Thesis (Ph.D.)--Electrical and Computer Engineering, Georgia Institute of Technology, 2008. / Committee Chair: Skrinjar, Oskar; Committee Member: Oshinski, John; Committee Member: Tannenbaum, Allen; Committee Member: Vela, Patricio; Committee Member: Yezzi, Anthony

Thesis (PhD)--Montana State University--Bozeman, 2009. / Typescript. Chairperson, Graduate Committee: Trevor Douglas. Includes bibliographical references (leaves 127-140).

Thesis (Ph.D)--Electrical and Computer Engineering, Georgia Institute of Technology, 2009. / Committee Chair: Oskar krinjar; Committee Member: Allen Tannenbaum; Committee Member: Anthony Yezzi; Committee Member: John Oshinski; Committee Member: Patricio Vela. Part of the SMARTech Electronic Thesis and Dissertation Collection.

Thesis (Ph. D.)--University of Texas at Austin, 1997. / Vita. Includes bibliographical references (leaves 188-199). Available also in a digital version from Dissertation Abstracts.

Thesis (Ph. D.)--Auburn University, 2009. / Abstract. Vita. Includes bibliographical references (p. 83-86).

Thesis (Ph.D.) - Carleton University, 2007. / Includes bibliographical references (p. 154-171). Also available in electronic format on the Internet.

Thesis (Ph. D.)--Duke University, 2007. / Includes bibliographical references.

Thesis (Ph. D.)--Biomedical Engineering, Georgia Institute of Technology, 2006. / Dr. X. Hu, Committee Member ; Dr. Al Merrill, Committee Member ; Dr. Niren Murthy, Committee Member ; Dr. Gang Bao, Committee Chair ; Dr. Nicholas Hud, Committee Member. Includes bibliographical references.

Thesis (Ph. D.)--University of Washington, 2007. / Vita. Includes bibliographical references (leaves 228-245).

Orientador: Leda Maria Pescinini Salzedas / Banca: Ana Maria Pires Soubhia / Banca: Ana Lucia Alvares Capelozza / Resumo: O consumo abusivo de álcool interfere no metabolismo ósseo podendo causar a osteoporose, e o fluoreto de sódio tem sido usado para reduzir o risco de fratura na osteoporose. Não há relatos do efeito sinérgico dessas substâncias no tecido ósseo. A densitometria óssea é um método preciso para avaliação do conteúdo mineral ósseo. O objetivo deste estudo foi realizar a análise densitométrica óssea em fêmur de rato submetidos ao consumo de fluoreto e ao consumo crônico de álcool com e sem consumo prévio de fluoreto. Os 105 ratos foram divididos em 5 grupos conforme a dieta líquida: água (Controle C) e fluoreto (Grupo F) "ad libitum" por um período de 90 dias; água (Grupo CA) e fluoreto (Grupo FA) por 30 dias antes do consumo de aguardente de cana (40o GL) em concentrações crescentes de 30% e 60% durante 20 dias, e pura por 40 dias até eutanásia do animal; água por 60 dias e a seguir fluoreto por 30 dias (Grupo CF). Os animais foram sacrificados após 3, 10 e 28 dias de completada a dieta, os fêmures esquerdos foram dissecados e submetidos à análise densitométrica no sistema DXA. Os valores obtidos de conteúdo de massa óssea (CMO) e densidade mineral óssea (DMO) foram submetidos à análise de variância e teste de Tukey para comparação entre os grupos, sendo verificada diferença estatística entre os grupos no CMO e DMO. A ordem decrescente de DMO foi: F, CF, C, FA, CA, sendo observada diferença estatística entre os grupos F e CA. O grupo F apresentou os maiores valores de CMO e DMO, e os grupos FA e CA apresentaram menores médias de CMO e DMO comparados aos C, F e CF. Podemos concluir que o uso de NaF de maneira prolongada aumenta a densidade óssea e que o uso crônico de álcool diminui os valores de CMO e DMO, mesmo com o uso prévio de NaF, sendo encontrado valores intermediários após consumo das duas substâncias. / Abstract: The abusive alcohol consumption intervenes with the bone metabolism being able to cause osteoporosis and the sodium fluorid has been used to reduce the risk of breaking in osteoporosis. There are not reports of the synergistic effect of such substances on bone tissue. The aim of this study was to analysis bone density in the rat femur submitted to the use of fluoride and the chronic consumption of alcohol with and without pre-fluoride. The 105 rats had been divided in 5 groups in agreement the liquid diet: water (Control C) and fluorid (Fluorid F) "ad libitum" for a period of 90 days; water (water and alcohol CA) and fluorid (fluorine and alcohol FA) per 30 days before the consumption of sugar cane brandy (40°GL) in increasing concentrations of 30% and 60% during 20 days, and pure for 40 days until euthanasia of the animal; water per 60 days and to follow fluorid per 30 days (fluorid 30 days CF). The animals were sacrificed after 3, 10 and 28 days of completion of the diet, the left femurs were dissected and submitted for analysis in the DXA standard system. The values obtained of bone mass content (BMC) and bone mineral density (BMD) were submitted to the analysis of variance and test Tukey for comparison between groups, and found statistical difference between the groups in the BMC and BMD. The order of decreasing BMD was: F, CF, C, FA, CA, and observed statistical difference between the groups F and CA. The group F presented the highest values of BMC and BMD, and the FA and CA groups had lower average BMC and BMD compared to C, F and CF. We can conclude that the use of NaF on a prolonged increases bone density and that the chronic use of alcohol lowers the values of BMC and BMD, even with the previous use of NaF, and intermediate values found after consumption of the both substances. / Mestre