Global ETD Search

601	Glycoprotein hormone expression in the anterior pituitary Aylwin, Simon John Byng January 2001 (has links) No description available. 572
602	Differentiation of neuroblastoma cell line B104 and characterisation of its ability to support HSV-1 replication Homer, Elizabeth Gene January 1994 (has links) No description available. 579
603	A study of lactate dehydrogenase from Plasmodium falciparum Higham, Christopher W. January 1999 (has links) No description available. 572
604	Neurotrophic factors : production and purification of neurotrophic factor receptors using a baculovirus expression system Ashcroft, Margaret January 1995 (has links) No description available. 610.28 Protein expression; Nerve growth factor
605	Functional characterisation of GCR1, a G protein-coupled receptor from Arabidopsis thaliana Couch, Daniel Charles January 2001 (has links) No description available. 572.8
606	Formalising CORE requirements Smith, Lindsey C. January 1993 (has links) No description available. 005
607	Differential gene expression in TPA responsive and non-responsive mouse fibroblasts. Stuiver, Ingrid January 1992 (has links) Our laboratory has previously isolated a 12-O-tetradecanoylphorbol-13-acetate (TPA)-nonresponsive variant line (VT-1) from mouse 3T3-L1 cells. Here the expression of type I collagen pro-α2 (pro-α2(I)) mRNA and production of type I collagen in these two cell lines is examined. In quiescent cells, the pro-α2(I) steady state mRNA levels were 4 times greater in 3T3-L1 cells than in VT-1 cells. TPA addition caused the steady-state levels of pro-α2(I) mRNA to be 6 times greater in 3T3-L1 cells than in VT-1 cells. The pro-α2(I) protein levels in the extracellular matrix or culture media of 3T3-L1 cells were substantially elevated by TPA treatment but no significant increase was detected in VT-1 cells. The correlation of collagen expression with a TPA-mediated mitogenic response suggests a new role for collagen as an early component of mitogenic signal transduction. Expression of protooncogenes and other mitogenically related genes were also examined in 3T3-L1 and VT-1 cells. c-fos, c-myc, c-jun and ornithine decarboxylase were expressed in both cell lines. These findings suggest that expression of these genes may be necessary but not sufficient for a TPA induced mitogenic response. Two of the TPA Inducible Early (TIE) genes selected had no homology with any other known sequence. Here, mRNA expression levels of these novel genes (TIE-10B and TIE-44) are examined in 3T3-L1 and VT-1 cells and in several mouse tissues. Within 30 minutes of TPA treatment, TIE gene mRNA is increased in 3T3-L1 cells; whereas, with the exception of TIE-10B, low levels or delayed mRNA expression is seen in VT-1 cells. The two genes are expressed in most mouse tissues tested. mRNA levels of both TIE genes also increased in response to serum supplemented medium. Typical mRNA expression patterns for protooncogenes c-fos, c-myc, c-jun are seen when cells are treated with TPA or serum-supplemented media. The differential mRNA expression of the TIE genes relative to other growth potentiating genes and in response to mitogens other than TPA is indicative of the complexity and wide range of genes involved in several possible pathways leading to the cells' mitogenic response. (Abstract shortened with permission of author.) Dissertations, Academic. Molecular biology. Gene expression.
608	The role of matrix metalloproteinases and their inhibitors, the tissue inhibitors of metalloproteinases, in renal cell carcinoma cell invasion and metastasis McElligott, Anthony Morgan January 1999 (has links) No description available. 572.8
609	Induction of immunity in mice exposed to Schistosoma mansoni Shires, Virginia Louise January 2000 (has links) No description available. 579
610	Wound signalling Arabidopsis thaliana Brickell, Laura January 1999 (has links) No description available. 572.8 Plane defence; Gene expression; Ethylene

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