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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

CHARACTERIZATION OF PHOSPHOINOSITIDE AND SPHINGOLIPID DOMAIN FORMATION IN MODEL MEMBRANES

Jiang, Zhiping 01 December 2010 (has links)
No description available.
2

Infrared Spectroscopic Characterization of Phosphoinositide Signaling Pathway Components

Isler, Yasmin Salah Blaih 14 July 2011 (has links)
No description available.
3

Induced shape changes in liquid crystal elastomers

Pevnyi, Mykhailo Y. 27 July 2015 (has links)
No description available.
4

Membrane properties of cholesterol analogs with an unbranched aliphatic side chain

Meyer, Thomas, Baek, Dong Jae, Bittman, Robert, Haralampiev, Ivan, Müller, Peter, Herrmann, Andreas, Huster, Daniel, Scheidt, Holger A. 07 December 2015 (has links) (PDF)
The interactions between cholesterol and other membrane molecules determine important membrane properties. It was shown that even small changes in the molecular structure of cholesterol have a crucial influence on these interactions. We recently reported that in addition to alterations in the tetracyclic ring structure, the iso-branched side chain of cholesterol also has a significant impact on membrane properties (Scheidt H. et al. 2013 Angew. Chem. Int. Ed. Engl. 52, 12848-12851). Here we used synthetic cholesterol analogs to investigate the influence of an unbranched aliphatic side chain of different length. The 2H NMR order parameter of the phospholipid chains and therefore the molecular packing of the phospholipid molecules shows a significant dependence on the sterol’s alkyl side chain length, while , membrane permeation studied by a dithionite ion permeation assay and lateral diffusion measured by 1H MAS pulsed field gradient NMR are less influenced. To achieve the same molecular packing effect similar to that of an iso-branched aliphatic side chain, a longer unbranched side chain (n-dodecyl instead of n-octyl) at C17 of cholesterol is required. Obviously, sterols having a branched iso- alkyl chain with two terminal methyl groups exhibit altered cholesterol-phospholipid-interactions compared to analogous molecules with a straight unbranched chain.
5

Kinetics of Domain Formation Processes in Lipid Membranes / Kinetik von Domänenformationsprozessen in Lipidmembranen

Seeger, Heiko 08 March 2006 (has links)
No description available.
6

Membrane properties of cholesterol analogs with an unbranched aliphatic side chain: Membrane properties of cholesterol analogs with an unbranchedaliphatic side chain

Meyer, Thomas, Baek, Dong Jae, Bittman, Robert, Haralampiev, Ivan, Müller, Peter, Herrmann, Andreas, Huster, Daniel, Scheidt, Holger A. January 2014 (has links)
The interactions between cholesterol and other membrane molecules determine important membrane properties. It was shown that even small changes in the molecular structure of cholesterol have a crucial influence on these interactions. We recently reported that in addition to alterations in the tetracyclic ring structure, the iso-branched side chain of cholesterol also has a significant impact on membrane properties (Scheidt H. et al. 2013 Angew. Chem. Int. Ed. Engl. 52, 12848-12851). Here we used synthetic cholesterol analogs to investigate the influence of an unbranched aliphatic side chain of different length. The 2H NMR order parameter of the phospholipid chains and therefore the molecular packing of the phospholipid molecules shows a significant dependence on the sterol’s alkyl side chain length, while , membrane permeation studied by a dithionite ion permeation assay and lateral diffusion measured by 1H MAS pulsed field gradient NMR are less influenced. To achieve the same molecular packing effect similar to that of an iso-branched aliphatic side chain, a longer unbranched side chain (n-dodecyl instead of n-octyl) at C17 of cholesterol is required. Obviously, sterols having a branched iso- alkyl chain with two terminal methyl groups exhibit altered cholesterol-phospholipid-interactions compared to analogous molecules with a straight unbranched chain.

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