The biological effects of charged particles is of interest in particle therapy, radiation protection and space radiation science and known to be dependent on both absorbed dose and radiation quality or LET. Microdosimetry is a technique which uses a tissue equivalent gas to simulate microscopic tissue sites of the order of cellular dimensions and the principles of gas ionization devices to measure deposited energy. The Gas Electron Multiplier (GEM) has been used since 1997 for tracking particles and for the determination of particle energy. In general, the GEM detector works in either tracking or energy deposition mode. The instrument proposed here is a combination of both, for the purpose of determining the energy deposition in simulated microscopic sites over the charged particle range and in particular at the end of the range where local energy deposition increases in the so‐called Bragg‐peak region. The detector is designed to track particles of various energies for 5 cm in one dimension, while providing the particle energy deposition every 0.5 cm of its track. The reconfiguration of the detector for different particle energies is very simple and achieved by adjusting the pressure of the gas inside the detector and resistor chain. In this manner, the detector can be used to study various ion beams and their dose distributions to tissues. Initial work is being carried out using an isotopic source of alpha particles and this thesis will describe the construction of the GEM‐based detector, computer modelling of the expected gas‐gain and performance of the device as well as comparisons with experimentally measured data of segmented energy deposition. / UOIT

<p> In experimental microdosimetry one of the goals is to measure the absorbed dose in microscopic volumes of tissue. The traditional spherical tissue-equivalent proportional counter (TEPC) is the most common detector currently used for microdosimetry. A new microdosimetric detector based on a thick gas electron multiplier (THGEM) was developed. To investigate the feasibility of the THGEM type detector for microdosimetry, a prototype detector was designed and manufactured. The THGEM detector is robust, easy to manufacture and is cost effective. The THGEM foil is composed of a thin FR4-epoxy insulator coated with copper on both sides. The THGEM contains 32 holes each with a diameter of 0.35 mm and pitch of 0.64 mm. The sensitive volume of the detector is a right cylinder with a diameter of ~5 mm and height of ~5 mm and is located in the center of the detector. Systematic tests were conducted at the McMaster Accelerator Laboratory to investigate its overall performance. A neutron-gamma ray radiation field was generated using the 7Li(p,n) reaction. The detector was operated at low bias voltages initially to test the stability and then the relative multiplication gain was measured as a function of the operating high voltage. The detector performance was observed with different THGEM insulator thicknesses ranging from 0.12 mm to 1.48 mm. The multiplication gain was assessed and both neutron and gamma-ray radiation was detected by the THGEM detector. The spectra obtained with the THGEM detector were analyzed and compared to the data collected with the standard spherical TEPC. The investigations provided information about the THGEM detector operation for microdosimetry and the THGEM microdosimetric spectra observed are comparable to the standard TEPC data.</p> / Thesis / Doctor of Philosophy (PhD)

A new beta-ray detector using the Thick Gas Electron Multiplier (THGEM) technology is presented. Traditional proportional counters have been considered the standard for many decades for radiation contamination monitoring. However, it has always been challenging to detect low energy beta-emitters such as 3H and 14C. In order to extend the low energy cut-off of these beta particles, it is important to keep the electron multiplication gain as high as possible. To accomplish this goal, we have developed a new gaseous beta-ray detector using THGEMs. Founded on previous THGEM avalanche simulations [1] and predecessor detectors, a novel prototype THGEM beta-ray detector was designed and fabricated. Its signal performance, effective gain and gain stability were comprehensively studied for single and double-THGEM configurations using an alpha source. The first time THGEM detector response to beta-rays was observed for various operating conditions and compared with Monte Carlo N-Particle Transport 6 (MCNP6) Monte Carlo simulations. / Thesis / Master of Science (MSc)

