Submitted by Alison Vanceto (alison-vanceto@hotmail.com) on 2017-08-24T12:16:41Z No. of bitstreams: 1 DissROM.pdf: 1802563 bytes, checksum: 8a20822e115118f79c74001c251e9156 (MD5) / Approved for entry into archive by Ronildo Prado (ronisp@ufscar.br) on 2017-09-05T19:51:30Z (GMT) No. of bitstreams: 1 DissROM.pdf: 1802563 bytes, checksum: 8a20822e115118f79c74001c251e9156 (MD5) / Approved for entry into archive by Ronildo Prado (ronisp@ufscar.br) on 2017-09-05T19:51:38Z (GMT) No. of bitstreams: 1 DissROM.pdf: 1802563 bytes, checksum: 8a20822e115118f79c74001c251e9156 (MD5) / Made available in DSpace on 2017-09-05T19:57:23Z (GMT). No. of bitstreams: 1 DissROM.pdf: 1802563 bytes, checksum: 8a20822e115118f79c74001c251e9156 (MD5) Previous issue date: 2017-02-15 / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / Objective: The aim of the present study was to investigate associations between abdominal obesity/dynapenia/dynapenic abdominal obesity and a single fall/recurrent falls as well as determine the effect size of such associations using two cutoff points for dynapenia. Methods: A cross-sectional study was conducted with 1.063 older adults pertaining to the third wave of the Saúde, Bem Estar e Envelhecimento (SABE – Health, Wellbeing and Ageing) study. Abdominal obesity was defined as a waist circumference of >102 cm for men and > 88 cm for women. The following were the cutoff points for dynapenia: grip strength < 30 kg for men and < 20 kg for women or < 26 kg for men and < 16 kg for women. Dynapenic abdominal obesity was defined by the combination of abdominal obesity and dynapenia. Regarding the outcome, the individuals were classified as non-fallers, single fallers or recurrent fallers. Socioeconomic, neuropsychiatric and environmental factors as well as living habits, polypharmacy, health status and functionality were the control variables in the multinomial regression models. Results: Adopting a cutoff point of 30/20, only one association was found: dynapenic abdominal obesity and a single fall (RRR = 2.37; 95% CI: 1.48-3.80). However, adopting a cutoff point of 26/16, dynapenic abdominal obesity (RRR = 1.93; 95% CI: 1.09-3.44), abdominal obesity (RRR = 1.65; 95% CI: 1.08-2.52) and dynapenia (RRR = 1.77; 95% CI: 1.01-3.13) were associated with a single fall, with a larger effect size of the association with dynapenic abdominal obesity than the other two conditions. Moreover, dynapenia defined using the 26/16 cutoff point was associated with recurrent falls (RRR = 2.39; 95% CI: 1.19-4.82). Conclusions: The cutoff point used to define dynapenia affects associations between abdominal obesity/dynapenia/dynapenic abdominal obesity and a single fall/recurring falls. A cutoff point of 26/16 is better for identifying such associations. / Objetivo: Investigar a associação de obesidade abdominal (OA), dinapenia e obesidade abdominal dinapênica (OA/D) com queda única e quedas recorrentes, assim como o tamanho do efeito de tais associações, adotando duas notas de cortes para dinapenia. Método: Estudo transversal com 1.063 idosos provenientes da terceira onda do Estudo SABE. OA foi definida como circunferência de cintura > 102 cm para homens e > 88 cm para mulheres. As notas de corte para dinapenia foram: força de preensão manual < 30 kg para homens e < 20 kg para mulheres ou < 26 kg para homens e < 16 kg para mulheres. OA/D foi definida pela associação de OA e dinapenia. Quanto ao desfecho, os idosos foram classificados como não caidores, caidores únicos ou recorrentes. Fatores socioeconômicos, neuropsiquiátricos, ambientais, hábitos de vida, polifarmácia, estado de saúde e funcionalidade foram variáveis de controle nos modelos de regressão multinomial. Resultados: Adotando a nota de corte 30/20, encontramos somente a associação entre OA/D e queda única (RRR = 2,37 IC 95% 1,48–3,80). Em contrapartida, adotando a nota de corte 26/16 tanto a OA/D (RRR = 1,93 IC 95% 1,09–3,44), quanto a OA (RRR = 1,65 IC 95% 1,08–2,52) e a dinapenia (RRR = 1,77 IC 95% 1,01–3,13) associaram-se à queda única, sendo o tamanho do efeito da associação maior com OA/D do que com as duas condições isoladas. Além disso, a dinapenia definida com o corte 26/16 associou-se com quedas recorrentes (RRR = 2,39 IC 95% 1,19–4,82). Conclusões: A nota de corte adotada para definir dinapenia modifica as associações de OA, dinapenia, OA/D com queda única e recorrente, sendo o corte 26/16 melhor para identificá-las. / FAPESP: 2015/18291-7

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Monitoring exhaustion using near-infrared spectroscopy (NIRS) wearable biosensors seems promising in sports climbing. However, there is a lack of research regarding climbing specific muscular exhaustion and muscle oxidative metabolism. The current study analyses how exhaustion affects muscle oxidative metabolism and deduces to what extent measurements using NIRS are suitable for an objective monitoring as well as feedback of exhaustion. / Die Überwachung der Erschöpfung mit Hilfe von Nahinfrarotspektroskopie (NIRS) und tragbaren Biosensoren scheint beim Sportklettern vielversprechend. Allerdings fehlt es an Untersuchungen zur kletterspezifischen muskulären Erschöpfung und zum oxidativen Muskelstoffwechsel. Die vorliegende Studie analysiert, wie sich die Erschöpfung auf den oxidativen Stoffwechsel der Muskeln auswirkt, und leitet ab, inwieweit Messungen mit NIRS für eine objektive Überwachung sowie für ein Feedback der Erschöpfung geeignet sind.