<p>Electrooculogram (EOG) data was used to develop, adjust and validate a method for drowsiness detection in drivers. The drowsiness detection was based on changes in blink behaviour and classification was made on a four graded scale. The purpose was to detect early signs of drowsiness in order to warn a driver. MATLAB was used for implementation. For adjustment and validatation, two different reference measures were used; driver reported ratings of drowsiness and an electroencephalogram (EEG) based scoring scale. A correspondence of 70 % was obtained between the program and the self ratings and 56 % between the program and the EEG based scoring scale. The results show a possibility to detect drowsiness by analyzing blink behaviour changes, but that inter-individual differences need to be considered. It is also difficult to find a comparable reference measure. The comparability of the blink based scale and the EEG based scale needs further investigation.</p>

Electrooculogram (EOG) data was used to develop, adjust and validate a method for drowsiness detection in drivers. The drowsiness detection was based on changes in blink behaviour and classification was made on a four graded scale. The purpose was to detect early signs of drowsiness in order to warn a driver. MATLAB was used for implementation. For adjustment and validatation, two different reference measures were used; driver reported ratings of drowsiness and an electroencephalogram (EEG) based scoring scale. A correspondence of 70 % was obtained between the program and the self ratings and 56 % between the program and the EEG based scoring scale. The results show a possibility to detect drowsiness by analyzing blink behaviour changes, but that inter-individual differences need to be considered. It is also difficult to find a comparable reference measure. The comparability of the blink based scale and the EEG based scale needs further investigation.

The aging brain is characterized by alteration in synaptic contacts, which leads to decline of motor and cognitive functions. These changes are reflected in the age related shifts in power spectrum of electroencephalogram (EEG) signals in both wakefulness and sleep. Various non-linear measures have been used to obtain more insights from EEG analysis compared to the conventional spectral analysis. In our study we used Sample Entropy to quantify regularity of the EEG signal. Because elderly subjects arouse from sleep more often than younger subjects, we hypothesized that Entropy of EEG signals from elderly subjects would be higher than that from middle aged subjects, within a sleep stage. We also hypothesized that the entropy increases during and following an arousal and does not return to background levels immediately after an arousal. Our results show that Sample Entropy varies systematically with sleep state in healthy middle-aged and elderly female subjects, reflecting the changing regularity in the EEG. Sample Entropy is significantly higher in elderly in sleep Stage 2 and REM, suggesting that in these two sleep stages the cortical state is closer to wake than in middle-aged women. Sample Entropy is higher in post-arousal compared to the pre-arousal and stays high for a 30 sec period.

The master´s thesis deals with fatigue evaluation in electrooculography records (EOG). The theoretical part focuses on electrooculography itself, fatigue and methods used for fatigue detection from EOG. The practical part includes a plan of optimal methodology for fatigue evaluation using EOG. The EOG signals are recorded during the volunteers are watching prepared scenes. Those scenes are desribed here. There is also definition of signal processing methods with relevant block diagrams. Laboratory protocol describing EOG signals recording using Biopac data acquisition system is included. Ten volunteers were measured according to this protocol and the signal database was created. In brief questionnaire volunteers were supposed to evaluate fatigue and discomfort of the measurment. Recorded signals were processed and acquired parameters were statistically evaluated. Then the parameters were discussed in terms of fatigue detection ability. On the basis of that software application was created. This application detects fatigue in selected signal. The thesis includes detailed laboratory manual for students.

