A literature study was undertaken to investigate the experience of loss and grief in the different developmental stages, as well as to identify characteristics of loss and grief in the young child. Guidelines have been compiled on how to handle loss and grief in young children. The empirical study comprised of workshop presentations. Through these presentations it was also determined as to whether parents and children would benefit from such workshops, as well as if the information regarding loss and grief addressed the parents’ needs. The empirical study found that parents are ignorant about loss and grief in the young child. However, all the parents had questions about loss and grief. After the workshops parents indicated that they became aware of positive changes in their own behaviour towards their children, and also in that of their children. One of the biggest problems in handling loss and grief in the young child seemed to be open and honest communication. / Educational Studies / M.Ed. (Guidance and Counseling)

A literature study was undertaken to investigate the experience of loss and grief in the different developmental stages, as well as to identify characteristics of loss and grief in the young child. Guidelines have been compiled on how to handle loss and grief in young children. The empirical study comprised of workshop presentations. Through these presentations it was also determined as to whether parents and children would benefit from such workshops, as well as if the information regarding loss and grief addressed the parents’ needs. The empirical study found that parents are ignorant about loss and grief in the young child. However, all the parents had questions about loss and grief. After the workshops parents indicated that they became aware of positive changes in their own behaviour towards their children, and also in that of their children. One of the biggest problems in handling loss and grief in the young child seemed to be open and honest communication. / Educational Studies / M.Ed. (Guidance and Counseling)

The work is focused on spring application of plant growth regulators and the operating conditions of agricultural society Kosova Hora, as Preparations were applied during the growth phase stands 32-33 BBCH scale, with 2 types of varieties - a line of hybrid canola varieties. 3 preparations were evaluated (Galleko, Toprex, Caryx) and one untreated area for control of the comparison of products. During the vegetation period were gradually on individual plots monitored the main elements of the plant yield (number of plants, number of pods, HTS, the number of branches). After harvesting canola yield was determined at the experimental plot. Results showed a positive reaction to stand on the treated area CARYX product. Attainment and income (4, 53 t / ha) on the experimental plot was achieved on a plot of hybrid rape. Difference treated variants compared to the control side were 0, 28 t / ha. This result is not statistically provable. The results are largely influenced the course of weather throughout the growing season. For better statistical power experiment would be preferable to multi attempts.

The diploma thesis observed the indicators of growth in individual developmental stages of our native crayfish (Astacus astacus, Austropotamobius torrentium, Astacus leptodactylus) and non-native crayfish (Pacifastacus leniusculus, Orconectes limosus) under experimental conditions. The next aim of work was to describe the time of hatching of these species, the moulting interval, the frequency of moulting and increase after individual moulting during the first vegetation season in two different temperatures (15{$\rm^o$}C a 21{$\rm^o$}C).

No description available.

京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第22886号 / 医博第4680号 / 新制||医||1048(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 髙橋 良輔, 教授 井上 治久, 教授 伊佐 正 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

This thesis maps trends and development of partner cohabitation in relation to social policy changes. Marriage has a rich history and its form and nature has changed several times in the past. In the last sixty years, the divorce rate has risen, women have become more emancipated and their participation in the labour market. Unmarried cohabitation is similar to marriage which it also usually precedes. This type of partner cohabitation is currently more common and it sometimes replaces marriage completely. The theoretical part of this thesis also describes the founding of a family, its function and history, because starting a family is closely related to marriage and unmarried cohabitation. The remainder of the theoretical part is dedicated to social and family policy, which is characterized in greater detail, regarding its concepts, goals and tools, together with family support systems and measures. The goal of this thesis was to map preferred forms of partner cohabitation at various stages of social policy development in the Czech Republic and to determine the influence of individual social policy measures on population development in the context of marriage, birth or divorce rates in the short and long term. Two hypotheses related to the goals of this thesis have been established. Hypothesis no. 1: The concept of marriage has been more important for women than for men at all stages of social policy development. Hypothesis no. 2: University-educated individuals prefer marriage more than those with elementary education. The first part of the research results is a comparative analysis of available secondary resources relating to certain development stages of social policy in our country. The second part of the research was conducted in the form of a pilot study, using the quantitative method on questionnaires. Results indicate that significant change in the material conditions of families with children has positive effect on population growth. Women used to link marriage to motherhood and to greater certainty while raising children. The number of marriages among university graduates is increasing. This has also been caused by the higher number of people with university education. This trend started in the early 90s. Respondents with university degrees expressed the opinion that the main reason to form a marriage is having children, yet they do not consider it as important as those without university education.

