Ipsilateral pulmonary edema may occur in a lung that has been rapidly reinflated after a period of collapse. The syndrome of re-expansion pulmonary edema is associated with variable degrees of hypotension and hypoxemia. In its extreme form, it may result in cardiac arrest and death. The initial cause of uninflated pulmonary parenchyma described with re-expansion pulmonary edema has typically been either a large undrained pleural effusion or a pneumothorax. The authors describe a patient in whom re-expansion pulmonary edema developed when inadvertent puncture of large emphysematous bullae released previously atelectatic lung.

Introduction: There are no validated strategies in the teaching of ultrasound as a diagnostic tool in undergraduate medicine students. Given the role that ultrasound plays in the diagnostic capacity of any clinician is currently undeniable, a teaching method is proposed based on the demonstration of the association between the histopathology of a large vessel vasculitis and the characteristic ultrasound finding, known as the «halo sign». Methods: The teaching strategy was imparted by means of a 10-minute video presentation. Twenty-one final-year students from a single medical school participated in a concordance study and a validation test, identifying images corresponding to the halo sign in 120 different cases. The overall sensitivity, specificity and likelihood ratio of the students were also determined. Results: The overall concordance test had a kappa coefficient of 0.749 (SD: 0.11). The kappa concordance was 0.76 with dynamic images, and 0.84 with cross-sectional slices. The overall sensitivity was 89.7%, and the positive predictive value was 92.3%. The likelihood ratio achieved was 7.28. Conclusions: It has been shown that the application of this pedagogical method is useful in teaching the identification of an ultrasound sign to medical students. This study also suggests conditions that could be useful to improve between-observer agreement in both teaching scenarios and multiple observer scientific studies. / Revisión por pares

No description available.

This study investigated the morphologic differences of the giant vacuoles (GVs) in the inner wall endothelium of Schlemm’s canal (SC) in human eyes perfused at either 30 mmHg or 7 mmHg (physiologic pressure in enucleated eyes) using serial block-face scanning electron microscopy (SBF-SEM) paired with three-dimensional reconstruction software. Two normal human eyes were perfused at 30 mmHg with fluorescent tracers to mark regions of active and inactive flow, followed by perfusion-fixation. Tissue wedges (n = 6) of trabecular meshwork including SC from high-, low-, and non-flow areas of each eye (determined by tracer distribution) were dissected and processed for SBF-SEM. Four types of GVs were identified: Type I GVs which lack both a basal opening and an Ipore; Type II GVs which have a basal opening but lack an I-pore; Type III GVs which have an I-pore but lack a basal opening; and Type IV GVs which possess both a basal opening and an I-pore. Types and spans of GVs were collected from the SBF-SEM images, and volumes of GVs from a random subset were measured using 3D reconstruction. Results were compared with findings from an earlier study conducted with two eyes perfused at 7 mmHg and prepared in the same manner (Soares, 2022). In total, 19,047 SBF-SEM images were analyzed between 7 mmHg (n = 9586) and 30 mmHg (n = 9461) using Reconstruct. Statistical analysis comparing data between the two pressures was performed using R. There were more GVs found at 30 mmHg (n = 1541) when compared with 7 mmHg (n = 1312), and there were more Type IV GVs at 30 mmHg when compared with 7 mmHg. Type IV GVs occurred most frequently in high-flow areas at both pressures. GVs with I-pores were greater in size (both span and volume) than GVs without I-pores in all flow areas at both pressures. Type IV GVs were larger than Type II GVs which were larger than Type I GVs at both pressures. The span of GVs without I-pores was significantly greater at 7 mmHg. However, there was no significant difference between the volumes of GVs with or without I-pores between the two pressures. The result that GVs with I-pores were larger in size than GVs without I-pores at all conditions appears to support the theory that GV size is an important contributing factor to I-pore formation. The differences in span but not volume of GVs without I-pores between two pressures suggest that GVs at high pressure may be more convex in shape and may protrude further into SC, a situation which could contribute to thinning of the cellular membrane of GVs. Finally, the result that more Type IV GVs were found in high-flow areas at both pressures implies that the changing percentage of Type IV GVs likely plays a role in regulating segmental flow. / 2025-02-26T00:00:00Z

No description available.

