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Piggybacking Fischer carbene complexesHarris, Nora-ann January 2013 (has links)
Please read the abstract in the dissertation / Dissertation (MSc)--University of Pretoria, 2013. / gm2014 / Chemistry / Unrestricted
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The Synthesis of Fischer carbene complexes with metal-containing substituentsVan der Walt, Elisia 22 February 2007 (has links)
See Abstract on Front Page 7 / Dissertation (MSc (Chemistry))--University of Pretoria, 2007. / Chemistry / unrestricted
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Synthesis Of Ferrocenyl CyclopentenonesTumay, Tulay Asli 01 August 2005 (has links) (PDF)
ABSTRACT
SYNTHESIS OF FERROCENYL CYCLOPENTENONES
TUMAY, Tü / lay Asli
M.S., Department of Chemistry
Supervisor: Assoc. Prof. Dr. Metin Zora
August 2005, 80 pages
Construction of highly functionalized five-membered rings via cycloaddition reaction of cyclopropylcarbene-chromium complex with alkynes has become a very active area of research in recent years by virtue of their presence in antitumour natural products. Also with the finding that ferrocene derivatives are active against various tumours, considerable interest has been devoted to the synthesis of new ferrocene derivatives since properly functionalized ferrocene derivatives could be potential antitumour substances. So, the incorporation of the essential structural features of cyclopentenones with a ferrocene moiety could provide compounds with enhanced antitumour activities. For this purpose, we have investigated the reaction between cyclopropylcarbene-chromium complex and ferrocenyl alkynes.
The reaction of cyclopropylcarbene-chromium complex with ferrocenyl alkynes afforded & / #945 / -hydroxycyclopentenones in a one-pot process, whereas the same reaction with alkynes gave cyclopentenones as major products.
Interestingly, water addition was observed instead of reduction according to the previously proposed mechanism. This is a different result than those in literature.
The reaction was regioselective both with terminal ferrocenyl alkynes and internal unsymmetrical ferrocenyl alkynes. The products obtained were those where the sterically larger alkyne substituent, ferrocene, was & / #945 / to the carbonyl group.
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β-Aminosubstituted α,β-Unsaturated Fischer Carbene Complexes as Precursors for Complex Oligocyclic Molecules - Basics and Applications / β-Amino-substituierte α,β-Ungesättigte Fischer Carben-Komplexeals Vorläufer für Kompexe Oligocyclische Moleküle - Grundforschung und AnwendungenWu, Yao-Ting 03 July 2003 (has links)
No description available.
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