Submitted by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2018-03-08T14:54:09Z No. of bitstreams: 2 Dissertação_Naira S. G. Nogueira.pdf: 1893275 bytes, checksum: 2b8b41e0fb953880020eb1c0d34f0b4a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2018-03-08T14:54:23Z (GMT) No. of bitstreams: 2 Dissertação_Naira S. G. Nogueira.pdf: 1893275 bytes, checksum: 2b8b41e0fb953880020eb1c0d34f0b4a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) / Made available in DSpace on 2018-03-08T14:54:23Z (GMT). No. of bitstreams: 2 Dissertação_Naira S. G. Nogueira.pdf: 1893275 bytes, checksum: 2b8b41e0fb953880020eb1c0d34f0b4a (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-08-08 / Breast cancer is a aggressive diseasewhose, incidence and mortality hasves increased in recent years. For this reason it has raised concern about public health policies, being the target of research worldwide. Among the treatments for breast cancer is the radiation therapy, whichapplieuses ionizing radiation, however, with limitations due to is its toxic effects on normal tissues. The development of drugs of vegetal origin associated to the treatment of radiotherapy, has become very promising, since these substances modify the effects of the radiation minimizing its damages to the individual. The aim of the present study was to evaluate the in vitro effect of the propolis extract on the cell viability of MDA-MB-231 line adonocarcinoma cells and on the cell viability of human peripheral blood mononuclear cells (PBMC). The cells were irradiated with Low LET radiation (Linear Energy Transfer) according to the kinetics of predetermined doses (2 and 5 Gy) and supplemented with propolis extract at the concentrations of 0.5% and 1%, 5% and 10%. Post-irradiation collections were performed at the pre-established times of 24, 48 and 72 hours. The present study showed that ionizing radiation is accompanied by a significant decrease in cell viability parameters in peripheral blood mononuclear cells (PBMCs). While in the group of cells supplemented with propolis extract plus radiation, there was a decrease in the damage caused by these radiations. With regard to MDA-231 breast adenocarcinoma cells, there was a significant reduction in the survival level of these cells when subjected to radiation, whereas that effect was potentiated at the time the cell culture was supplemented With propolis extract. Supplementation with propolis extract in the treatment of radiotherapy offers a very measurable protection against cell damage to PBMCs. On the other hand, the propolis extract potentiates the cellular apoptosis of adenocarcinoma cells of resistant breast radio. The data obtained through this investigation can serve as a subsidy for the use of the propolis extract, potentializing the effects of radiotherapy treatment in patients with breast cancer. / O câncer de mama é uma doença agressiva cuja incidência e mortalidade tem aumentado nos últimos anos. Por esse motivo tem despertado preocupação por parte das políticas de saúde pública, sendo alvo de pesquisas internacionais e nacionais. Dentre os tratamentos para o câncer de mama tem-se a radioterapia, que se emprega radiação ionizante, no entanto com limitações devido a seus efeitos tóxicos nos tecidos normais. O desenvolvimento de drogas de origem vegetal associado ao tratamento de radioterapia é promissor, uma vez que estas substâncias modificam os efeitos da radiação minimizando seus danos ao paciente. O presente estudo teve como objetivo avaliar o efeito in vitro do extrato aquoso da própolis (EAP) sobre a viabilidade celular de células da linhagem de adenocarcinoma de mama MDA-MB-231 e sobre a viabilidade celular de células mononucleadas do sangue periférico humano (PBMC). As células foram irradiadas com radiação de baixa LET (Linear Energy Transfer) de acordo com a cinética de doses pré-determinadas (2 e 5 Gy) e suplementadas com EAP nas concentrações de 0,5% e 1%, 5% e 10%. As coletas pós-irradiação foram realizadas nos tempos pré-estabelecidos de 24, 48 e 72 horas. O presente estudo mostrou que as radiações ionizantes produzem efeito de diminuição significativa nos parâmetros de viabilidade celular em células mononucleares do sangue periférico (PBMCs). Enquanto que no grupo de células suplementadas com EAP em adição deradiação, os danos causados foram minimizados. No que diz respeito às células de adenocarcinoma de mama MDA-231, verificou-se que houve uma redução no nível de sobrevivência dessas células quando submetidas à radiação, ao passo que esse efeito foi potencializado no momento em que a cultura de células foi suplementada com extrato aquoso de própolis. A suplementação com extrato de própolis no tratamento de radioterapia ofereceu uma proteção bastante mensurável contra danos às células PBMCs. Além disso, o extrato de própolis potencializa a apoptose celular de células de adenocarcinoma de mama radio resistente. Os resultados através desta investigação podem servir como subsídio para a utilização do extrato de própolis potencializando os efeitos do tratamento radioterápico em pacientes com câncer de mama.

