Diagnostic biases against individuals of advanced age or few years of formal education exist because age and education are commonly related to performance on cognitive tests, thus, demographic corrections for these tests are used. Corrections are complicated, however, by an association between demographic variables and dementia diagnoses. This dissertation examined the dementia diagnostic accuracy of demographic corrections for cognitive tests. Experiment I tested whether, in the context of skewed tests that violate the statistical assumptions of linearity and homoscedasticity, the accuracy of demographically-corrected test scores would be reduced. Experiment II tested whether demographic corrections would only be appropriate for biased factors instead of the total score for multifactorial tests. Experiment III explored whether demographic corrections would be inappropriate under conditions where the dementia pathology overrides the association between cognitive test scores and demographic variables. Experiment IV explored whether demographic corrections would be inappropriate in conditions where the demographic variables were, in themselves, risk factors for dementia, as this would remove predictive variance. Experiment V explored aspects particular to regression-based demographic corrections that might adversely affect diagnostic accuracy. Experiments I to V were simulation-based; consequently Experiment VI explored replication of these findings using regression adjusted scores in a previously collected clinical database. Finally, Experiment VII used clinical data in conjunction with published clinical normative data with demographic-stratification to test the generalizability of these findings to clinical practice. Using area under the receiver operating characteristic curve comparisons, the use of demographically-corrected scores repeatedly failed to improve upon the dementia diagnostic accuracy of uncorrected cognitive test scores, regardless of whether these corrections were regression-based or based on demographically stratified normative data. Demographic corrections reduced dementia diagnostic accuracy when cognitive test scores were skewed or when adjustments were regression-based and demographic variables were risk factors for dementia. The use of demographic corrections when dementia pathology supersedes any association between cognitive test scores and demographic variables does not impact the relative diagnostic accuracy of demographically-corrected versus uncorrected test scores. Overall, these results suggest that the use of demographic corrections for cognitive test scores is highly cautioned when the goal is to maximize dementia diagnostic accuracy.

This descriptive, exploratory study framed within Parse’s theory of humanbecoming, addressed the research question: What is the meaning of persons’ experiences of keeping in touch with their loved ones who have died. Seven persons described their experiences of keeping in touch with their loved ones who had died. Study themes in the language of the participants were treasured events and signs give rise to lasting comfort while constant yet changing bonds come with turmoil and tranquility amid unfolding strength and confidence. Interpreted in the language of the researcher, study findings were written as cherished ciphers and occurrences engender solace as enduring-shifting ties abide with ease unease amid fortifying expansion. Study themes were linked primarily with theoretical concepts of valuing imaging, connecting-separating, and transforming. Findings were discussed in light of relevant literature, and possibilities for nursing practice, education, policy, and further research were offered.

Memory conformity effects occur when witnesses report misleading suggestions they learned about from another witness. Using a new paradigm the present thesis investigated whether what subject-witnesses report about an event also implies what they personally remember or know about that event. Subjects were tested in pairs, with each member of a pair shown a different version of a video using the MORI technique. There were critical details (e.g., theft of an iPod) in each of the following conditions: visible to only one member of each subject spair, visible to both members of the pair, and not visible to either member of the pair. Pairs subsequently completed a questionnaire together to remember details from the video. Subjects then individually completed a similar questionnaire. A source monitoring and subjective experiences test revealed that co-witness discussion does not necessarily lead people to experience illusory recollections for details they did not witness themselves.

The successful execution of goal-directed movement requires the evaluation of many levels of errors. On one hand, the motor system needs to be able to evaluate ‘high-level’ errors indicating the success or failure of a given movement. On the other hand, as a movement is executed the motor system also has to be able to correct for ‘low-level’ errors - an error in the initial motor command or change in the motor command necessary to compensate for an unexpected change in the movement environment. The goal of the present research was to provide electroencephalographic evidence that error processing during motor control is evaluated hierarchically. The present research demonstrated that high-level motor errors indicating the failure of a system goal elicited the error-related negativity, a component of the event-related brain potential (ERP) evoked by incorrect responses and error feedback. The present research also demonstrated that low-level motor errors are associated with parietally distributed ERP component related to the focusing of visuo-spatial attention and context-updating. Finally, the present research includes a viable neural model for hierarchical error processing during motor control.

Diagnostic biases against individuals of advanced age or few years of formal education exist because age and education are commonly related to performance on cognitive tests, thus, demographic corrections for these tests are used. Corrections are complicated, however, by an association between demographic variables and dementia diagnoses. This dissertation examined the dementia diagnostic accuracy of demographic corrections for cognitive tests. Experiment I tested whether, in the context of skewed tests that violate the statistical assumptions of linearity and homoscedasticity, the accuracy of demographically-corrected test scores would be reduced. Experiment II tested whether demographic corrections would only be appropriate for biased factors instead of the total score for multifactorial tests. Experiment III explored whether demographic corrections would be inappropriate under conditions where the dementia pathology overrides the association between cognitive test scores and demographic variables. Experiment IV explored whether demographic corrections would be inappropriate in conditions where the demographic variables were, in themselves, risk factors for dementia, as this would remove predictive variance. Experiment V explored aspects particular to regression-based demographic corrections that might adversely affect diagnostic accuracy. Experiments I to V were simulation-based; consequently Experiment VI explored replication of these findings using regression adjusted scores in a previously collected clinical database. Finally, Experiment VII used clinical data in conjunction with published clinical normative data with demographic-stratification to test the generalizability of these findings to clinical practice. Using area under the receiver operating characteristic curve comparisons, the use of demographically-corrected scores repeatedly failed to improve upon the dementia diagnostic accuracy of uncorrected cognitive test scores, regardless of whether these corrections were regression-based or based on demographically stratified normative data. Demographic corrections reduced dementia diagnostic accuracy when cognitive test scores were skewed or when adjustments were regression-based and demographic variables were risk factors for dementia. The use of demographic corrections when dementia pathology supersedes any association between cognitive test scores and demographic variables does not impact the relative diagnostic accuracy of demographically-corrected versus uncorrected test scores. Overall, these results suggest that the use of demographic corrections for cognitive test scores is highly cautioned when the goal is to maximize dementia diagnostic accuracy.

