Thesis (M.S.)--University of Calif. 1912. / Reprint from the Public health reports, vol. XXVII, no. 36, Sept. 6, 1912. This paper originally appeared in the Military surgeon, vol. XXIX, no. 6, Dec. 1911, p. 631-657, under title, "The problem of Rocky Mountain spotted fever." As republished here the text and bibliography have been amended so as to cover the subject to the present time. cf. p. 3. Bibliography: p. 23-29.

Considerable research on ticks has been done since it was discovered that the Rocky Mountain wood tick, Dermacentor andersoni Stiles, was a principal vector of Rocky Mountain spotted fevero Additional disease agents of man are also transmitted by D. andersoni. This tick and a closely related species, Dermacentor parumapertus Neuman, occur commonly in Utah. The two species are often closely associated, although D. andersoni is believed to occur in the mountains, whereas D. parumapertus is in the desert valleys. Diseases affecting animals in nature are transmitted by ticks of both species. Consequently, any interaction between the two may be influential in the maintenance of diseases in nature communicable to man and his domestic animals.

Neste projeto, objetivou-se o diagnóstico de riquétsias, utilizando metodologia molecular, em material de humanos, carrapatos, pulgas, cães e equinos de áreas endêmicas dos estados de São Paulo (SP) e Rio de Janeiro (RJ). Diagnosticou-se Rickettsia rickettsii infectando Amblyomma cajennense e humanos no estado de SP, indicando ser esta a única espécie responsável pela doença. Rickettsia conorii foi diagnosticada em um paciente procedente de Portugal. No estado do RJ, Rickettsia felis foi detectada Ctenocephalides felis e em Am. cajennense enquanto que R. rickettsii em Amblyomma aureolatum, Am. cajennense, Anocentor nitens, Boophilus microplus, Ct. felis e Rhipicephalus sanguineus. As frequências mínimas de vetores infectados do estado do RJ apresentaram valores superiores àqueles registrados em outras regiões do país. Demonstrou-se, de forma inédita, o envolvimento de algumas destas espécies no ciclo da bactéria. R. rickettsii foi diagnosticada em cães e equinos indicando a importância dos animais domésticos na manutenção do ciclo da riquetsiose. / This project aimed to diagnose rickettsial diseases using molecular analysis methods on human, tick, flea, dog and horse samples from endemic areas in the States of São Paulo (SP) and Rio de Janeiro (RJ). A diagnosis of Rickettsia rickettsii infecting Amblyomma cajennense and humans in the State of SP was made, indicating that this is the only species responsible for the disease. Rickettsia conorii was diagnosed in a patient from Portugal. In RJ, Rickettsia felis was detected in Ctenocephalides felis and Am. cajennense, while R. rickettsii was detected in Amblyomma aureolatum, Am. cajennense, Anocentor nitens, Boophilus microplus, Ct. felis and Rhipicephalus sanguineus. In the State of RJ the minimum frequency of infected vectors presented higher values than those recorded in other regions of the country. The involvement of some of these species in the bacterium cycle has been demonstrated for the first time. R. rickettsii was diagnosed in dogs and horses indicating the importance of livestock in the maintenance cycle of rickettsial infection.

Neste projeto, objetivou-se o diagnóstico de riquétsias, utilizando metodologia molecular, em material de humanos, carrapatos, pulgas, cães e equinos de áreas endêmicas dos estados de São Paulo (SP) e Rio de Janeiro (RJ). Diagnosticou-se Rickettsia rickettsii infectando Amblyomma cajennense e humanos no estado de SP, indicando ser esta a única espécie responsável pela doença. Rickettsia conorii foi diagnosticada em um paciente procedente de Portugal. No estado do RJ, Rickettsia felis foi detectada Ctenocephalides felis e em Am. cajennense enquanto que R. rickettsii em Amblyomma aureolatum, Am. cajennense, Anocentor nitens, Boophilus microplus, Ct. felis e Rhipicephalus sanguineus. As frequências mínimas de vetores infectados do estado do RJ apresentaram valores superiores àqueles registrados em outras regiões do país. Demonstrou-se, de forma inédita, o envolvimento de algumas destas espécies no ciclo da bactéria. R. rickettsii foi diagnosticada em cães e equinos indicando a importância dos animais domésticos na manutenção do ciclo da riquetsiose. / This project aimed to diagnose rickettsial diseases using molecular analysis methods on human, tick, flea, dog and horse samples from endemic areas in the States of São Paulo (SP) and Rio de Janeiro (RJ). A diagnosis of Rickettsia rickettsii infecting Amblyomma cajennense and humans in the State of SP was made, indicating that this is the only species responsible for the disease. Rickettsia conorii was diagnosed in a patient from Portugal. In RJ, Rickettsia felis was detected in Ctenocephalides felis and Am. cajennense, while R. rickettsii was detected in Amblyomma aureolatum, Am. cajennense, Anocentor nitens, Boophilus microplus, Ct. felis and Rhipicephalus sanguineus. In the State of RJ the minimum frequency of infected vectors presented higher values than those recorded in other regions of the country. The involvement of some of these species in the bacterium cycle has been demonstrated for the first time. R. rickettsii was diagnosed in dogs and horses indicating the importance of livestock in the maintenance cycle of rickettsial infection.