Mini-dissertation submitted in partial compliance with the requirements for the Master's Degree in Technology: Homoeopathy, Durban University of Technology, 2007. / This study was conducted by administering Chamaeleo dilepis dilepis 30CH to healthy individuals with the aim of eliciting and documenting the resulting mental, emotional and physical symptomology. Chamaeleo dilepis dilepis was chosen as a substance based on it being indigenous to South Africa and as no other members of the Chamaeleonidae species have been proven / M

A dissertation submitted in partial compliance with the requirements for the Master's Degree in Technology: Homoeopathy, Durban University of Technology, 2008. / Conduct a randomised, double blind, placebo controlled study in order to determine the sphere of action of the imponderable remedy Pink 30CH on healthy volunteers who recorded the signs and symptoms produced in order to determine the substances potential usefulness in a future clinical setting according to the Law of Similars. Determine and highlight the commonalities shared between the symptoms and themes produced by remedy Pink 30CH and the other selected imponderable remedies. In the homoeopathic drug proving of remedy Pink 30CH, provers were uninformed to both the nature of the substance as well as to the potency selected and used for proving purposes. Neither the provers nor the research investigator had any knowledge of who received the verum or the placebo until the end of the proving. Thirty (30) provers were selected after meeting the inclusion criteria of which thirty percent (30%) of the subjects received placebo in a randomised fashion. Verum and placebo were dispensed to the proving body in a set of six (6) powders which were taken sublingually three (3) times daily or until any proving symptoms were experienced. All provers were examined and made to record in their journals before, during and after the administration of the proving substance so as to serve as their own intra-individual controls. At the end of the proving period all journals were then recalled and all proving data recorded was then collated and edited into a repertory and materia medica format, which was then used to formulate a homoeopathic drug picture of the remedy that could be used in future clinical settings. The homoeopathic drug picture thus derived was then analysed with the aim of highlighting the important themes that were elicited during the proving. These symptoms and themes were then related and compared to seven (7) other imponderable remedies: Luna (Moonlight); Magnetis Polus Arcticus (North pole of the magnet); Magnetis Polus Australis (South pole of the magnet); Positronium (Anti-matter); Radium bromatum (Radium bromide); Sol (Sunlight) and X-ray, in order to expand the overall understanding of the commonalities shared by the imponderabilia as an entirety. / M

Dissertation submitted in partial compliance with the requirements for the Masters Degree in Technology: Homoeopathy, Durban Institute of Technology, 2002. / The purpose of this study was to analyse and compare the NMR spectra of homoeopathic Sulphur (the most well-known and often tested homoeopathic remedy) in two commonly used potencies, namely the centesimal (CH) and decimal (DH) potencies. Both potencies were prepared according to the Hahnemannian method. In order to assess the differences and similarities between these two potency scales, remedies with the same levels of deconcentration, and remedies with the same numbers of succussions were tested. The Control substance used was Water-Ethanol 87% without lactose or Sulphur. The Control substance was prepared in the same way as the Sulphur i.e. potentised as the Sulphur. Chemical shift and relative integration values of the H20, OH and CH2 peaks were recorded, calculated and compared. The investigation was designed as a scientific experiment. Firstly, the Sulphur remedies were compared to the Controls. Secondly, Sulphur remedies were compared to Sulphur remedies, and Controls to Controls. The following criteria were used: o Equal deconcentrations of the centesimal scale were compared to their equivalent decimal scale. o Equal numbers of succussions of the centesimal scale were compared to their equivalent decimal scale. The following potencies were assessed for both Sulphur and Control (Water-Ethanol): / M

Thesis (M.Tech.: Homoeopathy)-Dept. of Homoeopathy, Durban University of Technology, 2008. xiii, 159 leaves / The purpose of this study was to determine the effects of Gymnura natalensis in the thirtieth centesimal potency on healthy volunteers and to record the signs and symptoms produced by the volunteers during the study. These signs and symptoms determined the therapeutic indications of this remedy for its prescription according to the homoeopathic Law of Similars. A further aim of this study is a proposed group analysis of a natural family of biologically unrelated sea animal remedies (Mangialavori, 2002) with the aim of highlighting themes, similarities and differences within the group.