The use of Electroencephalograms (EEG) are essential to the analysis of sleep disorders in patients. With the use of electroencephalograms, electro-oculograms (EOG), and electromyograms (EMG), doctors and EEG technician can make conclusions about the sleep patterns of patients. In particular, the classification of the sleep data into various stages, such as NREM I-IV, REM, Awake, is extremely important. The EEG signal itself is highly sensitive to physiological and non-physiological artifacts. Trained human experts can accommodate for these artifacts while they are analyzing the EEG signal. <br /><br /> However, if some of these artifacts are removed prior to analysis, their job will be become easier. Furthermore, one of the biggest motivations, of our team's research is the construction of a portable device that can analyze the sleep data as they are being collected. For this task, the sleep data must be analyzed completely automatically in order to make the classifications. <br /><br /> The research presented in this thesis concerns itself with the <em>denoising</em> and the <em>feature selection</em> aspects of the teams' goals. Since humans are able to process artifacts and ignore them prior to classification, an automated system should have the same capabilities or close to them. As such, the denoising step is performed to condition the data prior to any other stages of the sleep stage neoclassicisms. As mentioned before, the denoising step, by itself, is useful to human EEG technicians as well. <br /><br /> The denoising step in this research mainly looks at EOG artifacts and artifacts isolated to a single EEG channel, such as electrode pop artifacts. The first two algorithms uses Wavelets exclusively (BWDA and WDA), while the third algorithm is a mixture of Wavelets and In- dependent Component Analysis (IDA). With the BWDA algorithm, determining <em>consistent</em> thresholds proved to be a difficult task. With the WDA algorithm, the performance was better, since the selection of the thresholds was more straight-forward and since there was more control over defining the duration of the artifacts. The IDA algorithm performed inferior to the WDA algorithm. This could have been due to the small number of measurement channels or the automated sub-classifier used to select the <em>denoised EEG signal</em> from the set of ICA <em>demixed</em> signals. <br /><br /> The feature selection stage is extremely important as it selects the most pertinent features to make a particular classification. Without such a step, the classifier will have to process useless data, which might result in a poorer classification. Furthermore, unnecessary features will take up valuable computer cycles as well. In a portable device, due to battery consumption, wasting computer cycles is not an option. The research presented in this thesis shows the importance of a systematic feature selection step in EEG classification. The feature selection step produced excellent results with a maximum use of just 5 features. During automated classification, this is extremely important as the automated classifier will only have to calculate 5 features for each given epoch.

The use of Electroencephalograms (EEG) are essential to the analysis of sleep disorders in patients. With the use of electroencephalograms, electro-oculograms (EOG), and electromyograms (EMG), doctors and EEG technician can make conclusions about the sleep patterns of patients. In particular, the classification of the sleep data into various stages, such as NREM I-IV, REM, Awake, is extremely important. The EEG signal itself is highly sensitive to physiological and non-physiological artifacts. Trained human experts can accommodate for these artifacts while they are analyzing the EEG signal. <br /><br /> However, if some of these artifacts are removed prior to analysis, their job will be become easier. Furthermore, one of the biggest motivations, of our team's research is the construction of a portable device that can analyze the sleep data as they are being collected. For this task, the sleep data must be analyzed completely automatically in order to make the classifications. <br /><br /> The research presented in this thesis concerns itself with the <em>denoising</em> and the <em>feature selection</em> aspects of the teams' goals. Since humans are able to process artifacts and ignore them prior to classification, an automated system should have the same capabilities or close to them. As such, the denoising step is performed to condition the data prior to any other stages of the sleep stage neoclassicisms. As mentioned before, the denoising step, by itself, is useful to human EEG technicians as well. <br /><br /> The denoising step in this research mainly looks at EOG artifacts and artifacts isolated to a single EEG channel, such as electrode pop artifacts. The first two algorithms uses Wavelets exclusively (BWDA and WDA), while the third algorithm is a mixture of Wavelets and In- dependent Component Analysis (IDA). With the BWDA algorithm, determining <em>consistent</em> thresholds proved to be a difficult task. With the WDA algorithm, the performance was better, since the selection of the thresholds was more straight-forward and since there was more control over defining the duration of the artifacts. The IDA algorithm performed inferior to the WDA algorithm. This could have been due to the small number of measurement channels or the automated sub-classifier used to select the <em>denoised EEG signal</em> from the set of ICA <em>demixed</em> signals. <br /><br /> The feature selection stage is extremely important as it selects the most pertinent features to make a particular classification. Without such a step, the classifier will have to process useless data, which might result in a poorer classification. Furthermore, unnecessary features will take up valuable computer cycles as well. In a portable device, due to battery consumption, wasting computer cycles is not an option. The research presented in this thesis shows the importance of a systematic feature selection step in EEG classification. The feature selection step produced excellent results with a maximum use of just 5 features. During automated classification, this is extremely important as the automated classifier will only have to calculate 5 features for each given epoch.

The goal of this thesis is to investigate if it is possible to use measurements of physiological parameters to accelerate learning of target shooting for novice marksmen in Saab’s Ground combat indoor trainer (GC-IDT). This was done through a literature study that identified brain activity, eye movements, heart activity, muscle activity and breathing as related to shooting technique. The sensors types Electroencephalography (EEG), Electroocculography (EOG), Electrocardiogram (ECG), Electromyography (EMG) and impedance pneumography (IP) were found to be suitable for measuring the respective parameters in the GC-IDT. The literature study also showed that previous studies had found differences in the physiological parameters in the seconds leading up to the shot when comparing experts and novices. The studies further showed that it was possible to accelerate learning by giving feedback to the novices about their physiological parameters allowing them to mimic the behavior of the experts. An experiment was performed in the GC-IDT by measuring EOG, ECG, EMG and IP on expert and novice marksmen to investigate if similar results as seen in previous studies were to be found. The experiment showed correlation between eye movements and shooting score, which was in line with what previous studies had shown. The respiration measurement did not show any correlation to the shooting scores in this experiment, it was however possible to see a slight difference between expert and novices. The other measurements did not show any correlation to the shooting score in this experiment. In the future, further experiments needs to be made as not all parameters could be explored in depth in this experiment. Possible improvements to such experiments are i.e. increasing the number of participants and/or the number of shots as well as marking shots automatically in the data and increasing the time between shots.