Network administrators typically employ di erent methods for authenticating and authorizing the access to their networks. A exible and scalable network access method is needed to combat the ever increasing network ubiquity brought on by technological advancements. The IEEE 802.1x Port-Based Network Access is a technology that allows transparent authentication to a network. It uses EAP-methods in order to authenticate against a server. There are a lot of di erent EAP-methods to choose from, and they vary in complexity and security. This report will bring up the di erences between the most commonly used authentication methods regarding the authentication time depending on di erent delay and network load. Results showed that EAP-methods that are less complex take less time to perform authentication than their counterparts. When there is no delay, or a very small delay, this might not matter, but when the delay is higher complex EAP-methods take signi cantly longer time to perform the authentication process. This is very negative considering the nature of transparent authentication, and could lead to users becoming annoyed. A general formula for determining how long time an EAP-authentication process will take is presented.

Den här rapporten beskriver en experimentell studie av Microsoft Network Protection (NAP) och är ämnad för att utvärdera hur mogen tekniken är för att implementeras i en aktiv nätverksmiljö. För att göra studien tog vi hjälp av gymnasieskolan John Bauer i Kalmar. Tester har utförts med DHCP-framtvingning och 802. 1x-framtvingning, dessa är två av NAPs fyra olika framtvingande funktioner. En mindre analys av skolans switchkonfigurationer och interna säkerhet har även gjorts på John Bauers begäran. Testerna har visat att DHCP-framtvingning är en bra och enkel lösning för John Bauers trådade klienter. NAP-funktionen 802. 1x- framtvingning var en större utmaning dock, och blev inte lyckad. Utbudet av information om NAP är än för knapphändig och vi anser därför att inte bara 802.1x framtvingning inte är redo för implementation, utan även framtvingning med DHCP.

L'utilisation des moyens de transport et des machines au quotidien a fortement contribué à l'amplification des phénomènes générant de la nuisance sonore. L'élimination des bruits en basses fréquences est actuellement la cible de différentes recherches. Plusieurs stratégies ont émergé comme l'utilisation des résonateurs de Helmholtz, de membranes vibrantes mais surtout des systèmes hybrides actif-passif. L'originalité de ce projet de doctorat consiste en la proposition d'une solution technologique d'un résonateur de Helmholtz adaptatif à volume variable, permettant ainsi de s'affranchir du caractère mono-fréquentiel des résonateurs de Helmholtz passifs. Le réglage de volume s'effectue grâce à l'utilisation d'une membrane en polymère électroactif (EAP), permettant ainsi d'accorder les résonances du système. Le comportement mécanique de ces matériaux est modifié lorsqu'ils sont stimulés par un champ électrique. Des améliorations significatives en perte par transmission acoustique sont obtenues en basses fréquences par deux effets: la variation de raideur de la membrane et l'augmentation de volume due à la déformation de la membrane. Des études numériques, analytiques et expérimentales sont réalisées pour déterminer le potentiel des concepts proposés. Enfin, une structure périodique contenant 9 résonateurs adaptatifs à membranes électroactives est étudiée en champs diffus permettant d'évaluer les performances acoustiques du concept distribué.

