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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Diagn?stico da cardiomiopatia hipertr?fica em gatos (Felis catus Linnaeus,1758) pelo curto dom?stico / Diagnosis of hypertrophic cardiomyopathy in cats (Felis catus Linnaeus, 1758) by domestic short

Silva, Bruno Ricardo Soares Alberigi da 29 February 2016 (has links)
Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2017-03-24T11:59:07Z No. of bitstreams: 1 2016 - Bruno Ricardo Soares A. da Silva.pdf: 2937766 bytes, checksum: 9d74f19c8b592d9a097f535ef56dd464 (MD5) / Made available in DSpace on 2017-03-24T11:59:07Z (GMT). No. of bitstreams: 1 2016 - Bruno Ricardo Soares A. da Silva.pdf: 2937766 bytes, checksum: 9d74f19c8b592d9a097f535ef56dd464 (MD5) Previous issue date: 2016-02-29 / Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES / Hypertrophic cardiomyopathy is the most common heart disease in cats and it is characterized by concentric left ventricular hypertrophy. It is a genetic disease, autosomal dominant with incomplete penetrance, which predispose animals to minor changes in the cardiovascular system as arrhythmias and thromboembolism, these being possible causes of sudden death of these animals. Although traditionally linked to the involvement of breeds of cats like Maine Coon, Ragdoll, Sphynx and Persian, hypertrophic cardiomyopathy can affect any breed and even mixed breed cats. The aim of this study was the diagnosis of hypertrophic cardiomyopathy in a population of domestic short hair cats, and relate with the clinical and imaging findings with early diagnosis. Were evaluated 135 domestic short hair cats by Doppler echocardiography, between males and females of different ages, no previous history of suspected heart disease, to identify the concentric ventricular hypertrophy of the left ventricle. Were recognized cats with hypertrophy those, which interventricular septum and the free wall of the left ventricle measures during diastole, animal that presented 5 mm thickness on this measures. Animals identified with concentric ventricular hypertrophy were subjected to laboratory tests of urea, creatinine, sodium, potassium, ionized calcium, phosphorus, T4total, urinalysis, and imaging tests like ultrasound for differential diagnosis of diseases that can cause concentric hypertrophy, such as hypertension, chronic kidney disease, hyperaldosteronism and hyperthyroidism. Were diagnosed 10 cats with concentric ventricular hypertrophy, these five were classified as having concentric secondary ventricular hypertrophy to other diseases and five characterized as having hypertrophic cardiomyopathy. Among the results was noted that hypertrophic cardiomyopathy presents: 1) prevalence of 3.7%; 2) silent evolution for clinical aspects; 3) even with borderline measures, has changes that need monitoring for early diagnosis of complications; 4) a phenotypic diversity as the site of involvement / A cardiomiopatia hipertr?fica, ? a cardiopatia mais comum nos gatos, sendo caracterizada pela hipertrofia conc?ntrica do ventr?culo esquerdo. ? uma doen?a de origem gen?tica, autoss?mica dominante de penetr?ncia incompleta, que predisp?em os animais a altera??es secund?rias do sistema cardiovascular como arritmias e tromboembolismo, causas poss?veis de morte s?bita destes animais. Apesar de sua ocorr?ncia estar tradicionalmente relacionada ?s ra?as Maine Coon, Ragdoll, Sphynx e Persa, a cardiomiopatia hipertr?fica pode acometer qualquer outra ra?a e at? mesmo gatos sem ra?a definida. O objetivo do presente estudo foi realizar o diagn?stico da cardiomiopatia hipertr?fica em uma popula??o de gatos pelo curto dom?stico, e relacionar os achados cl?nicos e de imagem com diagn?stico precoce da doen?a. Foram submetidos ao exame ecodopplercardiogr?fico 135 gatos pelo curto dom?stico, entre machos e f?meas de diferentes idades, sem hist?rico pr?vio de suspeita de cardiopatia, para identifica??o da hipertrofia ventricular conc?ntrica do ventr?culo esquerdo. Foram considerados animais portadores de hipertrofia aqueles que apresentaram medidas de septo interventricular e/ou parede livre do ventr?culo esquerdo, ambos na di?stole, maiores que 5 mm de espessura. Os animais identificados com hipertrofia ventricular conc?ntrica, foram submetidos, al?m do exame cl?nico, ? exames laboratoriais de ureia, creatinina, s?dio, pot?ssio, c?lcio i?nico, f?sforo, T4total e urin?lise, e exames de imagem como ultrassonografia, para diagn?stico diferencial de doen?as que possam causar hipertrofia conc?ntrica, como hipertens?o arterial, doen?a renal cr?nica, hiperaldosteronismo e hipertireoidismo. Foram diagnosticados 10 gatos portadores de hipertrofia ventricular conc?ntrica, destes cinco foram classificados como portadores de hipertrofia ventricular conc?ntrica secund?ria a outras doen?as, sendo o hipertireoidismo a principal causa (4/5) e cinco caracterizados como portadores de cardiomiopatia hipertr?fica. Com base nos resultados p?de-se concluir que a cardiomiopatia hipertr?fica: 1) apresentou preval?ncia de 3,7% na popula??o de gatos pelo curto dom?stico da cidade do Rio de Janeiro; 2) cursa com evolu??o silenciosa quanto aos aspectos cl?nicos; 3) apresentou diversidade fenot?pica quanto ao local de acometimento no ventr?culo esquerdo; e 4) al?m da espessura de septo e parede livre na di?stole, outras medidas ecodopplercardiogr?ficas lim?trofes sinalizam a necessidade de acompanhamento do paciente, para diagn?stico precoce de futuras complica??es

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