Cílem této diplomové práce je najít a popsat souvislost mezi fixací očí v emočně zabarveném stimulu, kterým je obrázek či video, a EEG signálu. K tomuto studiu je třeba vyvinout softwarové nástroje v prostředí Matlab k úpravě a zpracování dat získaných z eye trackeru a propojení s EEG signály pomocí nově vytvořených markerů. Na základě získaných znalostí o fixacích, jsou v prostředí BrainVision Analyzeru EEG data zpracovány a následně jsou segmentovány a průměrovány jako evokované potenciály pro jednotlivé stimuly (ERP a EfRP). Tato práce je vypracována ve spolupráci s Gipsa-lab v rámci výzkumného projektu.

Driving sleepiness is a serious problem worldwide. It is of interest to develop reliable sleepiness detection systems to implement in vehicles, and for such a system both physi-ological data and driver performance data can be used. The reasons for driver sleepiness can be many, where an interesting factor to consider is the light condition of the environment, specifically daylight and darkness. Daylight and darkness has shown to affect human sleepiness in general and it is therefore of importance to investigate the effect of it on driver sleepiness independent of other factors. This thesis aimed to investigate whether light condition is a parameter that should be considered when developing a sleepiness detection system in a vehicle. This was done by investigating if the course of sleepiness would be affected by daylight and darkness, and if adding light condition information as a parameter to a classification model improved the performance of the sleepiness classification. To achieve this, the study was based upon data collected from driving simulator tests conducted by the Swedish National Road and Transport Research Institute (VTI). Test subjects drove in simulated daylight and darkness during both daytime while rested and nighttime while sleep-deprived. An exploratory and statistical analysis was conducted of several sleepiness indicators extracted from physio-logical data and simulator data. Three different classification models were implemented. The indicators pointed to a higher level of driver sleepiness during night compared to during day, as well as an increase with time on task. However, no clear trends pointed to daylight and darkness having affected the sleepiness of the driver. The classification models showed a marginal improvement when including light condition as a feature, however not large enough to draw any specific conclusion regarding the effect. The conclusion was that an effect of daylight and darkness on the course of driver sleepiness could not be seen in this thesis. The adding of light and dark as a feature did not significantly improve the classification models’ performances. In summary, further investigations of the effect of daylight and darkness in relation to driver sleepiness are needed.

The electro-oculogram (EOG) is the most widely used technique for recording eye movements in clinical settings. It is inexpensive, practical, and non-invasive. Use of EOG is usually restricted to horizontal recordings as vertical EOG contains eyelid artefact (Oster & Stern, 1980) and blinks. The ability to analyse two dimensional (2D) eye movements may provide additional diagnostic information on pathologies, and further insights into the nature of brain functioning. Simultaneous recording of both horizontal and vertical EOG also introduces other difficulties into calibration of the eye movements, such as different gains in the two signals, and misalignment of electrodes producing crosstalk. These transformations of the signals create problems in relating the two dimensional EOG to actual rotations of the eyes. The application of an artificial neural network (ANN) that could map 2D recordings into 2D eye positions would overcome this problem and improve the utility of EOG. To determine whether ANNs are capable of correctly calibrating the saccadic eye movement data from 2D EOG (i.e. performing the necessary inverse transformation), the ANNs were first tested on data generated from mathematical models of saccadic eye movements. Multi-layer perceptrons (MLPs) with non-linear activation functions and trained with back propagation proved to be capable of calibrating simulated EOG data to a mean accuracy of 0.33° of visual angle (SE = 0.01). Linear perceptrons (LPs) were only nearly half as accurate. For five subjects performing a saccadic eye movement task in the upper right quadrant of the visual field, the mean accuracy provided by the MLPs was 1.07° of visual angle (SE = 0.01) for EOG data, and 0.95° of visual angle (SE = 0.03) for infrared limbus reflection (IRIS®) data. MLPs enabled calibration of 2D saccadic EOG to an accuracy not significantly different to that obtained with the infrared limbus tracking data.