Radiations can be classified as either ionizing or non-ionizing according to whether it ionizes or does not ionize the medium through which they propagate. X-rays photons and gamma rays are the typical examples of ionizing radiations whereas radiowave, heat or visible light are examples of non ionizing radiations. UV photons have some features of both ionizing and non-ionizing radiation. Both ionizing and non-ionizing radiation can be harmful to living organisms and to the natural environment. Hence the detection and measurement of radiation is very important for the well being of living organisms as well as the natural environment. Not only for safety reasons, have radiation detectors found their applications in various fields including medical physics, nuclear and particle physics, astronomy and homeland security. Industrial sectors that use radiation detection include medical imaging, security and baggage scanning, the nuclear power industry and defense. Gas electron multiplier (GEM) is one of the most successful representatives of gaseous detectors used for UV photon and X-ray photon detection. Recently there is a growing demand for large area photon detectors with sensitivity reaching to the level of single photon. They are used in spectroscopy and imaging in astronomy high energy physics experiments etc. Thick GEM (THGEM) is a mechanical expansion of standard GEM. It has all the necessary requirements needed for large area detector and offers a multiplication factor that permits efficient detection of light. Hence, the development and performance study of THGEM based radiation detector is chosen as the topic of study in the present thesis. The initial part of the thesis contains simulation studies carried out for the understanding the working of the detector and the effect of various design parameters of THGEM for the above said applications. Different steps for the fabrication of THGEM and the technical challenges faced during the process are discussed. In the view of application of the fabricated THGEM for UV photon detection, cesium iodide photocathode is prepared using thin film technology and characterized. The performance of the photocathode under various operating conditions is studied in terms of its photoemission property. The effect of vacuum treatment on the photoemission property of the photocathode exposed to moist air is studied in detail. A major portion of this thesis focuses on maximizing the detection efficiency of the UV photon detector realized using the fabricated THGEM coupled with the cesium iodide photocathode. Simulations are used at different stages to interpret the experimental observations. The electron spectrum obtained from the detector under study was analyzed. The dependence of secondary effect like photon feedback on the operating parameters is also discussed. The last portion of the thesis deals with the application of THGEM as an X-ray detector. The performance is evaluated in terms of the gain and energy resolution achieved. The thesis is organized as follows: Chapter 1 is divided into two sections. Section A gives a general introduction to different types of radiation detectors found in the present day and their working principles. This is followed by discussion about gas ionization based detector and its working principle in detail. A brief literature survey of the different types of micropattern gas detectors is also given in this section. In Section B of this chapter GEM and THGEM are introduced with discussion about their working principle and areas of application. Chapter 2 deals with the simulation study of THGEM undertaken to have a clear understanding of the detector’s working. Section A of this chapter gives an overview of the simulation tools used for the present thesis in particular ANSYS and GARFIELD. Section B presents the results of the simulation study highlighting the effects of different geometrical and operating parameters on the electric field distribution in and around the THGEM aperture. The relevance of the study to the detectors performance is discussed vividly for all the cases. In Chapter 3, the details of the different steps involved in THGEM fabrication are given. Design aspects involved, fabrication of the THGEM using standard PCB technology coupled with photolithography technique are discussed in this chapter. This is followed by an elaborate description of the test setup used for all the performance study. Preface In the view of application of THGEM as a UV photon detector, cesium iodide photocathode was prepared and characterized. Chapter 4 discusses about the CsI photocathode preparation and its characterization for the above said application. Photoemission property of the photocathode was analyzed under various operating parameters. The effect of vacuum treatment on the photocathode performance is a new aspect of this thesis. Its correlation with the microstructure of the film is reported for the first time. Chapter 5 deals with the application of THGEM as a UV photon detector. The study mainly focuses on the improvement of the detection efficiency of the detector. The effect of drift parameters on the electron transfer efficiency and hence on the detection efficiency of the detector is a major contribution of this thesis. There are no literature available which discusses this aspect of a UV photon detector. The experimental study has been supported with simulation results. In addition to the study on detection efficiency, electron spectrum has also been acquired from the UV photon detector. The spectrum has been analyzed under various operating conditions. Discussions about secondary effects like photon feedback prevailing in the detector output are also present in this chapter. Chapter 6 presents the results of THGEM as an X-ray detector. The performance of the detector has been evaluated in terms of the effective gain and energy resolution achieved under different operating conditions. The gain instability with time and its uniformity across the THGEM area are also studied. The effect of drift field on the energy resolution and its correlation with ETE is a new aspect of this work. Chapter 7 summarizes the salient features of the work presented in this thesis. Also the scope of future work based on this thesis is discussed at the end of the chapter.

