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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

The synthesis of mono-amino-flavones of flavone-azobeta-naphththol dyes and of other flavone derivatives ...

Marcus, Joseph K., January 1900 (has links)
Thesis (Ph. D.)--Columbia University, 1918. / Biographical. Bibliography: p. 37.
2

The synthesis of mono-amino-flavones, of flavone-azobeta-naphththol dyes and of other flavone derivatives ...

Marcus, Joseph K., January 1900 (has links)
Thesis (Ph. D.)--Columbia university, 1918. / Biographical. Bibliography: p. 37.
3

Pharmacokinetic and pharmacodynamic investigations of selected chiral flavonoids

Vega-Villa, Karina R. January 2009 (has links) (PDF)
Thesis (Ph. D.)--Washington State University, May 2009. / Title from PDF title page (viewed on June 1, 2009). "College of Pharmacy." Includes bibliographical references (p. 266-283).
4

Structural activity relationship of flavonoids on endothelial nitric oxide expression

張凱德, Cheung, Hoi-tak. January 2008 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
5

Structural activity relationship of flavonoids on the expression and activity of cyclooxygenase

Leung, Pui-hong., 梁沛康. January 2009 (has links)
published_or_final_version / Pharmacology and Pharmacy / Master / Master of Medical Sciences
6

Interactions of Azorhizobium caulinodans with Brassica napus and Arabidopsis thaliana

Stone, Philip John January 2001 (has links)
No description available.
7

Studies on the 2-oxoglutarate dependent oxygenases of flavonoid biosynthesis

Turnbull, Jonathan J. January 2003 (has links)
No description available.
8

Effect of different flavonoids on activation of cyclooxygenase pathwayby phorbol 12-myristate 13-acetate (PMA) in endothelial cells

Ma, King-hong., 馬景康. January 2011 (has links)
published_or_final_version / Pharmacology / Master / Master of Medical Sciences
9

Structural characterization of isomeric flavonoid glycosides and metabolites by metal complexation and electrospray ionization tandem mass spectrometry

Davis, Barry D., 1976- 28 August 2008 (has links)
Flavonoids form a vast group of natural products that occur ubiquitously throughout the plant kingdom. These compounds play a significant role in the field of phytochemistry and are of nutritional interest due to numerous reports of their benefits to human health. Structural characterization of individual flavonoid derivatives is challenging because of widespread isomerism and a lack of sensitive and specific analytical techniques. The goal of this work is to present practical tandem mass spectrometry methods for systematic isomer differentiation of flavonoid glycosides and flavonoid glucuronides. Metal complexation is used extensively as a strategy to achieve this aim. In this approach, flavonoid derivatives and metal ions are mixed in solution, resulting in the rapid self-assembly of complexes which are subsequently infused into a quadrupole ion trap mass spectrometer. Collision-induced dissociation of these flavonoid/metal complexes results in fragment ions that are highly characteristic of specific structural features of the flavonoid derivatives. These methods are adaptable to LC-MS analysis via post-column addition of the complexation reagents. Methods to differentiate the five most common glycosylation sites of monoglucosyl flavonoids are described. Based on the fragment ions yielded from magnesium or manganese complexes, specific indicators of 3-O-glucosylation, 7-O-glucosylation, 4'-O-glucosylation, 6-C-glucosylation and 8-C-glucosylation are observed. The manganese complexation method also differentiates isomeric glucose and galactose sugars at the 3 position, as well as arabinose and xylose sugars. Differentiation of isomeric flavonoid glucuronide metabolites is achieved by cobalt complexation with auxiliary ligands. The effectiveness of these methods is proven in numerous practical applications. Flavonoid glycosides are identified in extracts from apples, onions, and Silphium albiflorum. Flavonoid glucuronide metabolites are identified in urine samples and a cell culture extract. The identifications are achieved without the use of standards or additional analytical techniques. Finally, an enzymatic synthesis of flavonoid glucuronides is used to establish the regioselectivity of UGT1A1, an enzyme involved in flavonoid metabolism. The cobalt complexation method successfully identifies many hitherto uncharacterized metabolites. The significance of this work lies in its potential application to problems in botanical, agricultural, nutritional and disease-prevention studies in which precise flavonoid identification is required.
10

Biological properties of selected flavonoids of rooibos (Aspalathus linearis).

Snijman, Petra Wilhelmina. January 2007 (has links)
<p>Bioactivity-guided fractionation was used to identify the most potent antioxidant and antimutagenic fractions contained in the methanol extract of unfermented rooibos (Aspalathus linearis), as well as the bioactive principles for the most potent antioxidant fractions. The aim of this thesis was to investigate whether the same flavonoids are responsible for both the potent antioxidant and antimutagenic properties of unfermented rooibos.</p>

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