In any networking environment, security, connection time and scalability of the network are the major concerns to keep network safe, faster and stable. Administrators working within the networking environment need to have complete account of manageability, scalability and security of the network, so that the organizational data can be kept confidential and maintain integrity. There are different authentication methods used by network administrators for accessing network in wired and wireless environments. As network usage and attacks on network increases, a secure, scalable and standard network protocol is needed for accessing and to keep data safe in both wired and wireless networks. IEEE 802.1x is an IEEE standard used to provide authentication and authorization to the devices over LAN/WLAN. The framework IEEE 802.1x uses EAP for authentication and authorization with a RADIUS server. In this report, an experimental analysis for different EAP authentication methods in both wired and wireless networks in terms of authentication time and the total processing time is presented. Wireshark is used to capture the network traffic on server and client ends. After analyzing each packet timestamps that are captured using Wireshark, it is seen that EAP-MD5 takes less time in both wired and wireless networks, if the number of users increases, there is not much difference in the network connection time. Concerning with security of the network, EAP-MD5 is vulnerable to many attacks so it is not used by many companies. The alternative methods with their strengths and weaknesses are discussed.

Philosophiae Doctor - PhD / This study explores second and third year students' and teachers‟ views on factors that hinder or facilitate the mastery of English for Academic Purposes (EAP) in the Science and Engineering Technology Higher Institutions of learning in Rwanda (KIST) and seeks to establish the extent to which the current programme meets the needs of the students. This is done by highlighting a whole range of teacher and student perspectives on the EAP programme. Two key requirements invite students to write their academic assignments in the form of research proposals and research project reports. In order to help them perform well in their field subjects, KIST introduced a department of English with a General English Programme under the umbrella of the then School of Language Studies (SORAS) in 1997. The department‟s first assigned mission was to teach English to students in all departments in a bid to support and encourage them to cope with their field specific courses which are taught in English. Rwanda‟s National Council for Higher Education (2007), on language teaching and learning, states that the trio, that is Kinyarwanda (the Mother Tongue and national language) and English and French (as foreign languages), should be taught at primary, secondary and higher education levels in order to reconcile the divide between Rwandan returnees (who had lived abroad for many decades) and locals. It is in this context that KIST, one of the institutions of higher learning, adopted the bilingual policy to cater to students‟ needs to learn both French and English as media of academic communication. However, after Rwanda‟s integration into the East African Community and the Commonwealth, English has been officially adopted as the medium of instruction in all schools and higher institutions of education. That is why there was a sudden language shift in 2006 from French to English as a medium of instruction at KIST. French and Kinyarwanda are now merely taught as subjects. The motive behind the move was to cater for Rwanda‟s needs to fully participate in the economic community of East African Community in general and in the global economy in particular. The move drastically affected students‟ ability to read and write English in their respective disciplines. The move also affected lecturers of other speciality areas. To avert the obvious challenges emanating from this sudden shift in language policy, the Institute introduced the English for Specific Purposes (ESP) and English for Academic Purposes (EAP) programmes under the then KIST School of Language Studies (SOLAS) and the KIST Language Centre. However, appropriate instructional materials for such courses have not been easily available. Given this situation, English teachers have had to create their own materials rather than the existing generalised and pre-packaged language teaching materials. As a result, students‟ specific needs for induction into a scientific writing community at tertiary level have rarely been met. It is against this background that the study seeks to investigate factors that are facilitating and the mastery of EAP. The study operates on post-colonial/post-structuralist theoretical perspectives. These were founded on the analytical framework that is guided by thematic and/or conceptual underpinnings of language policy in the post-colonial Africa. Thus, English Language Teaching (ELT), developed into English as a second and additional language that is multi-semiotic and multi-modality in EAP and science genres, focusing mostly on its academic literacy, identity, ideology, power and agency, as well as its investment in language teaching and learning and the scientific community practice. Using a combination of ethnographic principles/practices like participants‟ observations, oneto- one interviews, focus group discussions and documentary review in data collection, the study utilises thematic/conceptual analysis to draw its conclusions. Drawing from the above conceptual perspectives, therefore, as well as from the methodological approach, this thesis emphasises the fact that the inability of students to successfully master EAP is caused by various factors, including the choice of English language learning materials. Contradictory approaches to language learning and to academic literacy practices create further challenges to the Rwandan students‟ advancement in English mastery. These same practices also serve to limit the students‟ ability to learn this language and complicate their access