La fusion ETO2-GLIS2, récemment découverte dans les leucémies aiguës mégacaryoblastiques (LAM-M7) et d’autres sous-types de leucémies aiguës myéloïdes (LAM), est associée à un mauvais pronostic.L’objectif de ce travail a été d’étudier les mécanismes mis en jeu par ETO2-GLIS2 dans les cellules leucémiques ainsi que son association spécifique avec les leucémies pédiatriques. Par des analyses moléculaires, nous avons montré que ETO2-GLIS2 se fixe à l’ADN via la partie GLIS2 ainsi que via ETO2 et ses partenaires (incluant GATA, ETS, RUNX) entrainant ainsi une forte dérégulation de l’expression de facteurs de transcription incluant ERG et GATA1.J’ai développé un modèle murin inductible de la fusion ETO2-GLIS2 qui reproduit efficacement les différentes hémopathies observées chez l’Homme. Ce modèle a permis d’observer l’influence du stade développemental (hématopoïèse fœtale vs. adulte) et du type cellulaire (cellule souche hématopoïétique vs. Progéniteur multipotent) sur le phénotype et l’agressivité des leucémies. De plus, la dérégulation transcriptionnelle imposée par ETO2-GLIS2 est différente en fonction du contexte cellulaire. Dans l’ensemble ces résultats indiquent que la fusion ETO2-GLIS2 est suffisante pour induire une leucémie dont le phénotype et l’agressivité sont dépendants du contexte cellulaire dans lequel l’oncogène est introduit. Ils indiquent également que les changements cellulaires et moléculaires au cours du développement sont à l’origine de la forte prévalence des LAM-M7 chez les enfants. / The ETO2-GLIS2 fusion, recently discovered in acute megakaryoblastic leukemia (AMKL) and other subtypes of acute myeloid leukemia (AML), is associated with poor prognosis.The aim of this work was to study the mechanisms involved in ETO2-GLIS2 leukemic cells and its specific association with pediatric leukemia.Molecular analyses have shown that ETO2-GLIS2 binds to DNA via the GLIS2 moiety as well as via ETO2 and its partners (including GATA, ETS, RUNX), leading to a strong dysregulation of the expression of transcription factors including ERG and GATA1.I have developed an inducible murine model of ETO2-GLIS2 fusion that efficiently reproduces the different hematopoietic malignancies observed in humans. We were able to observe the influence of developmental stage (fetal vs. Adulte hematopoiesis) and cell type (hematopoietic stem cell vs. Multipotant progenitor) on the phenotype and aggressiveness of leukemia. In addition, the transcriptional dysregulation imposed by ETO2-GLIS2 was different according to the cellular context.Overall, these results indicate that ETO2-GLIS2 fusion is sufficient to induce leukemia whose phenotype and aggressiveness are dependent on the cellular context in which the oncogene is expressed. They also indicate that cellular and molecular changes during development are responsible for the high prevalence of AMKL in children.

