IMRT uses non-uniform beam intensities within a radiation field to provide patient-specific dose shaping, resulting in a dose distribution that conforms tightly to the planning target volume (PTV). Unavoidable geometric uncertainty arising from patient repositioning and internal organ motion can lead to lower conformality index (CI), a decrease in tumor control probability (TCP) and an increase in normal tissue complication probability (NTCP). The CI of the IMRT plan depends heavily on steep dose gradients between the PTV and organ at risk (OAR). Geometric uncertainties reduce the planned dose gradients and result in a less steep or “blurred” dose gradient. The blurred dose gradients can be maximized by constraining the dose objective function in the static IMRT plan or by reducing geometric uncertainty during treatment with corrective verification imaging. Internal organ motion and setup error were evaluated simultaneously for 118 individual patients with implanted fiducials and MV electronic portal imaging (EPI). The Gaussian PDF is patient specific and group standard deviation (SD) should not be used for accurate treatment planning for individual patients. Frequent verification imaging should be employed in situations where geometric uncertainties are expected. The dose distribution including geometric uncertainties was determined from integration of the convolution of the static dose gradient with the PDF. Local maximum dose gradient (LMDG) was determined via optimization of dose objective function by manually adjusting DVH control points or selecting beam numbers and directions during IMRT treatment planning. EUDf is a useful QA parameter for interpreting the biological impact of geometric uncertainties on the static dose distribution. The EUDf has been used as the basis for the time-course NTCP evaluation in the thesis. Relative NTCP values are useful for comparative QA checking by normalizing known complications (e.g. reported in the RTOG studies) to specific DVH control points. For prostate cancer patients, rectal complications were evaluated from specific RTOG clinical trials and detailed evaluation of the treatment techniques. Treatment plans that did not meet DVH constraints represented additional complication risk. Geometric uncertainties improved or worsened rectal NTCP depending on individual internal organ motion within patient.

IMRT uses non-uniform beam intensities within a radiation field to provide patient-specific dose shaping, resulting in a dose distribution that conforms tightly to the planning target volume (PTV). Unavoidable geometric uncertainty arising from patient repositioning and internal organ motion can lead to lower conformality index (CI), a decrease in tumor control probability (TCP) and an increase in normal tissue complication probability (NTCP). The CI of the IMRT plan depends heavily on steep dose gradients between the PTV and organ at risk (OAR). Geometric uncertainties reduce the planned dose gradients and result in a less steep or “blurred” dose gradient. The blurred dose gradients can be maximized by constraining the dose objective function in the static IMRT plan or by reducing geometric uncertainty during treatment with corrective verification imaging. Internal organ motion and setup error were evaluated simultaneously for 118 individual patients with implanted fiducials and MV electronic portal imaging (EPI). The Gaussian PDF is patient specific and group standard deviation (SD) should not be used for accurate treatment planning for individual patients. Frequent verification imaging should be employed in situations where geometric uncertainties are expected. The dose distribution including geometric uncertainties was determined from integration of the convolution of the static dose gradient with the PDF. Local maximum dose gradient (LMDG) was determined via optimization of dose objective function by manually adjusting DVH control points or selecting beam numbers and directions during IMRT treatment planning. EUDf is a useful QA parameter for interpreting the biological impact of geometric uncertainties on the static dose distribution. The EUDf has been used as the basis for the time-course NTCP evaluation in the thesis. Relative NTCP values are useful for comparative QA checking by normalizing known complications (e.g. reported in the RTOG studies) to specific DVH control points. For prostate cancer patients, rectal complications were evaluated from specific RTOG clinical trials and detailed evaluation of the treatment techniques. Treatment plans that did not meet DVH constraints represented additional complication risk. Geometric uncertainties improved or worsened rectal NTCP depending on individual internal organ motion within patient.

