Global ETD Search

11	Signaling pathways regulating endothelial cell survival and activation / Li, Xianwu. January 2003 (has links) Thesis (Ph. D.)--University of Washington, 2003. / Vita. Includes bibliographical references (leaves 107-130).
12	The role of Rac1 in mouse podocyte cellular process formation and differentiation / Attias, Ortal. January 2008 (has links) The role of podocytes in glomerular permselectivity is tightly associated with their intricate morphology, featuring interdigitating foot processes from adjacent cells. The actin cytoskeleton is an integral component of podocyte foot processes and is regulated by a number of proteins expressed in podocytes. Rho-family of small GTPases are known key regulators of the actin cytoskeleton. This study, investigated the role of Rac1 in podocytes, using conditionally immortalized mouse podocytes (MPs). We studied Rho-GTPase activities and morphology/cytoskeleton of differentiating mouse podocytes stably expressing nephrin. We also studied the impact of transfection of various Rho-GTPase mutants and IQGAP1 mutants. We demonstrated that nephrin expression potentiates and sustains Rac1 activity during the differentiation process. We showed that Rac1 contributes to process formation in differentiating MPs and may have a similar role in vivo when podocytes are recovering from injuries. Podocytes -- physiology. Podocytes -- ultrastructure. rac1 GTP-Binding Protein -- metabolism. Mice, Transgenic. Mice.
13	Systems analysis of nuclear transport / Riddick, Gregory Parker. January 2008 (has links) Thesis (Ph. D.)--University of Virginia, 2008. / Includes bibliographical references. Also available online through Digital Dissertations.
14	Dynamic changes in T cell compartments and new approaches in evaluating DSS induced and Galfai2 deficient colitis / Fritsch Fredin, Maria, January 2007 (has links) Diss. (sammanfattning) Göteborg : Univ., 2007. / Härtill 4 uppsatser.
15	The regulation of T-type calcium channels by G protein [beta][gamma] dimers / DePuy, Seth David. January 2007 (has links) Thesis (Ph. D.)--University of Virginia, 2008. / Includes bibliographical references. Also available via the Internet as viewed 10 July 2008.
16	The role of the RhoGEF Trio in brain development Ghogha, Atefeh. January 1900 (has links) Thesis (M.Sc.). / Written for the Dept. of Anatomy and Cell Biology. Title from title page of PDF (viewed 2008/05/14). Includes bibliographical references.
17	Identification and characterization of a NEF associated kinase Arora, Vivek Kumar. January 2002 (has links) (PDF) Thesis (Ph. D.) -- University of Texas Southwestern Medical Center at Dallas, 2002. / Vita. Bibliography: 116-128.
18	Allosteric determinants of guanine nucleotide binding proteins and methods to crystallize the cytosolic domains of adenylyl cyclase Hatley, Mark Edward. January 2004 (has links) (PDF) Thesis (Ph. D.) -- University of Texas Southwestern Medical Center at Dallas, 2004. / Vita. Bibliography: 154-163.
19	Biochemical and biophysical characterization of the allosteric equilibrium of the Wiskott-Aldrich Syndrome protein Leung, Daisy W. January 2005 (has links) Thesis (Ph.D.) -- University of Texas Southwestern Medical Center at Dallas, 2005. / Embargoed. Vita. Bibliography: References located at the end of each chapter.
20	Regulation of nuclear transport and mitosis by Ran GTPase / Chen, Ting. January 2007 (has links) Thesis (Ph. D.)--University of Virginia, 2007. / Includes bibliographical references. Also available online through Digital Dissertations.

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