Opioid drug related death is the topic of this thesis. Each of the published works submitted in this volume has investigated an aspect of opioid drug related death. The publications have been grouped into three sub-themes: i. Characteristics of opioid drug related deaths ii. Methadone-related deaths in and out of treatment iii. Improving the quality of treatment for opioid drug dependence: a focus on injectable opioid treatment The introduction and background (Chapter1) will briefly review-the-relevant literature on opioid drug death predating my own contribution to the field. The next chapter of the thesis, 'Publications' (Chapter 2), will comprise the body of published work being submitted for the degree of Doctor of Medicine. Each article is accompanied by text on the preceding page outlining my individual contribution to that research study. The thesis will conclude with a discussion of the published works (Discussion, Chapter 3) which summarises the chief findings and reflects on the international significance and impact of the work. Finally, the Conclusion (Chapter 4) will submit suggestions for areas of future research into opioid drug related death.

The European Monitoring Centre for Drugs and Drug Addiction reports that drug-related deaths have almost tripled in Sweden between year 2006 and 2015. The aim of this study is to elucidate in which ways drug-related mortality is produced and conceptualized as a problem within policy discourse by critically analyzing The National Board of Health and Welfare’s policy proposal “Nationellt utvecklingsarbete för att motverka narkotikarelaterad dödlighet” (2017). Using Bacchi’s poststructural approach to policy analysis “What’s the problem represented to be?”, two problem representations are identified, namely that drug-related mortality is conceptualized as a problem with drugs and drug use in general as well as a problem due to lack of knowledge and information. This is based on underlying assumptions that all illegal drug use is hazardous and that the solution to the drug problem can be obtained by objective knowledge production thus leaving both the practice of gaining knowledge as well as current Swedish drug laws unproblematized. The effects are, to name a few, that proposed policies mainly targets “all people who use drugs” with a focus on providing “more of the same” which in extension overrides the group of high-risk drug users along with a structural understanding of drug-related mortality.