Thesis (M.Tech.: Homoeopathy)--Durban University of Technology, 2008 / The proving substance Hemachatus haemachatus commonly known as the Rinkhals belongs to the family of Elapidae. This spitting-cobra is a local snake found only in Southern Africa. This proving tested the effects of the thirtieth centesimal (30CH) potency of venom from Hemachatus haemachatus on healthy provers. OBJECTIVES It was hypothesised that Hemachatus haemachatus 30CH would produce clearly observable signs and symptoms in healthy provers, and that the comparison of Hemachatus haemachatus to those yielding the highest numerical value and total number of rubrics on repertorisation of the proving symptoms would highlight differences and similarities between the remedy symptoms so that confusion as to the indication is eliminated. It was hypothesised that a fuller understanding of Hemachatus haemachatus and its relationship to other remedies would be gained following this comparison. METHODOLOGY A double blind, placebo controlled proving of Hemachatus haemachatus 30CH was conducted on thirty healthy volunteers who met the inclusion criteria. Six of these thirty provers randomly received placebo, with neither prover nor researcher knowing whom received placebo. Provers had a homoeopathic case history taken and a physical examination performed on them prior to commencement of the proving. The provers recorded their signs and symptoms 6 by means of a journal before, during and after administration of the remedy. On completion of the proving, the information obtained was correlated and assessed by the two researchers, De la Rouviere and Cahill. The symptoms elicited during the proving were translated into materia medica and repertory language, and a homoeopathic picture of the remedy was subsequently formulated. Data from the case histories, physical examinations and group discussions were also considered in the assessment. RESULTS During the period of investigation, provers experienced a variety of symptoms on the mental, emotional and physical spheres. On the mental emotional sphere there was a marked degree of irritability and changeability in moods as is commonly seen in many of the snake remedies. Along with this, it was noted that there were feelings of anxiety for reasons unknown, a sense of having lost something or someone close, and a desire to be left alone. There were also a great number of feelings regarding the home, where there were feelings of the home being a place of safety and wanting order in the home. On a physical level, many of the provers noted varying degrees of abdominal discomfort and headaches. Along with anxiety, provers experienced palpitations and sensations of chest restriction or constriction with shortness of breath. There were a variety of musculoskeletal symptoms ranging from painful joints in the fingers to stiffness and tightness in the neck and back. Provers noted flushes of heat and alterations of their internal thermostat. Provers experienced marked dryness of the mucus membranes and the skin, and there was also a general feeling of weakness and heaviness as well as a marked aggravation in the mornings on waking. 7 CONCLUSIONS Symptoms obtained from the proving of Hemachatus haemachatus 30CH were studied and evaluated. Those symptoms that appeared to represent the remedy picture of Hemachatus haemachatus most accurately in the researchers‟ opinion were used in the repertorisation of the remedy. The investigation supported the hypothesis that Hemachatus haemachatus 30CH would produce clearly observable signs and symptoms in healthy provers. The subsequent comparison of the proving symptoms of Hemachatus haemachatus to Lycopodium (Club moss), Sulphur, Alumina (Aluminium oxide), Sepia (Cuttle fish) and Calcarea carbonica (Carbonate of Lime) highlighted differences and similarities between these remedies and Hemachatus haemachatus. The further comparison of remedies that came up on repertorisation restricted to the plant, mineral and animal kingdoms respectively provided a further comparison of remedies, which aimed at enhancing the differentiation of Hemachatus haemachatus to other similar remedies.

Mini-dissertation submitted in partial compliance with the requirements of the Master's Degree in Technology: Homoeopathy in the Faculty of Health Sciences at the Durban University of Technology, 2007 / The homoeopathic drug proving of Erythrina lysistemon 30CH took a form of a randomised triple–blind, placebo–controlled study. This trial was conducted at the Homoeopathic Day Clinic on the premises of Durban University of Technology. The research group consisted of 32 provers, which were recruited from amongst practicing homoeopaths, homoeopathic students (2`nd–5`th year), as well as patients of the Homoeopathic Day Clinic (DUT) and their relatives. The participation was purely on voluntary basis. Provers were randomly divided into two groups: a placebo group of 12; a proving group of 20. Each researcher supervised 8 provers. Neither the provers, nor the researchers were aware of the name or nature of the substance being proved, and whether a prover is receiving a placebo or the proving substance until the unblinding process. Provers had a homoeopathic case history taken and a physical examination performed on them before commencement of the proving to establish each individual’s baseline. Provers were required to keep journals in which they recorded their sign and symptoms: starting 7 days prior to commencing the proving, throughout the proving, as well as after administration of the remedy formulated. All the information gathered was then correlated and interpreted by the researchers i.e. four M.Tech.Hom students. Subsequent translation of the symptoms into materia medica and repertory language took place. On completion of the proving a homoeopathic picture of the remedy with III distinct affinities was established. Those affinities were then compared to the toxicology of the major chemical constituents of Erythrina lysistemon. Data was then analyzed by qualitative methods for it was not amendable to standard statistical analysis.