<p>Currently film is being replaced by electronic detectors for portal imaging in radiation therapy. This development offers obvious advantages such as on-line quality assurance and digital images that can easily be accessed, processed and communicated. In spite of the improvements, the image quality has not been significantly enhanced, partly since the quantum efficiency compared to film is essentially the same, and the new electronic devices also suffer from sensitivity to the harsh radiation environment. In this thesis we propose a third generation electronic portal imaging device with increased quantum efficiency and potentially higher image quality.</p><p>Due to the parallel readout capability it is much faster than current devices, providing at least 200 frames per second (fps), and would even allow for a quality assurance and adaptive actions after each accelerator pulse. The new detector is also sensitive over a broader range of energies (10 keV - 50 MeV) and can be used to obtain diagnostic images immediately prior to the treatment without repositioning the patient. The imaging could be in the form of portal imaging or computed tomography. The new detector is based on a sandwich design containing several layers of Gas Electron Multipliers (GEMs) in combination with, or integrated with, perforated converter plates. The charge created by the ionizing radiation is drifted to the bottom of the assembly where a tailored readout system collects and digitizes the charge. The new readout system is further designed in such a way that no sensitive electronics is placed in the radiation beam and the detector is expected to be radiation resistant since it consists mainly of kapton, copper and gas.</p><p>A single GEM detector was responding linearly when tested with a 50 MV photon beam at a fluence rate of ~10¹⁰ photons mm^-2 s^-1 during 3-5 μs long pulses, but also with x-ray energies of 10-50 keV at a fluence rate of up to ~10⁸ photons mm^-2 s^-1. The electron transmission of a 100 μm thick Cu plate with an optical transparency of ~46% was found to be ~15.4%, i.e. the effective hole transmission for the electrons was about one third of the hole area. A low effective GEM gain is enough to compensate for the losses in converters of this dimension. A prototype for the dedicated electronic readout system was designed with 50 x 100 pixels at a pitch of 1.27 mm x 1.27 mm. X-ray images were achieved with a single GEM layer and also in a double GEM setup with a converter plate interleaved. To verify the readout speed a Newton pendulum was imaged at a frame rate of 70 fps and alpha particles were imaged in 188 fps. The experimental studies indicates that the existing prototype can be developed as a competitive alternative for imaging in radiation therapy.</p>

<p>The work describes the development of a reliable device for profiling anion beam in the intensity cross section. A sensor head consisting of a Faradaycup in combination with a Channel Electron Multiplier was designedand built together with electronics including power supply and front endelectronics. The design was chosen considering financial and long term lifeaspects. Testing, first calibration and error analysis were done using the ionbeam facilities where the unit is supposed to be installed permanently. Theprofiling system performed as designed and the profile of the ion beam couldbe measured reliably with an accuracy down to the femto ampere range.</p>

Currently film is being replaced by electronic detectors for portal imaging in radiation therapy. This development offers obvious advantages such as on-line quality assurance and digital images that can easily be accessed, processed and communicated. In spite of the improvements, the image quality has not been significantly enhanced, partly since the quantum efficiency compared to film is essentially the same, and the new electronic devices also suffer from sensitivity to the harsh radiation environment. In this thesis we propose a third generation electronic portal imaging device with increased quantum efficiency and potentially higher image quality. Due to the parallel readout capability it is much faster than current devices, providing at least 200 frames per second (fps), and would even allow for a quality assurance and adaptive actions after each accelerator pulse. The new detector is also sensitive over a broader range of energies (10 keV - 50 MeV) and can be used to obtain diagnostic images immediately prior to the treatment without repositioning the patient. The imaging could be in the form of portal imaging or computed tomography. The new detector is based on a sandwich design containing several layers of Gas Electron Multipliers (GEMs) in combination with, or integrated with, perforated converter plates. The charge created by the ionizing radiation is drifted to the bottom of the assembly where a tailored readout system collects and digitizes the charge. The new readout system is further designed in such a way that no sensitive electronics is placed in the radiation beam and the detector is expected to be radiation resistant since it consists mainly of kapton, copper and gas. A single GEM detector was responding linearly when tested with a 50 MV photon beam at a fluence rate of ~1010 photons mm-2 s-1 during 3-5 μs long pulses, but also with x-ray energies of 10-50 keV at a fluence rate of up to ~108 photons mm-2 s-1. The electron transmission of a 100 μm thick Cu plate with an optical transparency of ~46% was found to be ~15.4%, i.e. the effective hole transmission for the electrons was about one third of the hole area. A low effective GEM gain is enough to compensate for the losses in converters of this dimension. A prototype for the dedicated electronic readout system was designed with 50 x 100 pixels at a pitch of 1.27 mm x 1.27 mm. X-ray images were achieved with a single GEM layer and also in a double GEM setup with a converter plate interleaved. To verify the readout speed a Newton pendulum was imaged at a frame rate of 70 fps and alpha particles were imaged in 188 fps. The experimental studies indicates that the existing prototype can be developed as a competitive alternative for imaging in radiation therapy.

The work describes the development of a reliable device for profiling anion beam in the intensity cross section. A sensor head consisting of a Faradaycup in combination with a Channel Electron Multiplier was designedand built together with electronics including power supply and front endelectronics. The design was chosen considering financial and long term lifeaspects. Testing, first calibration and error analysis were done using the ionbeam facilities where the unit is supposed to be installed permanently. Theprofiling system performed as designed and the profile of the ion beam couldbe measured reliably with an accuracy down to the femto ampere range.

