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M.Sc. (Med.), Epidemiology and Biostatistics, Faculty of Health Sciences, University of the Witwatersrand, 2009

No description available.

O presente estudo avaliou uma casuística constituída por 144 transplantes dentários autógenos realizados em 128 pacientes, submetidos a controles periódicos de 6 meses a 23 anos. O objetivo do trabalho foi avaliar a influência de fatores clínicos e radiográficos no índice de sucesso dos transplantes realizados. Clinicamente avaliou-se a alteração na coloração dentária, vitalidade pulpar, comprometimento periodontal, tipo dentário transplantado e sítio receptor. Radiograficamente foram avaliados a presença ou não de reabsorção radicular, anquilose dento-alveolar, alterações no compartimento pulpar, complementação do desenvolvimento radicular, presença de periapicopatia persistente e relação coroa/raiz. Os dados foram coletados, analisados e submetidos a cálculos estatísticos pertinentes. As reabsorções dentárias, a anquilose dentoalveolar, a proporção coroa/raiz, a presença de periapicopatia persistente, o desenvolvimento de bolsa periodontal profunda e a mobilidade dentária destacaram-se de forma significante estatisticamente P<0,05. O tipo dentário doador, o sítio receptor, as alterações na coloração dentária e o desenvolvimento radicular na época da cirurgia do transplante não alcançaram índices de significância relacionados ao insucesso dos casos. A presença de processos esclerosantes pulpares mostrou-se comum aos transplantes bem sucedidos de dentes com rizogênese incompleta. Estes achados contribuem para o desenvolvimento de um protocolo terapêutico bem fundamentado. / The present study examined a sample consisting of 144 autogenous dental transplants performed in 128 patients, subjected to periodic follow-up from 6 months to 23 years. The objective was to evaluate the influence of clinical and radiographic factors in the success rate of the performed transplants. Clinical evaluation aimed the change in tooth color, pulpal vitality, periodontal involvement, transplanted tooth type and recipient site. Radiographic evaluation aimed the presence or absence of root resorption, ankylosis, pulpal changes, complementation of the root development, presence of persistent periapical lesions and crown-root ratio. The data were collected, analyzed and submitted to the relevant statistical calculations. Tooth resorptions, ankylosis, crown to root proportion, presence of persistent periapical lesions, development of periodontal pocket depth and tooth mobility was highlighted as statistically significant P <0.05. The donor tooth type, the receptor site, changes in tooth color and root development at the time of the transplant surgery did not reach levels of significance related to the failure of the cases. The presence of pulpal sclerosis processes shown to be common to successful transplantation of teeth with incomplete root formation. These findings contribute to the development of a reliable therapeutic protocol.

Orientador: Wilson Roberto Poi / Coorientadora: Mirian Marubayashi Hidalgo / Banca: Celso Koogi Sonoda / Banca: Daniela Atili Brandini de Weert / Banca: Raquel Sano Suga Terada / Banca: Christine Men Martins / Resumo: Objetivo: Avaliar, o reparo pulpar diante de dois antibióticos de uso sistêmico, tetraciclina e amoxicilina, em casos de reposicionamento (luxação extrusiva) ou reimplante (avulsão) dentários imediatos em ratos. Material e Métodos: Incisivos centrais maxilares superiores de ratos foram luxados e reposicionados após 5 minutos (n=90) ou extraídos, imersos em soro fisiológico por 5min e reimplantados (n=90). Os grupos foram divididos em três subgrupos (n=30) conforme o antibiótico e o controle (soro fisiológico) administrado após o ato cirúrgico e até sete dias. Os animais foram eutanasiados após 7, 15 ou 30 dias. Cortes histológicos longitudinais foram corados com HE para análise histomorfológica da camada de odontoblastos, deposição de dentina reparativa, bainha epitelial de Hertwig mantida junto com o dente, necrose e infiltrado inflamatório periapical. Para a análise estatística, utilizaram-se os testes de Mann-Whitney, Kruskal-Wallis e de Dunns (p<0,05). Resultado: Verificou-se haver diferença estatisticamente significativa entre os grupos amoxicilina e tetraciclina apenas na deposição de dentina reparativa no terço médio aos 15 dias após a luxação extrusiva. Para avulsão, a diferença ocorreu entre esses mesmos grupos aos 7 dias (presença da camada de odontoblastos, necrose e infiltrado inflamatório) e aos 15 dias (presença de necrose). Adicionalmente, verificaram-se diferenças entre o uso da amoxicilina ao longo do tempo tanto na avulsão como na luxação. Conclusão: A avali... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Aim: To evaluate the pulp repair in the presence of two systemic antibiotics, tetracycline and amoxicillin, in cases of immediate dental repositioning (extrusive luxation) or replantation (avulsion), in rats. Material and Methods: Upper maxillary central incisors of rats were dislocated and repositioned after 5min (n = 90), or extracted, immersed in physiological solution for 5min, and reimplanted (n = 90). The groups were divided into three subgroups (n=30) according to the antibiotic or saline (control) administered after the surgery and up to seven days. The animals were euthanized after 7, 15 or 30 days. Longitudinal histological sections were stained with HE for histomorphological analysis of the odontoblast layer, reparative dentin deposition, Hertwig epithelial sheath maintained along with the tooth, necrosis, and periapical inflammatory infiltrate. For the statistical analysis the Mann-Whitney, Kruskal-Wallis e de Dunns (p<0,05). Results: There was a statistically significant difference between the amoxicillin and tetracycline groups only in the reparative dentin deposition in the middle third at 15 days after the extrusive luxation. For avulsion, the difference occurred between these same groups at 7 days (presence of odontoblasts layer, necrosis and inflammatory infiltrate) and at 15 days (presence of necrosis). Additionally, there were differences between the use of amoxicillin over time in both avulsion and luxation. Conclusion: Microscopic evaluation demonstrated... (Complete abstract click electronic access below) / Doutor