Carbon dioxide (CO2) is the most important component of Greenhouse Gas (GHG) that causes global warming and sea-level rising. Thermal power plants dominate electric power generation in the world, and has been reported to be the major contributor of CO2 emission. To prevent the related global warming caused by GHG emission, carbon quota trading is implemented and becomes a gradually arising market. This thesis proposed a research focused on the relationship between the carbon trading scheme and dynamic economic dispatch (DED) problem for the public utility. A model of the carbon trading market was investigated and introduced into DED problem incorporating wind and solar power plant. A refined particle swarm optimization (PSO) algorithm, PSO with time-varying acceleration coefficients (PSO-TVAC), is applied to determine the DED strategy with the incorporation of independent power providers (IPPs) and green power plant. The model of the carbon trading was considered in the DED problem. Carbon reduction is treated as the inner-cost of utility, and the fictitious carbon quotas can be resold to the market, while the energy shortage can be satisfied by purchasing quotas from the market. In order to avoid premature convergence of the original PSO, the PSO-TVAC method is introduced to improve the searching efficiency.

Un des dangers chimiques les plus importants relevés par l'OMS concerne la contamination des céréales par les mycotoxines et notamment les aflatoxines et les fumonisines. La réglementation recommande des contaminations maximales d'aflatoxines dans les céréales inférieures à 20 mg/kg ; cependant on relève couramment des taux supérieurs à 200 mg/kg dans le maïs au Mexique. Bien qu'il ait été évalué que le processus de nixtamalisation détruit plus de 90 % des fumonisines et de 80 à 95 % des aflatoxines, le taux résiduel peut encore être élevé : certaines publications rapportent des concentrations jusqu'à 100 mg/kg dans les tortillas, ce qui représente un risque avéré vue la grande consommation de tortillas au Mexique (325g/j). Le JECFA (2001) a établi une dose maximale acceptable de 2μg/kg pc/j pour la fumonisine et recommande de réduire l'exposition aux aflatoxines au plus faible niveau possible en considérant que le seuil de 1 ng/kg pc/j ne devrait pas être atteint. Au cours de cette thèse 3 enquêtes aléatoires et représentatives ont été menées dans 40 tortillerias de la ville de Veracruz. La consommation de maïs de la population a été évaluée à partir d'un questionnaire de consommation. L'analyse des mycotoxines a été réalisée par HPLC-FD par utilisation de colonnes à immunoaffinité selon la réglementation européenne (CIRAD-Montpellier). L'analyse des données obtenues a été effectuée selon une méthode probabiliste permettant de construire une fonction de distribution de probabilités à partir de la méthode de Monte Carlo (UBO). La représentativité de la population a été validée à partir d'évaluation de quotas de population après échantillonnage aléatoire initial. La contamination des tortillas a été mesurée à 0.54-1.96 mg/kg pour les aflatoxines et à 65-136 mg/kg pour les fumonisines. La consommation moyenne de tortillas a été mesurée à 148 g de maïs par jour. L'exposition de la population aux aflatoxines apparaît alors comprise entre 0,94 et 3,14 ng/kg pc/j et celle aux fumonisines entre 146 et 315 ng/kg pc/j. Les échantillons les plus contaminés proviennent des tortillerias réalisant elles-mêmes leur procédure de nixtamalisation. L'analyse des résultats montre que 60 % de la population de Veracruz serait à risque selon les préconisations du JECFA. L'exposition aux fumonisines atteint 5 % de la dose maximale acceptable, du fait d'une relativement faible contamination du maïs à cette mycotoxine. Les résultats montrent donc un risque sanitaire pour la population de la ville de Veracruz. Une extension de ce travail à la totalité de l’Etat de Veracruz, incluant la population rurale, devrait être menée du fait du risque probablement accru de cette dernière catégorie de population en lien avec sa plus forte consommation de maïs. / One of the chemical hazards that WHO has reported more frequently is cereals contamination with mycotoxins, mainly aflatoxins and fumonisins. NOM-188-SSA1-2002 establishes that aflatoxin concentration in grain should not exceed 20 mg kg-1 ; however, there are reported concentrations > 200 mg kg-1 in maize. Although it has been documented that nixtamalizacion removes more than 90% of fumonisins and between 80 and 95% of aflatoxins, the residual amount could be important, finding reports concentrations higher than 100 mg kg-1 of aflatoxin in tortilla, representing a risk due to the high consumption of tortillas in Mexico (325 g d-1). The JECFA (2001) establishes a maximum intake of 2 mg kg-1 pc d-1 for fumonisin and aflatoxin recommends reducing “as low as reasonably achievable” levels. 3 random and representative sampling in Veracruz city, each in 40 tortillerias, were made. Corn intake and weight of the population were estimated using a consumption questionnaire. Mycotoxins analysis were performed by HPLC-FD using immunoaffinity columns according to European standard UNE-EN ISO 14123 : 2008 for aflatoxins and UNE-EN 13585 : 2002 for fumonisin in the CIRAD (Montpellier, France). Statistical analysis were performed under a probabilistic approach in collaboration with the University of Bretagne Occidentale (Brest, France), building probability density function (PDF) and using the Monte Carlo method. PDF parameters of the weight of the population was 74.15kg for men (which coincides with reported by CANAIVE) and 65.83kg for women ; the pollution aflatoxin tortilla was 0.54 – 1.96mg kg-1 and fumonisin from 65.46 – 136.00mg kg-1 ; the tortilla consumption was 148.3g of corn per person per day ; the daily intake of aflatoxins was 0.94 – 3.14ng kg-1 bw d-1 and fumonisin of 146.24 – 314.99ng kg-1 bw d-1. Samples with higher aflatoxin contamination came from tortillerias that make the nixtamalization in situ. In assessing exposure it was found that up to 60% of the population could be consuming more than the recommended by JECFA (2001) for aflatoxin dose (1ng kg-1 bw d-1). Exposure to fumonisins intake was < 5% due to low contamination by these mycotoxins. The results suggest that the population of the city of Veracruz could be in food risk by eating contaminated corn tortillas AFT. It is advisable to extend this study in rural communities, where risk factors could increase.

