as the Alzheimer's Disease (AD). The deepening on the knowledge of the processes of lifestyle, regarding the nutritional state and its relations with the cognition are important for the guidance and conducting of the elderly people. This study aimed to analyze the nutritional status of elderly patients with AD and its relationship with the clinical aspects, neurocognitive, behavioral and lifestyle. 43 elderlies from the Clinical Neurology Ambulatory of the Celso Pierro Hospital and Maternity (PUCCampinas) were evaluated with the diagnosis of light, moderate and severe AD, according to the Clinical Dementia Rating (CDR) and 51 controls matched by age, gender, schooling and socioeconomic level, whith no history of cognitive decline. The procedures used were: clinical evaluation, mental State mini-exam, simple drawing memory, verbal fluency, clock drawing, functional ability, neuropsychiatric inventory (NPI), CDR, socioeconomic evaluation, physical and social activity (International Questionnaire of Physical Activity - IQPA short version), Mini Nutritional Assessment (MNA), Body mass Index (BMI), Waist circumference (WC), Arm Circumference (AC), Calf Circumference (CC), Triciptal Cutaneous Fold (TCF), Subscapular cutaneous fold (SCF), Muscular Arm circumference (MAC), Corrected Arm Muscle Area (CAMA), Thumb Adductor Muscle (TAM), Palmar Holding Force (PHF) and Bioelectric Impedance. Comparison were made between Alzheimer's Disease Group (ADG) and Control Group (CG) with sociodemographic aspects, lifestyle, cognitive, MNA, Nutritional indicators and nutritional indicators by gender Comparisons were made between CG and AD stages according to the CDR with nutritional variables, It were also performed correlations between PHF with anthropometric variables on the ADG and CG and between cognitive and anthropometric variables on the ADG. With suitable statistical tests the situation and level of significance of 5% in all cases. It was noticed that the ADG develops less social activity and has a smaller relationship network, less physically active, and has poor performance in Daily life activities, mostly in instrumental activities. GDA showed malnutrition with a decrease in total food intake and higher daily intake of some foods on the MNA. Among genders, woman showed diferences in most anthropometric measurements with lower values in the ADG. In the comparison between CG and fazes of ADG there were differences in some measures with lower values in the severe ADG, and higher in the CG. In the comparison between CG and ADG, CG versus light and moderate ADG versus severe ADG there was a difference for some anthropometric measurements. There were no differences between Light and Moderate stages. The Lean Mass (LM) composition measurements were lower in the ADG. No difference was seen on the WC and reactance comparison. There were correlations between PHF and anthropometric variables in the ADG but not between nutritional variables with socioeconomic aspects, behavioral, NPI, social and physical activities. The findings suggests a significant association between social and leisure activities during the eld and a lower dementia risk. In the MNA the lowest score indicates greater deterioration of mental state. As per the feeding, it was noticed that, possibly, ADG feeds with lower amount and higher quality, suggesting a better selection of food by the caregiver. The authors reports a significant difference between BMI in AD phases, with reduction in BMI at the severe stage compared to light and moderate. In the study, there was a greater presence of elderly individuals at malnutrition risk in the AD group when compared to the CG, suggesting that the malnutrition is a factor of risk to the dementia progression. The nutritionals variables were progressively more committed with the advancement of cognitive deficits, since there was a LM reduction trend with the AD progression, more evident in the transition from moderate to severe. / Com o aumento da idade m?dia da popula??o houve incremento de preval?ncia de afec??es neurol?gicas