Mini-dissertation submitted in partial compliance with the requirements for the Master’s Degree in Technology: Homoeopathy in the Department of Homoeopathy at the Durban University of Technology, 2008. / The aim of this study was to determine the effect of Gymnura natalensis 30CH on healthy volunteers, and to record the signs and symptoms produced, so that it may be prescribed to those requiring it according to the Law of Similars. The other aims of this study were to compare the proving symptoms of Gymnura natalensis 30CH to the toxicology of stingray venom and to analyze the remedy picture in terms of the Doctrine of Signatures. It was hypothesised that the thirtieth centesimal potency of the remedy would produce clearly observable signs and symptoms in healthy volunteers (provers). It was further hypothesised that the above signs and symptoms would show a correlation to the toxicology of stingray venom and to the Doctrine of Signatures. The homoeopathic proving of Gymnura natalensis took the form a double-blind, randomised, placebo-controlled trial. The selected proving potency was the thirtieth centesimal potency. A total population of 30 suitable and consenting volunteers participated in this trial. Twenty percent of this population was randomly administered a placebo-control substance. The collection of data from the provers took the form of a journal which was kept by each prover in which their proving signs and symptoms were recorded over a period of five weeks after the administration of the remedy or placebo. On completion of the proving, each journal was assessed by the researcher to determine the suitability of the recorded symptoms for inclusion in the materia medica of Gymnura natalensis. These symptoms were then translated into the language of the materia medica and repertory and a remedy picture was then formulated. Data from case histories, physical examinations (Appendix D) and group discussions were also taken into account during the analysis of the proving the symptoms. A concurrent proving study of Gymnura natalensis, conducted by Naidoo (2008), focused on comparing the symptoms of this remedy to those of other existing remedies that were derived from the sea. A variety of mental, emotional and physical symptoms were extracted from the proving study of Gymnura natalensis. The main mental and emotional symptoms of the remedy included anxiety, irritability, depression, a feeling of disconnection, spaciness of the mind and dreams of events and incidents of the past. The characteristic physical symptoms obtained from the proving included headaches, a reduction of pre-menstrual symptoms, heart palpitations, skin eruptions on the back, low energy levels, tiredness and sleep abnormalities. Symptoms that showed a correlation to the toxicological symptoms of stingray envenomation included frequent urination, muscular cramps, heart palpitations, laboured breathing, fever and copious night sweats. The symptoms that characterised the remedy in terms of the Doctrine of Signatures included anxiety, instinctive behaviour, the desire to be alone, feelings of disconnection, detachment and isolation and skin eruptions on the back. The investigation confirmed the hypothesis that Gymnura natalensis would produce clearly observable sings and symptoms in healthy volunteers. The correlation of the proving symptoms to the toxicology of stingray venom and the Doctrine of Signatures provided a clarification of the remedy picture to assist in the understanding and prescription of this remedy.

Dissertation submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, in the Faculty of Health Sciences at the Durban University of Technology, 2008. / The purpose of this double blind placebo-controlled study was to evaluate the efficacy of a homoeopathic complex (Germanium metallicum 30CH, Nux vomica 12CH, Kalium phosphoricum 6CH, Picricum acidum 6CH) in the treatment of job burnout in the human services field. In total 30 participants were chosen according to specific inclusion and exclusion criteria. The sample group was then randomly divided into a treatment group consisting of 15 participants, and a placebo group consisting of 15 participants. The study was conducted at the Durban University of Technology. The Maslach Burnout Inventory – Human Services Survey (Appendix A) was used as a measurement tool. There was an initial consultation with the researcher which consisted of a full consultation, physical examination and administration of the survey. Thereafter there were two follow-up consultations at 4 week intervals at which the survey was re-administered. Medication was dispensed to the participants at the initial and the first follow up consultations only. The data obtained from the Maslach Burnout Inventory – Human Services Survey was statistically analysed using the SPSS software package (Version 15). Due to the small sample size of the study non-parametric tests were conducted. The intra-group analysis was performed using Friedman‟s Test and Wilcoxon‟s Signed Rank Test. The inter-group analysis was performed using the Kruskal-Wallis Test. Friedman‟s Test indicated a significant improvement in the emotional exhaustion subscale for both the treatment and placebo groups. The subscales of depersonalisation and personal accomplishment did not however reflect a significant difference.The Wilcoxon‟s Signed Rank Test indicated that for both groups there was a significant improvement in the emotional exhaustion subscale between baseline and follow up 1 and between follow up 2 and baseline (i.e. P<0.05). The Kruskal-Wallis Test showed no significant difference between the treatment and placebo groups. This was the case for all three subscales of the Maslach Burnout Inventory – Human Services Survey. The results of the study led to the conclusion that statistically the homoeopathic complex (Germanium metallicum 30CH, Nux vomica 12CH, Kalium phosphoricum 6CH, Picricum acidum 6CH) was not effective in the treatment of job burnout.

