Background: The nurses’ responsibility is to give good and safe health care based on nursing science and proved practice, and also keeping up to date with the latest nursing science. The most common use of research utilization is instrumental, which is nursing science directly applied when caring for patients. By acquiring and utilizing new nursing science, the nurse is able to develop safe care for patients.  Aim: The aim of this review was to describe nurses’ perceptions of implementing research science in clinical practice. Method: A literary review based on studies acquired from the database CINAHL Complete and Academic Search Complete  Result: The impact of nursing science describes that nurses believe nursing science as important for the evolvement and quality of the profession, but perceives it to be too complex to utilize. Nurses’ perceptions of barriers and facilitators towards research utilization in nursing science describe what organizational factors affect nurses´ perceptions of research utilization in nursing care. Nurses also describe that they want to utilize research, but they lack the skill to critically appraise scientific literature. Lack of time and low research availability are described as barriers towards research, and support and engagement from nursing administrators are considered a facilitator towards better research utilization. Discussion: Despite having a positive attitude towards nursing science, the result shows that the nurses today find it difficult to implement it in a clinical practice. The results indicate that there needs to be support from the management to facilitate research utilization in a clinical practice.