El Tumor de Células Gigantes es un tumor de comportamiento localmente agresivo y que asienta a nivel óseo próximo a las articulaciones en pacientes jóvenes. La larga trayectoria en el tratamiento de los tumores óseos en el Hospital Universitario Virgen de la Arrixaca y la controversia actual en el diagnóstico y tratamiento de este tumor nos llevó a realizar esta Memoria. Todos los pacientes de la serie fueron sometidos a una completa anamnesis y exploración física y se cuantificaron los intervalos transcurridos desde la aparición de los síntomas, momento de consulta, diagnóstico y tratamiento. Se valora las técnicas diagnósticas empleadas, así como el tratamiento quirúrgico bien mediante procedimiento intralesional o resección amplia y las técnicas de reconstrucción. Se estudia la integración de los aloinjertos estructurales mediante la escala ISOLS y la integración del aloinjerto triturado mediante la escala VIIT. También se valora los resultados funcionales mediante la escala EFCOM. / Giant cell tumor is a locally aggressive bone tumor and it is located in the end of the long bones near of joints in young patients. The long history in the treatment of bone tumors at the Hospital Universitario Virgen de la Arrixaca and the current controversy in the diagnosis and treatment of this tumor led us to this report. All patients in the series underwent a complete history and physical examination and quantified the interval since the onset of symptoms, time of consultation, diagnosis and treatment. It assesses the diagnostic techniques used and the surgical procedure or by intralesional or wide resection and reconstruction techniques. We study the integration of structural allografts by ISOLS scale and integration of crushed allografts by the VIIT scale. It also assesses the functional results by EFCOM scale.

No description available.

Thesis (Ph. D.)--University of Washington, 2000. / Vita. Includes bibliographical references (leaves 118-131).

In the widely accepted core accretion model of planet formation, small rocky and/or icy bodies (planetesimals) accrete to form protoplanetary cores. Gas giant planets are believed to have solid cores that must reach a critical mass, ∼10 Earth masses (ME), after which there is rapid inflow of gas from the gas disk. In order to accrete the gas giants’ massive atmospheres, this step must occur within the gas disk’s lifetime (1 − 10 million years). Numerical simulations of solid body accretion in the outer Solar System are performed using two integrators. The goal of these simulations is to investigate the effects of important dynamical processes instead of specifically recreating the formation of the Solar System’s giant planets. The first integrator uses the Symplectic Massive Body Algorithm (SyMBA) with a modification to allow for planetesimal fragmentation. Due to computational constraints, this code has some physical limitations, specifically that the planetesimals themselves cannot grow, so protoplanets must be seeded in the simulations. The second integrator, the Lagrangian Integrator for Planetary Accretion and Dynamics (LIPAD), is more computationally expensive. However, its treatment of planetesimals allows for growth of potential giant planetary cores from a disk consisting only of planetesimals. Thus, this thesis’ preliminary simulations use the first integrator to explore a wider range of parameters while the main simulations use LIPAD to further investigate some specific processes. These simulations are the first use of LIPAD to study giant planet formation and they identify a few important dynamical processes affecting core formation. Without any fragmentation, cores tend to grow to ∼2ME. When planetesimal fragmentation is included, the resulting fragments are easier to accrete and larger cores are formed (∼4ME). But, in half of the runs, the fragments force the entire system to migrate towards the Sun. In other half, outward migration via scattering off a large number of planetesimal helps the protoplanets grow and survive. However, in a preliminary set of simulations including protoplanetary fragmentation, very few collisions are found to result in accretion so it is difficult for any cores to form. / Thesis (Master, Physics, Engineering Physics and Astronomy) -- Queen's University, 2012-08-20 14:48:39.443

The giant panda (Ailuropoda melanoleuca) is an endangered species and many efforts are being made to ensure its survival, including numerous research studies. However, there has been little investigation of spatial memory in the giant panda. Spatial memory is an important mechanism for survival in the wild, allowing an animal to find and remember the location of food, mates, den sites and avoid predators. Memory assessment in non-human species typically involves the use of recognition, as opposed to recall tasks. The current study tested spatial memory recall in 1.1 giant pandas using a delayed response memory task. The design required a delayed response to a previously lighted location, with varying lengths of delay between the observation phase and the test phase. The male subject reached criterion at 2-, 3-, 4-, 5-, 6-, and 10-second delays. The female subject reached criterion at 2-, 3-, 4-, 5-, 6-, 10-, and 15-second delays. The results support the hypothesis that giant pandas have working memory recall ability for spatial location.