to local and global cultural exposure that is necessary for their socio-economic development of Rwanda. The study also reveals lack of appropriate discursive competence and multi-semiotic repertoires as some of the major factors inhibiting students‟ academic progress. This is partly explained by the nature of the English language learning and teaching materials that is in use which neither provides general nor disciplinary specific academic and learning opportunities in English. Similarly, a range of structural and professional constraints on „agency‟ exists for teachers of English in Rwanda as an additional language to the students, including lack of induction into scientific discourses or the EAP community of language practice. The overall lack of power and agency by teachers also contributes to constraints and constrictions in English language learning practices for these students in Rwanda. The study, however, observes that this situation is not only peculiar to KIST, as it is also common in almost all tertiary institutions in Rwanda. Specific recommendations are made in the study to improve the quality of English language learning and teaching in general and EAP in particular at KIST as an institution of higher learning, through the establishment of a clearer language policy and training opportunities for staff to update and develop required language skills in EAP, especially with regards to writing skills in sciences and engineering. The government of Rwanda, under the umbrella of Rwanda Education Board (REB) and the contribution of English language experts at the Institute, should provide a clearer direction of the language policy and curriculum that addresses Rwandan students‟ specific needs. KIST, as an institution of higher learning, should value and facilitate the teaching and learning of English in general and the teaching of EAP in particular, bearing in mind its assigned mission. The management of the Institute should encourage interaction between EAP and subject area lecturers to discuss and agree upon, text types to be used by EAP lecturers in teaching. KIST management should also provide room for regular interactions with English lecturers to listen to their views and offer them further language training opportunities in order to update and develop the required skills in EAP, especially with regards to writing skills in science and engineering. / South Africa

Philosophiae Doctor - PhD / This study explores second and third year students' and teachers‟ views on factors that hinder or facilitate the mastery of English for Academic Purposes (EAP) in the Science and Engineering Technology Higher Institutions of learning in Rwanda (KIST) and seeks to establish the extent to which the current programme meets the needs of the students. This is done by highlighting a whole range of teacher and student perspectives on the EAP programme. Two key requirements invite students to write their academic assignments in the form of research proposals and research project reports. In order to help them perform well in their field subjects, KIST introduced a department of English with a General English Programme under the umbrella of the then School of Language Studies (SORAS) in 1997. The department‟s first assigned mission was to teach English to students in all departments in a bid to support and encourage them to cope with their field specific courses which are taught in English. Rwanda‟s National Council for Higher Education (2007), on language teaching and learning, states that the trio, that is Kinyarwanda (the Mother Tongue and national language) and English and French (as foreign languages), should be taught at primary, secondary and higher iv education levels in order to reconcile the divide between Rwandan returnees (who had lived abroad for many decades) and locals. It is in this context that KIST, one of the institutions of higher learning, adopted the bilingual policy to cater to students‟ needs to learn both French and English as media of academic communication. However, after Rwanda‟s integration into the East African Community and the Commonwealth, English has been officially adopted as the medium of instruction in all schools and higher institutions of education. That is why there was a sudden language shift in 2006 from French to English as a medium of instruction at KIST. French and Kinyarwanda are now merely taught as subjects. The motive behind the move was to cater for Rwanda‟s needs to fully participate in the economic community of East African Community in general and in the global economy in particular. The move drastically affected students‟ ability to read and write English in their respective disciplines. The move also affected lecturers of other speciality areas. To avert the obvious challenges emanating from this sudden shift in language policy, the Institute introduced the English for Specific Purposes (ESP) and English for Academic Purposes (EAP) programmes under the then KIST School of Language Studies (SOLAS) and the KIST Language Centre. However, appropriate instructional materials for such courses have not been easily available. Given this situation, English teachers have had to create their own materials rather than the existing generalised and pre-packaged language teaching materials. As a result, students‟ specific needs for induction into a scientific writing community at tertiary level have rarely been met. It is against this background that the study seeks to investigate factors that are facilitating and the mastery of EAP. The study operates on post-colonial/post-structuralist theoretical perspectives. These were founded on the analytical framework that is guided by thematic and/or conceptual underpinnings of language policy in the post-colonial Africa. Thus, English Language Teaching (ELT), developed into v English as a second and additional language that is multi-semiotic and multi-modality in EAP and science genres, focusing mostly on its academic literacy, identity, ideology, power and agency, as well as its investment in language teaching and learning and the scientific community practice.