abstract: This thesis provides a cost to benefit assessment of the proposed next generation distribution system, the Future Renewable Electric Energy Distribution Management (FREEDM) system. In this thesis, a probabilistic study is conducted to determine the payback period for an investment made in the FREEDM distribution system. The stochastic study will help in performing a detailed analysis in estimating the probability density function and statistics associated with the payback period. This thesis also identifies several parameters associated with the FREEDM system, which are used in the cost benefit study to evaluate the investment and several direct and indirect benefits. Different topologies are selected to represent the FREEDM test bed. Considering the cost of high speed fault isolation devices, the topology design is selected based on the minimum number of fault isolation devices constrained by enhanced reliability. A case study is also performed to assess the economic impact of energy storage devices in the solid state transformers so that the fault isolation devices may be replaced by conventional circuit breakers. A reliability study is conducted on the FREEDM distribution system to examine the customer centric reliability index, System Average Interruption Frequency Index (SAIFI). It is observed that the SAIFI was close to 0.125 for the FREEDM distribution system. In addition, a comparison study is performed based on the SAIFI for a representative U.S. distribution system and the FREEDM distribution system. The payback period is also determined by adopting a theoretical approach and the results are compared with the Monte Carlo simulation outcomes to understand the variation in the payback period. It is observed that the payback period is close to 60 years but if an annual rebate is considered, the payback period reduces to 20 years. This shows that the FREEDM system has a significant potential which cannot be overlooked. Several direct and indirect benefits arising from the FREEDM system have also been discussed in this thesis. / Dissertation/Thesis / Masters Thesis Electrical Engineering 2016

