Background: Globally 300 000 children are diagnosed with cancer each year and in Sweden, approximately 300 children are affected. Cancer is the largest cause to death among children age 0-19. Children may experience pain, anxiety, and fear. The cancer treatment can cause suffering and making the children more sensitive to infections. Previous research has shown there is a lack of knowledge about nurse's experiences of caring for children diagnosed with cancer. Aim: The aim of this study was to describe nurse's experiences of caring for children diagnosed with cancer. Method: An overview of the literature was performed. Ten qualitative studies were included in the results of this study. Results: The main categories that emerged was: Emotions in caring, the important of involving the child and their parents in the care and the meaning of support in caregiving. Nurses experienced several emotions when caring for children diagnosed with cancer and their families. The nurses were emotionally affected and sometimes they have difficulties coping with these experiences. The relationship with the family was one of the main reasons the nurses appreciated working at oncology unit. Conclusion: The nurses were emotionally affected and experienced both positive and negative emotions. This study showed that family centered care is important that includes an ability to listen and accommodate children's and their family's needs, as well as acknowledge their voices.