Die Fragestellung dieser Arbeit ist ob derzeit angebotene e-Government Systeme von älteren Nutzern angenommen werden und wie solche aufgebaut werden müssen, damit diese Nutzergruppe solche Systeme als eine nützliche Alternative zu Behördengängen annimmt. In unserer Forschung haben wir erforscht wie solche Anwendungen, welche von der Verwaltung für die gesamte Bevölkerung angeboten werden, aufgebaut werden sollten, damit diese von der gesamten Bevölkerung erfolgreich genutzt werde können. Zur Beantwortung dieser Fragestellung wurde eine dreistufige Forschung durchgeführt, welche an das ISO 9241-210 Entwicklungsmodell angelehnt ist. Die Forschung wurde parallel in Deutschland und Ungarn in Kooperation mit dem Fraunhofer FOKUS, dem Bundesministerium des Innern, der Bundesdruckerei und der Corvinus Universität Budapest durchgeführt. In der ersten Phase wurden die Erwartungen und Vorkenntnisse der Zielgruppe erforscht um die Eckpunkte und Prämissen festlegen zu können. Diese Erkenntnisse ermöglichten in der zweiten Phase die fundierte Auswahl einer Anwendung, welche als Basis für Nutzertests genutzt werden konnte. Die Testanwendung war das AusweisApp des elektronischen Personalausweises. Bei diesen Tests wurden die Nutzerfehler erfasst und die Akzeptanz durch die ASQ Methode gemessen. Anhand der gewonnen Erkenntnisse konnte die Guideline IGUAN entwickelt werden, welche eine standardisierte Herangehensweise zur Akzeptanzsteigerung darstellt. Dieses Konzept beinhaltet neben den speziellen, an ältere Nutzer angepassten Anforderungen, einem Kriterienkatalog, sowie die Abbildung der Prozesse wodurch eine Erhöhung der Akzeptanz für Ältere ermöglicht wird. In der dritten Phase der Forschung konnte die Guideline durch eine iterative Prototypentwicklung evaluiert und geprüft werden. Wir konnten beweisen, dass Verbesserungen beim Interface e-Government Anwendungen an die alternde Gesellschaft näher bringen, die Motivation erhöhen und das Nutzerempfinden nachhaltig verbessern. / Our research focuses on the question of acceptance of current e-government systems by elderly users. It describes how such systems should be designed and offered for this user group in order to provide an acceptable alternative to offline processes. In order to answer our research question, the research was structured into three phases along the development model of the ISO 9241-210. This enabled to identify not only the main factors of acceptance, but also the expectations of elderly users. Our research was conducted in parallel in Germany and Hungary in cooperation with the Fraunhofer FOKUS, the Federal Ministry of Interior, the Bundesdruckerei and the Corvinus University Budapest. The first phase of our research provided results about the expectations and previous experience of the users with e-government systems. This set the premises for the next phases of our research and provided us with information about the theoretical acceptance of systems by the age group. The results made it possible to select an application in the second phase, which was used as a model in the remaining phases. The selected application was the AusweisApp of the electronic ID card. The test measured the encountered errors and the acceptance of the system with the ASQ method. The obtain results allowed us to develop a generalised solution, the IGUAN guideline. This guideline makes a standardised approach to the usability improvement process possible. It contains the special requirements of elderly users, and a catalogue of criteria, which helps to develop an application in line with the set requirements. The third phase of our research was used a proof of concept for the IGUAN. The guideline was evaluated and tested with an iterative prototyping. We could therefore demonstrate that improvements in the interface make e-government application possible which are perceived useful and easy to use by elderly users. These improvements will measurably increase the user motivation and experience.

We have investigated the feasibility of using digital tabletop displays during design team meetings to improve access to design information. To achieve this goal, we have applied various design guidelines for tabletop interface design and requirements for digital meeting scenarios in order to implement design ideas (in a prototype named Mozaic) that specifically cater to design team meetings. Mozaic intends to improve information retrieval and browsing activities during meetings thereby improving information access through a tile based layout, pop-up menu control and filtered list. We have evaluated the features of Mozaic through an exploratory study on a tabletop display (in comparison to a commonly used desktop software tool, which was also used on the tabletop) to evaluate various design ideas and ferret out design ideas for future iterations of Mozaic. We present the result of this study as observations and user feedback and discuss them in the light of interface development for design meeting situations.