Submitted in partial compliance with the requirements of the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, Durban, South Africa, 2018. / Background : Excessive daytime sleepiness (EDS) is the inclination or compulsion to fall asleep whilst intending to stay awake; it is believed to negatively affect occupational and social functioning and may be a predisposition towards accidents (Hayley et al. 2014), low productivity and interpersonal problems (Fong et al. 2005). Excessive daytime sleepiness is one of the most common sleep-related symptoms and it affects an estimated 20% of the population (Pagel .2009). The causes of EDS are numerous and include intrinsic sleep disorders (e.g. narcolepsy, obstructive apnoea/ hypopnea syndrome, idiopathic hypersomnia), and extrinsic disorders (Banerjee et al. 2004). Sleep deprivation is probably the most common cause of excessive daytime sleepiness. This clinic trial intended to evaluate the effectiveness of a homoeopathic complex (Nux moschata D6, Phosphoricum acidum D30, Helliborus niger D6, Opium D30) in the management of EDS in terms of the Epworth Sleepiness Scale (Johns, 1991) and Stanford Sleepiness Scale (Hoddes et al. 1973). And this randomised, double-blind placebo controlled study also aimed to provide a safe and effective alternative therapy for EDS. Aim of the study : The objective of this study was to determine the efficacy of a homoeopathic complex (Nux moschata D6, Phosphoricum acidum D30, Helliborus niger D6, Opium D30) and placebo in the management of EDS in terms of the Epworth Sleepiness Scale (ESS) and the Stanford Sleepiness Scale (SSS). Materials and Methodology : A sample group of 35 participants was selected voluntarily to conduct the study on basis of the inclusion and exclusion criteria. The participants were than randomly divided into two groups; a treatment group consisting of 23 participants and a placebo group consisting of 12 participants. Each participant had to attend three consultations in total with the researcher over a period of four weeks at the Durban University of Technology (DUT) Homoeopathic Day Clinic. At the first consultation a comprehensive case history (appendix F) was taken and physical examination (appendix E) was performed by the researcher but no medication was handed at that point. At each consultation the participants with the help of the researcher completed the Epworth Sleepiness Scale (ESS), and the seven days’ baseline Stanford Sleepiness Scale (SSS) was handed to the participants at the first and second consultation which the participants completed without the help of the researcher throughout the trial till their last consultation. Results : Results from the two measuring tools were statistically analysed with SPSS version 24.0. the participant’s level of sleepiness improved in both the treatment group and the placebo group. Intra-group analyses of ESS means revealed that both groups improved significantly over time, intergroup ANOVA analysis however revealed no significant differences between the groups. Section analyses however using the Fisher’s Exact Tests did reveal statistically significant differences within certain variables at some points of the study. Intra-group analyses of SSS data revealed no statistically significant change in SSS scores over the three weeks in both the Homoeopathic Complex and the Placebo Groups, as well as the Inter-group Fischer’s Exact tests revealed no statistically significant differences between the groups. Conclusion : Barring a few exceptions described in Chapter 4 & 5 it can be concluded from the results of the study that statistically the Homoeopathic complex (Nux moschata D6, Phosphoricum acidum D30, Helliborus niger D6, Opium D30) was not superior to placebo in the treatment of EDS. The data shows that both the Homoeopathic Complex and the placebo interventions had a positive effect on EDS and were effective in improving the level of excessive daytime Sleepiness. Irrespective of the general lack of statistical significance between groups a closer analysis of the intragroup and inter-group data does reveal a trend suggesting clinical significance in support of the effectiveness of the homoeopathic complex in the treatment of EDS however this needs to be further explored and confirmed in subsequent studies. / M

Dissertation submitted in partial compliance with the requirements for the Master's Degree in Technology: Homoeopathy, Technikon Natal, 1999. / The purpose of this investigation was to determine the effects of the thirtieth centesimal (30 CH) potency of the venom of Bitis arietans arietans (the Puffadder) on healthy individuals in order to elucidate the totality of morbid symptoms produced by the drug, so that it may be prescribed according to the Law of Similars, as required by homoeopathic science. It was hypothesised that the 30 CH potency of Bitis arietans arietans would produce clearly observable symptoms and signs in healthy volunteers. / M