Image enhancement improves an image appearance by increasing dominance of some features or by decreasing ambiguity between different regions of the image. Image enhancement techniques have been widely used in many applications of image processing where the subjective quality of images is important for human interpretation. In many cases, the images have lack of clarity and have some effects on images due to fog, low light and other daylight effects exist. So, the images which have these scenarios should be enhanced and made clear to recognize the objects clearly. Histogram-based image enhancement technique is mainly based on equalizing the histogram of the image and increasing the dynamic range corresponding to the image. The Histogram equalization algorithm was performed and tested using different images facing the low light, fog images and colour contrast and succeeded in obtaining enhanced images. This technique is implemented by averaging the histogram values as the probability density function. Initially, we have worked with the MATLAB code on Histogram Equalization and made changes to implement an Application Program Interface i.e., API using Xamarin software. The mobile application developed using Xamarin software works efficiently and has less execution time when compared to the application developed in Android Studio. Debugging of the application is successfully done in both Android and IOS versions. The focus of this thesis is to develop a mobile application on Image enhancement using Xamarin on low light, foggy images.

Multi-agent systems are extensively used in several applications. An important class of applications involves the optimal spatial distribution of a group of mobile robots on a given area, where the optimality refers to the assignment of subregions to the robots, in such a way that a suitable coverage metric is maximized. Typically the coverage metric encodes a risk distribution defined on the area, and a measure of the performance of individual robots with respect to points inside the region of interest. The coverage metric will be maximized when the set of mobile robots configure themselves as the centroids of the Voronoi tessellation dictated by the risk density. In this work we advance on this result by considering a generalized area control problem in which the coverage metric is non-autonomous, that coverage metric is time varying independently of the states of the robots. This generalization is motivated by the study of coverage control problems in which the coordinated motion of a set of mobile robots accounts for the kinematics of objects penetrating from the outside. Asymptotic convergence and optimality of the non-autonmous system are studied by means of Barbalat's Lemma, and connections with the kinematics of the moving intruders is established. Several numerical simulation results are used to illustrate theoretical predictions.

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No / The probability density and exceedance probability functions of the induced currents in a screened cable connecting two enclosures, resulting from the close. presence of single and multiple mobile phones working at 900 MHz, are investigated. The analysis of the problem is undertaken using the Method of Moments, but due to weak coupling, the impedance matrix was modified to reduce the memory and time requirements for the problem, to enable it to be executed multiple times. The empirical probability distribution functions (PDFs) and exceedance probabilities for the induced currents are presented. The form of the PDFs is seen to be quite well approximated by a log-normal distribution for a single source and by a Weibull distribution for multiple sources

Yes / This paper presents a new control strategy for stochastic distribution shape tracking regarding non-Gaussian stochastic non-linear systems. The objective can be summarised as adjusting the probability density function (PDF) of the system output to any given desired distribution. In order to achieve this objective, the system output PDF has first been formulated analytically, which is time-variant. Then, the PDF vectorisation has been implemented to simplify the model description. Using the vector-based representation, the system identification and control design have been performed to achieve the PDF tracking. In practice, the PDF evolution is difficult to implement in real-time, thus a data-driven extension has also been discussed in this paper, where the vector-based model can be obtained using kernel density estimation (KDE) with the real-time data. Furthermore, the stability of the presented control design has been analysed, which is validated by a numerical example. As an extension, the multi-output stochastic systems have also been discussed for joint PDF tracking using the proposed algorithm, and the perspectives of advanced controller have been discussed. The main contribution of this paper is to propose: (1) a new sampling-based PDF transformation to reduce the modelling complexity, (2) a data-driven approach for online implementation without model pre-training, and (3) a feasible framework to integrate the existing control methods. / This paper is partly supported by National Science Foundation of China under Grants (61603262 and 62073226), Liaoning Province Natural Science Joint Foundation in Key Areas (2019- KF-03-08), Natural Science Foundation of Liaoning Province (20180550418), Liaoning BaiQianWan Talents Program, i5 Intelligent Manufacturing Institute Fund of Shenyang Institute of Technology (i5201701), Central Government Guides Local Science and Technology Development Funds of Liaoning Province (2021JH6/10500137).