The aim of this research was to demonstrate a high current and stable field emission (FE) source based on carbon nanotubes (CNTs) and electron multiplier microchannel plate (MCP) and design efficient field emitters. In recent years various CNT based FE devices have been demonstrated including field emission displays, x-ray source and many more. However to use CNTs as source in high powered microwave (HPM) devices higher and stable current in the range of few milli-amperes to amperes is required. To achieve such high current we developed a novel technique of introducing a MCP between CNT cathode and anode. MCP is an array of electron multipliers; it operates by avalanche multiplication of secondary electrons, which are generated when electrons strike channel walls of MCP. FE current from CNTs is enhanced due to avalanche multiplication of secondary electrons and in addition MCP also protects CNTs from irreversible damage during vacuum arcing. Conventional MCP is not suitable for this purpose due to the lower secondary emission properties of their materials. To achieve higher and stable currents we have designed and fabricated a unique ceramic MCP consisting of high SEY materials. The MCP was fabricated utilizing optimum design parameters, which include channel dimensions and material properties obtained from charged particle optics (CPO) simulation. Child Langmuir law, which gives the optimum current density from an electron source, was taken into account during the system design and experiments. Each MCP channel consisted of MgO coated CNTs which was chosen from various material systems due to its very high SEY. With MCP inserted between CNT cathode and anode stable and higher emission current was achieved. It was ~25 times higher than without MCP. A brighter emission image was also evidenced due to enhanced emission current. The obtained results are a significant technological advance and this research holds promise for electron source in new generation lightweight, efficient and compact microwave devices for telecommunications in satellites or space applications. As part of this work novel emitters consisting of multistage geometry with improved FE properties were was also developed.

In preparation for the High-Luminosity Large Hadron Collider (HL-LHC) at CERN, the Compact Muon Solenoid (CMS) Detector is undergoing a series of upgrades to its existing infrastructure, and is adding in several completely new subdetector systems. The first of these new systems, called GE1/1, is a series of 144 gas electron multiplier (GEM) detectors, arranged as 36 two-detector "superchambers" in each of the muon endcaps of CMS. These detectors are a subtype of micropattern gas detectors, and consist of three layers of "GEM foils", thin sheets of polyimide coated with 5 um of copper on each side and chemically etched with holes of 50 - 70 um diameter at a pitch of 140 um. These layers are stacked on top of a printed circuit board (PCB) readout and sealed within a gastight volume that is filled with Ar:CO2 70:30, and a high voltage is applied to the foils to create electric fields within the GEM detectors. When a muon enters the detector and ionizes the gas within, the ionized electrons encounter these fields and multiply in Townsend avalanches at each successive foil layer, until they are read out at the readout PCB at a gain of ~10^4. In early 2017, a demonstrator system known as the "slice test" was installed into the negative endcap. Consisting of 10 GEM detectors, the two-year-long slice test served as both a proof of concept for the GE1/1 system and an invaluable learning experience that would permanently impact not only the GE1/1 project, but future GEM systems GE2/1 and ME0 as well. During the slice test, it was observed that readout channels were being lost in the course of operation to such a degree that the operational lifetime of the system was in serious jeopardy. These losses were attributed to damage to the front-end readout ASIC (VFAT) inputs, caused propagating electrical discharges within the detectors, and a dedicated campaign to study the discharges was launched. The results of this study will be presented in this dissertation. A campaign to mitigate these discharges and their resulting damage was launched. In order to protect the sensitive VFAT from damage, several external protection circuits were proposed and thoroughly tested. The results of these tests, which are presented herein, determined that a series of resistors totaling 470 Ohms would be installed on the VFAT hybrid. When coupled with an additional 200 kOhm resistor on the HV filter, this reduced the probability of damage following a discharge from 93% to 3% As GE2/1 and ME0 are not due to be installed for another few years, more complex discharge-prevention measures can be put into place. As such, the following measures have been examined, and results will be discussed herein: A new, larger VFAT hybrid is being manufactured, whose larger surface area can accommodate more robust protection circuits than those considered and used for GE1/1. As well, double-segmented GEM foils, in which both the top and bottom of each foil is segmented into < 100 cm^2 sectors that are separated by resistors, were examined for use in the detectors. These double-segmented foils were found to introduce a cross-talk signal in the detectors that results in false signals being treated as true signals, which causes a saturation of the GEM bandwidth and results in unwanted dead time. These cross-talk signals, as well as the compromises made to reduce the cross-talk while maintaining robust discharge prevention, will be discussed. / Doctorat en Sciences / info:eu-repo/semantics/nonPublished