Philosophiae Doctor - PhD / Findings also indicate other drawbacks such as some teachers' transmission of errors due to their low proficiency in the English language, their lack of common and well-designed EAP curricula, their lack of cooperation with non-language teachers, their delayed starting of classes and allowing a kind of laissez-faire and laissez-aller approach in classrooms, their lack of promotion of students' learning autonomy and problem-solving skills, their lack of language support to students, to cite but a few. Findings also indicate that teachers over-used pre-established materials that they had been recommended to use, using a teaching methodology known as PPP (Present Practise Produce) according to which teachers present an item or a skill and students are required to practise it before they become conversant with it. Furthermore, findings indicate a severe shortage of teaching and learning facilities. Findings concerning the language of instruction (English) indicate that it challenged students with an educational background in French. However, the students' French background and the widespread use of Kinyarwanda were also seen as an impediment to the implementation of EAP courses, but findings show that the shift from English to Kinyarwanda would help students understand the difficult concepts used in their academic subjects and safeguard Rwandan culture. Findings with regard to students' needs and expectations indicate that no opportunities were created for classroom interaction to enable students to think critically and comprehend the world and the word. Furthermore, teachers would fail to adjust the teaching and learning materials to suit students' needs. These materials were neither discipline-nor culture-related. To address the above-mentioned shortcomings, findings indicate that teaching and learning materials which incorporate discipline-related terminologies, Rwandan cultural artifacts, and world Englishes bear meaningful input and can raise students' motivation. They also indicate that students communicate better in Kinyarwanda and that the use of code switching helps students acquire both Basic Interpersonal Communication Skills (BICS) and Cognitive Academic Language proficiency (CALP). Concerning the above findings, therefore, recommendations are made to help the CBE and other institutions of higher learning in Rwanda and tertiary education settings in non-native English-speaking countries around the world to use EAP courses as a solution to students' language- related problems. Such recommendations are, to cite a few, teachers' shift from a banking to a problem-solving model of education, their switch to modes of communication other than the language of instruction to facilitate the teaching and learning process, teacher and student autonomy, accommodating students' voice in the teaching and learning process, the revision of criteria relied on to select language teachers, and in-service training for novice teachers. Other recommendations are CBE's partnership with other institutions of higher learning nationwide and worldwide, provision of learning and teaching materials, the government's mass consultation before the promulgation and implementation of any language policy, and the consideration of student errors as part of the learning process.

The researcher has since 1996 been involved professionally in the field of Employee Assistance and has been witness to its evolution, growing complexity and potential to make a positive impact on the development of individuals and organizations through employer-employee relationship and workplace dynamics. The motivation for this study came from an interest to gain deeper understanding of the concept and implementation of EAPs by organizations in the researcher’s immediate environment and circle of potential influence. The development of EAPs in South Africa, influenced by various professions, has evolved as a result of different organizational needs which occur in varying forms and levels of sophistication depending on staffing, availability of resources and capacity within organizations. There is limited information available to EAP as a developing profession in terms of how programmes occur in South Africa. This study sought to analyze the prevalence and nature of EAPs in work organizations within the Buffalo City Municipal Area (BCMA) in the Eastern Cape Province, mainly to obtain reliable information on these programmes so that implementation of employee assistance can be evaluated and improved. This investigation provides a critical description of the implementation of EAPs in the BCMA with a view to establish prevalence, critically analyze the nature of EAPs, and to benchmark against existing Employee Assistance Professional Standards. The literature review includes a detailed examination of the history of EAPs in South Africa, contributions of the different professional disciplines, definitions of EAP, models currently in practice with the advantages, disadvantages and factors that influence the organizations choice of model and core technology of EAPs, as well as a critical examination of the 27 EAPA-SA Standards of 2005. The study is quantitative, exploratory and descriptive in nature as it sought to measure prevalence and provide descriptions of implementation methodologies in terms of form, shape, scope, staffing and services offered. These descriptive elements are benchmarked against the Standards for EAPs in South Africa, developed by the EAPA-SA, the official voice of the EAP profession. Questionnaires were administered to respondents that attended the