cr?nicas, degenerativas, como a Doen?a de Alzheimer (DA). O aprofundamento do conhecimento dos processos do estilo de vida no que se refere ao estado nutricional e de suas rela??es com a cogni??o s?o de import?ncia para orienta??o e conduta desses idosos. O objetivo desse trabalho foi analisar o estado nutricional de idosos com DA e sua rela??o com aspectos cl?nicos, neurocognitivos, comportamentais e de estilo de vida. Foram avaliados 43 idosos procedentes do ambulat?rio de Neurologia Cl?nica do Hospital e Maternidade Celso Pierro (PUC-Campinas) com diagn?stico de DA leve, moderado e grave, segundo o Clinical Dementia Rating (CDR) e 51 controles pareados por idade, g?nero, escolaridade e n?vel socioecon?mico, sem hist?ria de decl?nio cognitivo. Os procedimentos foram avalia??o cl?nica, Mini-Exame do estado mental, mem?ria do desenho simples, Flu?ncia Verbal, desenho do rel?gio, capacidade funcional, Invent?rio Neuropsiqui?trico (INP), CDR, avalia??o socioecon?mica, atividade f?sica (Question?rio Internacional de Atividade F?sica ? IPAQ vers?o curta) e sociais, Mini Avalia??o Nutricional (MAN), ?ndice de Massa Corp?rea (IMC), Circunfer?ncia da Cintura (CC), Circunfer?ncia do Bra?o (CB), Circunfer?ncia da Panturrilha (CP), Dobra Cut?nea Tricipital (DCT), Dobra Cut?nea Subescapular (DCSE), Circunfer?ncia Muscular do Bra?o (CMB), ?rea Muscular do Bra?o corrigida (AMBc), M?sculo Adutor do Polegar (MAP), For?a de Preens?o Palmar (FPP) e Imped?ncia Bioel?trica. Foi realizada a compara??o entre Grupo Doen?a de Alzheimer (GDA) e Grupo Controle (GC) com aspectos sociodemogr?ficos, estilo de vida, cognitivos, comportamentais, MAN, indicadores nutricionais e indicadores nutricionais por g?nero. Foram feitas compara??es entre GC e est?gios da DA de acordo com CDR com as vari?veis nutricionais, tamb?m foram realizadas correla??es entre FPP com vari?veis antropom?tricas no GDA e GC e entre vari?veis cognitivas e antropom?tricas no GDA. Com testes estat?sticos adequados a situa??o e n?vel de signific?ncia de 5% em todos os casos. Foi observado que o GDA desenvolve menos atividade social e tem rede de relacionamento menor, ? fisicamente menos ativo e tem desempenho inferior nas Atividades de Vida Di?ria, principalmente nas atividades instrumentais. O GDA apresentou desnutri??o com diminui??o da ingest?o alimentar total e maior ingest?o di?ria de alguns alimentos, na MAN. Entre os g?neros, as mulheres apresentaram diferen?a em mais medidas antropom?tricas, com valores menores no GDA. Na compara??o entre GC e fases do GDA, houve diferen?a em algumas medidas com valores menores no GDA grave e maior no GC. Na compara??o entre GC e GDA, GC versus GDA leve e moderado e GDA leve e moderado versus GDA grave houve diferen?a para algumas medidas antropom?tricas. N?o houve diferen?a entre os est?gios leve e moderado. As medidas de composi??o de Massa Magra (MM) foram menores no GDA. CC e Reat?ncia n?o apresentaram diferen?a em nenhuma compara??o. Houve correla??es entre FPP e vari?veis antropom?tricas nos GDA e n?o houve entre vari?veis nutricionais com aspectos socioecon?micos, comportamentais, INP, atividades sociais e f?sicas. Os achados da literatura sugerem uma associa??o significativa entre atividades sociais e de lazer durante a velhice e o menor risco de dem?ncia. Na MAN a menor pontua??o indica maior deteriora??o do estado mental. Quanto a alimenta??o, foi observado que possivelmente o GDA se alimenta com menor quantidade e maior qualidade, sugerindo uma melhor sele??o dos alimentos pelo cuidador. Os autores relatam diferen?a significativa entre IMC nas fases da DA, com redu??o no IMC no est?gio grave comparado ao leve e moderado. No estudo houve maior presen?a de idosos em risco de desnutri??o no grupo com DA quando comparados ao GC, sugerindo que a desnutri??o ? um fator de risco para a progress?o da dem?ncia. As vari?veis nutricionais foram progressivamente mais comprometidas com o avan?ar dos d?ficits cognitivos, pois houve uma tend?ncia a redu??o de MM com a progress?o da DA, sendo mais evidente na transi??o da fase moderada para o grave.