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The electrical admittance of myocardium can be used to distinguish between stunned, ischemic and necrotic myocardial tissue. Myocardial stunning is the reversible contractile dysfunction following a brief ischemic episode. This reversible nature is clinically significant and is in contrast to the irreversible myocardial dysfunction that occurs with necrosis. This dissertation aims at developing an instrument to measure myocardial admittance during ischemia and subsequent reperfusion and to study the underlying mechanisms governing the onset and progression of ischemia and stunning. The instrument was tested on Langendorff models of the isolated rat heart that has been subjected to varying durations of global no flow ischemia and subsequent reperfusion. The relative permittivity and conductivity of the myocardium was determined and this could be correlated to the state of the tissue.

Measuring physiological parameters or vital sign using camera has become popular in recent years. Contact-less monitoring and extraction of vital signs can be important source of information in situations like medical care system and safety control system. This paper presents the implementation of real-time, non-contact method for extraction of vital signs, heart rate in this case. A better face tracking method is used for efficient face detection. This study extends some of the previous works done and have a comparison study with several methods. The developed system used filtering with window over the green channel of the signal and then Converted to frequency domain to analyze the signal to detect heart rate. The developed system achieved high correlation and showed small error while referencing with actual heart signal from ECG. This method delivers better result in better light condition but gives fairly good result on lower light as well.

Abstract It has widely been shown that exercise, particularly aerobic exercise, has extensive cardioprotective benefits and is an important tool in the prevention of coronary heart disease (CHD). The present investigation aimed to determine the multivariate impact of strength training, designed to prevent the development of CHD, on the Framingham Risk Assessment (FRA) score. Twenty-eight healthy untrained men with low CHD risk (mean age 28 years and 7 months) participated in an eight-week (3- d/wk) strength training programme. Self-administered smoking records, resting blood pressures, total cholesterol (TC), high-density lipoprotein cholesterol (HDLC), FRA scores and absolute 10-year risks for CHD were determined at the pre-test and post-test. After the eight-week period, no significant (p > 0.05) differences were found in number of cigarettes smoked daily, systolic blood pressure, TC, HDLC, FRA scores and absolute 10-year risks for CHD in both the strength-trained (n = 13) and non-exercising control (n = 15) groups. The data indicate that strength training did not reduce the risk of developing CHD and absolute 10-year risk for CHD as assessed by the FRA score.

published_or_final_version / Medicine / Master / Doctor of Medicine

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Catecholamines have been implicated in the regulation of cardiac hypertrophy. The serial injection of a catecholamine (epinephrine, norepinephrine or isoproterenol) will increase cardiac muscle mass. In a canine model of left ventricular hypertrophy secondary to aortic coarctation, the endogen

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