O presente estudo avaliou uma casuística constituída por 144 transplantes dentários autógenos realizados em 128 pacientes, submetidos a controles periódicos de 6 meses a 23 anos. O objetivo do trabalho foi avaliar a influência de fatores clínicos e radiográficos no índice de sucesso dos transplantes realizados. Clinicamente avaliou-se a alteração na coloração dentária, vitalidade pulpar, comprometimento periodontal, tipo dentário transplantado e sítio receptor. Radiograficamente foram avaliados a presença ou não de reabsorção radicular, anquilose dento-alveolar, alterações no compartimento pulpar, complementação do desenvolvimento radicular, presença de periapicopatia persistente e relação coroa/raiz. Os dados foram coletados, analisados e submetidos a cálculos estatísticos pertinentes. As reabsorções dentárias, a anquilose dentoalveolar, a proporção coroa/raiz, a presença de periapicopatia persistente, o desenvolvimento de bolsa periodontal profunda e a mobilidade dentária destacaram-se de forma significante estatisticamente P<0,05. O tipo dentário doador, o sítio receptor, as alterações na coloração dentária e o desenvolvimento radicular na época da cirurgia do transplante não alcançaram índices de significância relacionados ao insucesso dos casos. A presença de processos esclerosantes pulpares mostrou-se comum aos transplantes bem sucedidos de dentes com rizogênese incompleta. Estes achados contribuem para o desenvolvimento de um protocolo terapêutico bem fundamentado. / The present study examined a sample consisting of 144 autogenous dental transplants performed in 128 patients, subjected to periodic follow-up from 6 months to 23 years. The objective was to evaluate the influence of clinical and radiographic factors in the success rate of the performed transplants. Clinical evaluation aimed the change in tooth color, pulpal vitality, periodontal involvement, transplanted tooth type and recipient site. Radiographic evaluation aimed the presence or absence of root resorption, ankylosis, pulpal changes, complementation of the root development, presence of persistent periapical lesions and crown-root ratio. The data were collected, analyzed and submitted to the relevant statistical calculations. Tooth resorptions, ankylosis, crown to root proportion, presence of persistent periapical lesions, development of periodontal pocket depth and tooth mobility was highlighted as statistically significant P <0.05. The donor tooth type, the receptor site, changes in tooth color and root development at the time of the transplant surgery did not reach levels of significance related to the failure of the cases. The presence of pulpal sclerosis processes shown to be common to successful transplantation of teeth with incomplete root formation. These findings contribute to the development of a reliable therapeutic protocol.

Objective: To assess the knowledge of Fire Services staff regarding the management of tooth avulsion. Methods: A web-based survey was designed and sent to Fire Services staff of two local communities. Results: Of all 340 respondents, 42% previously experienced case(s) of tooth avulsion. Only 7% of the study participants had complete knowledge about tooth avulsion. The relationship between the knowledge and information previously received was statistically significant. 84% of the respondents were interested in receiving further information about tooth avulsion and on-line education was selected as the most preferred method. Conclusion: The study demonstrates the lack of adequate knowledge and training among Fire Services personnel about emergency management of avulsed tooth injuries. Fire services personnel would benefit from training regarding the management of tooth avulsion injuries, given the high likelihood of them being the first responders and encountering such emergencies.

Objective: To assess the knowledge of Fire Services staff regarding the management of tooth avulsion. Methods: A web-based survey was designed and sent to Fire Services staff of two local communities. Results: Of all 340 respondents, 42% previously experienced case(s) of tooth avulsion. Only 7% of the study participants had complete knowledge about tooth avulsion. The relationship between the knowledge and information previously received was statistically significant. 84% of the respondents were interested in receiving further information about tooth avulsion and on-line education was selected as the most preferred method. Conclusion: The study demonstrates the lack of adequate knowledge and training among Fire Services personnel about emergency management of avulsed tooth injuries. Fire services personnel would benefit from training regarding the management of tooth avulsion injuries, given the high likelihood of them being the first responders and encountering such emergencies.

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