Submitted by Maria Beatriz Vieira (mbeatriz.vieira@gmail.com) on 2017-04-25T16:00:16Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_samantha_rigo_segalin.pdf: 851707 bytes, checksum: 2bcbe9a904cb9861fc51a1a437d8f4fd (MD5) / Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-04-25T17:21:42Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_samantha_rigo_segalin.pdf: 851707 bytes, checksum: 2bcbe9a904cb9861fc51a1a437d8f4fd (MD5) / Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2017-04-25T17:24:27Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_samantha_rigo_segalin.pdf: 851707 bytes, checksum: 2bcbe9a904cb9861fc51a1a437d8f4fd (MD5) / Made available in DSpace on 2017-04-25T17:24:39Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_samantha_rigo_segalin.pdf: 851707 bytes, checksum: 2bcbe9a904cb9861fc51a1a437d8f4fd (MD5) Previous issue date: 2015-08-31 / Sem bolsa / O estresse causado pelo alagamento interfere negativamente na fisiologia, crescimento e desenvolvimento das plantas, limitando, portanto, a produtividade das áreas tritícolas. As respostas das plantas de trigo (Triticum aestivum L.) submetidas ao alagamento ainda não são perfeitamente compreendidas. O melhor entendimento do mecanismo de crescimento em condições de privação de oxigênio pode contribuir para o adequado manejo das lavouras e detecção de possíveis problemas no desenvolvimento da cultura. Para testar a suscetibilidade ao encharcamento ao longo da ontogenia da cultura, os objetivos foram analisar o crescimento e a partição de assimilados das plantas de trigo submetidas a diferentes períodos de alagamento, bem como avaliar a expressão do vigor de sementes produzidas pelas plantas submetidas ao alagamento em pré e pós-antese. As plantas de trigo foram submetidas ao alagamento por três, quatro e cinco dias durante duas fases do ciclo de cultivo: elongamento do colmo e enchimento das sementes. Ao avaliar comparativamente o estresse negativo em condições de hipoxia nos estádios vegetativo e reprodutivo, utilizou-se o tempo médio de quatro dias de inundação para determinar a fase fenológica mais sensível ao alagamento. O alagamento afeta negativamente o crescimento de plantas de trigo, verificado pela redução da matéria seca total e da taxa de produção de matéria seca. A partição de matéria seca não mostra variações pronunciadas entre as estruturas da planta de trigo submetidas ao alagamento nos estádios vegetativo e na fase de enchimento da semente. O alagamento de plantas de trigo ocasiona redução no vigor de sementes. O estresse por alagamento no estádio vegetativo e reprodutivo em plantas de trigo causa redução de produtividade, pelo decréscimo do peso de mil sementes. / Waterlogging stress adversely modifies physiology, plant growth and plants development, limiting therefore, the wheat areas productivity. The Triticum aestivum L. plants responses subjected to flooding are not completely understood. A better understanding of growth mechanism under oxygen depletion conditions may contribute to suitable crops management and detect possible problems in the culture development. To assay the flooding susceptibility along the culture ontogeny, the aims were analyze the wheat plants growth and assimilated partition into different flooding periods as well evaluate the seed vigor expression produced by plants subject to waterlogging in pre and post-anthesis. The wheat plants were subjected to flooding for three, four and five days during two stages of the crop cycle: the stem elongation and filling of the seed. To quantify the negative stress under hypoxic conditions in vegetative or reproductive stages, were used a four days waterlogged time to determine which phenological stage were more sensitive to flooding. Flooding negatively affects the wheat plants growth, as verified by the reduction of total dry matter and dry matter production rate. The dry matter partition does not show pronounced variations among the wheat plant structures subjected to flooding in vegetative and seed filling stage. The wheat plants waterlogged causes reduction in seed vigor. Flooding stress in vegetative and reproductive stage of wheat plants cause yield reduction by decreasing the thousand grains weight.

Thesis entitled Diagnosis of children with different mother tongue in preschool age deals with the issue of diagnosis of children with different mother tongue in preschool age, specifically deals with approaches, methods and possibilities of diagnosing children with different mother tongue in preschool age. Thesis focuses on the diagnosis of the development of a child of preschool age, outlines the diagnosis of a child in kindergarten, and especially describes and charts the methods and procedures for diagnosing these children in pedagogical-psychological counseling. The aim of this thesis is to clarify these issues, describe the legislative basis for the education and support of children with different mother tongue in preschool age and the specifics of these children. The aim of the empirical part is to chart the process of diagnosing children with different mother tongue in preschool age by workers of pedagogical-psychological counseling in the capital city of Prague using semi- structured interviews. Specifically, which methods and procedures do workers use, whether they work with a special tool for these children, what is the cooperation between pedagogical-psychological counseling and other institutions, and whether do pedagogical- psychological counseling workers face difficulties in this...