Based on the acquisition trajectory, PROPELLER MRI repeatedly sampled the center k-space in every blade, which was used to provide most of the energy of an image. The purpose of view sharing PROPELLER is to improve the spatio-temporal resolution of dynamic imaging by reducing the acquisition time of single frame to that of single blade. With the center k-space provided by only one blade, which is called the target blade, the high spatial-frequency components were appropriately contributed by a set of neighboring blades with different rotation angles, leading to the high spatial resolution after reconstruction. In this study, a flow phantom experiment with the injection of T1-shortening Gd-DTPA solution was performed to exam the feasibility and accuracy of view-sharing PROPELLER. Furthermore, cardiac imaging of healthy volunteer obtained by the proposed technique was also done with ECG gating to test the image quality without any injection of contrast agent. The in-vivo experiment was done with and without breath holding. In addition to slight aliasing artifact due to insufficient FOV, no other artifact was observed.

Kranskärlssjukdom (CAD) är den ledande dödsorsaken. Sjukdomen startar med plackbildning i ett eller flera kranskärl, vilket kan leda till bröstsmärta samt andra symtom. Diagnostik av CAD inkluderar undersökningarna arbetsprov (AP) och myokardscintigrafi (MPI). Båda undersökningarnas prognostiska värde påverkas dock av parametrar som elektrokardiogram (EKG), EKG-triggning, Dukes löpbands index (DTS) och Metaboliska ekvivalenter (MET). Litteraturstudiens syfte var att jämföra den prognostiska prestandan hos AP jämfört med MPI. Detta genom att studera de nämnda parametrarnas prognostiska påverkan på respektive undersökning. De använda artiklarna uppfyllde samtliga inklusionskriterier: engelska, peer-reviewed samt etiskt godkänd eller inhämtat samtycke. Databasen Pubmed, snowballsmetod samt relaterade artiklar användes vid litteraturinsamlingen. Enligt resultatet ökar ovannämnda parametrar det prognostiska värdet hos både AP och MPI. Dock visades att patienter som uppnår olika MET samt DTS-värden bättre kan riskkategoriseras med MPI. Dessutom visades MPI kunna skilja de med sämre prognos bland patienter med positiva AP-resultat, men även bland de med negativa AP-resultat. Därmed drog författarna slutsatsen att MPI har ett ökat mervärde gällande prognostik hos patienter med CAD. Fler studier som samtidigt jämför AP och MPI behövs dock för en mer fullständig slutsats. / Coronary artery disease (CAD) is the leading cause of death. This disease starts with plaque buildup in one or more coronary vessels, which can lead to chest pain among other symptoms. Diagnostics include the exercise stress test (AP) and myocardial scintigraphy (MPI). The prognostic value of both examinations depends on parameters such as electrocardiogram (ECG), ECG-gating, Duke treadmill score (DTS) and Metabolic equivalents (MET). The purpose of this study was to compare the prognostic performance of AP with MPI, by studying the prognostic effect of the mentioned parameters in each study. The used articles met all inclusion criterias: English, peer-reviewed, and ethically accepted or obtained consent. Pubmed database, snowball method and related articles were used for literature collection. According to the results, the above-mentioned parameters increase the prognostic value of AP and MPI. However, patients achieving different MET and DTS scores are better categorized with MPI. MPI was shown to differentiate those with poorer prognosis among patients with positive AP-results and those with negative AP-results. The authors concluded that MPI has an added value regarding prognosis forpatients with CAD. However, more studies comparing AP and MPI at the same time are needed to obtain a more complete conclusion.