local EAPA Branch and Occupational Health Nurses Association as well as Provincial Forum for Public Sector EAPs meetings. The respondents that were not reached this way were administered questionnaires personally. The population included organizations from both the private and public sector that employed a minimum staff compliment of two hundred. Since there are only 47 such organizations in the BCMA (both public and private sector), the entire population consisted of respondents and no sample was selected. Univariate analysis was used to assess data collected. The findings of the study indicate that EAPs are prevalent in BCMA organizations but they vary considerably in the way they have been developed and implemented. Benchmarked against the EAPA-SA Standards it is evident that while employee assistance programmes have certain basic elements in common, the overall design and implementation is fortuitous at best. Since the EAPA-SA standards have been developed concurrently with EAPs it is hoped that newly established EAPs will be a product of careful design rather than an inadvertent incident. EAPA-SA, educational institutions and business development forums need to collaborate and partner to provide comprehensive support to organizations and EAP practitioners to strengthen their EAPs. Correctly implemented, capacitated and resourced, EAPs can assist organizations to effectively manage their human resource behavior and health risks, maximize productivity as well as support individual employees to optimally manage personal and work challenges and function at their best. Copyright / Dissertation (MSW)--University of Pretoria, 2010. / Social Work and Criminology / unrestricted

The main impetus for conducting research of this type was for the researcher to better understand the nature and types of EAP and HIV and Aids programmes that exist in the selected Gauteng Public Service departments. The researcher was motivated to choose this subject as she was employed by the Gauteng Department of Education and is currently employed by the Gauteng Department of Health of which these departments are the largest departments in the province and was able see both the similarities and differences between how the EAP and HIV and Aids Workplace programmes were being conducted. One similarity between the programmes is that both EAP and HIV and Aids Workplace Programmes are concerned with employee well-being with the aim of enhancement of the quality of work life and productivity. Employee assistance programmes commenced in Gauteng as a directive from the office of the Premier in 1999 (Gauteng Department of Education [GDE] Draft EAP Policy, 2003).This directive was the seed that led the development of both EAP and HIV and Aids Workplace Programmes in the Gauteng Province. This was a smart decision of investing its employee’s wellness and was strategically originating from the top structure within the province. In this research an exploratory study was undertaken in order to identify the relationship between EAP and HIV and Aids Workplace Programmes in nine Gauteng government departments. The survey design was used within the quantitative approach and use was made of a structured questionnaire. The study was made up of the responses elicited from 14 employees representing 9 state departments within the Gauteng Provincial Government. These respondents were directly responsible for both or either EAP and HIV and Aids Workplace Programmes. Applied research, considers a situation in practice to answer practical question about the EAP and HIV and Aids Workplace Programmes within GPG, was used. The researcher sent out sixteen questionnaires using a purposive sampling method to select respondents for this study. A discussion of the theoretical overview covered EAP and HIV and Aids Workplace Programmes in South Africa. This was further delineated to EAP and HIV and Aids Workplace programmes in the public sector and to the Gauteng Province. The research findings indicated that that the departments surveyed varied drastically in terms of employee size from 60000 to 292. The majority of the respondents were female and were EAP coordinators and the most frequent undertaken daily task was counselling, although many of the government departments had been making use of an external service provider to render an EAP service. Counselling was a service offered by the external service provider. Other findings were that the majority of the respondent’s had a university degree and many even had post-graduate qualifications. Almost all departments surveyed had policies that were relevant to EAP and HIV and Aids Workplace Programmes in place. The recommended requirements needed to sustain the EAP and HIV and Aids Workplace programmes include the following: • Locating the EAP and HIV and Aids Workplace programmes at top management level within the respective departments. • Combining the HIV and Aids Workplace Programmes and EAP under the banner of Employee Wellness. • Ensuring that these programmes are adequately resourced both in terms of budget and staff. • On-going marketing of the programmes to increase utilization. This research has highlighted the need for an integrated programme under the banner of wellness that can holistically serve the needs of employees. EAP and HIV and Aids Workplace Programmes practised in isolation are not as effective as a integrated customised programme designed to suit the individual requirements of an organization and its employees. / Dissertation (MSD (Employee Assistance Programme))--University of Pretoria, 2008. / Social Work and Criminology / unrestricted