Introdução e objetivos: A ejaculação precoce é uma forma de disfunção sexual presente em 25,8% dos homens brasileiros. O objetivo do presente estudo é avaliar se a associação de tadalafila, um inibidor da fosfodiesterase-5 e fluoxetina, um inibidor da recaptação da serotonina em uma apresentação de liberação lenta, ambos tomados uma vez por semana, pode prolongar o tempo de latência da ejaculação em homens com ejaculação precoce. Pacientes e Métodos: Sessenta pacientes com ejaculação precoce e sem disfunção erétil foram avaliados. A idade média foi 45,5 anos de idade (desvio padrão +/- 9,6). O tempo médio de ejaculação antes do início do tratamento era 51,3 segundos (desvio padrão +/- 23 segundos) e não foi estatisticamente significativo entre os grupos (p=0,805). Foram distribuídos de forma aleatória e duplo-cega em 4 grupos, conforme a medicação recebida: (1) fluoxetina 90 mg e placebo, (2) tadalafila 20 mg e fluoxetina 90 mg, (3) tadalafila 20 mg e placebo, e (4) placebo com placebo. Antes de iniciar qualquer medicamento, os pacientes anotaram o tempo de latência para ejaculação com um mesmo cronômetro uma vez por semana, durante 3 semanas. À partir do início do uso dos medicamentos, os pacientes cronometraram o tempo em nove ocasiões, uma vez por semana. Foi usado fluoxetina 90 mg ou placebo semanalmente e tadalafila 20 mg ou placebo em um intervalo de até 36 horas da presumida relação sexual com parceira heterossexual regular. Os pacientes foram prospectivamente seguidos a cada 3 semanas durante 12 semanas. Resultados: A comparação dos grupos com análise de variância (ANOVA) unidirecional demonstrou diferença estatisticamente significativa no tempo de ejaculação após tratamento (p<0,001). O maior aumento em relação ao tempo basal foi observado no grupo que associou tadalafila 20 mg com fluoxetina 90 mg semanalmente (p<0,001). Reações adversas foram observadas, tendo sido toleradas e equivalentes entre os grupos usando princípio ativo. Conclusão: Tadalafila 20 mg utilizada em um período de 36 horas de atividade sexual associado com fluoxetina 90 mg de liberação lenta usada semanalmente, significativamente aumentou o tempo de latência de ejaculação em homens com ejaculação precoce, quando comparados com cada droga usada isoladamente, beneficiando esses pacientes sem a necessidade do uso diário de medicamentos. / Introduction and Objectives: Premature ejaculation is a sexual disorder present in 25.8% of brazilian men. The aim of the present study is to evaluate if the association of tadalafil, a phosphodiesterase-5 inhibitor and fluoxetine, a selective serotonin reuptake inhibitor in a slow release presentation, both taken once a week, can prolong the intravaginal ejaculatory latency time (IELT) in men with premature ejaculation. Methods: Sixty patients with premature ejaculation and no erectile dysfunction were enrolled in the protocol. Mean age was 45.5 years (range 24 - 64 years, standard deviation +/- 9.6). They were randomly assigned in a double-blind manner into 4 groups to use the medications: (1) fluoxetine 90 mg and placebo, (2) tadalafil 20 mg and fluoxetine 90 mg, (3) tadalafil 20 mg and placebo, and (4) two different placebo capsules. Before starting any medication, each individual timed the IELT with a given stopwatch in 3 different days, and likewise weekly during the treatment period. Mean IELT before starting treatment was 51.3 seconds (sd: +/- 23 seconds), and was not different between groups (p=0.805). They took fluoxetine 90 mg or placebo once a week, and tadalafil 20 mg or placebo in a 36-hour frame of intended sexual intercourse with a regular heterosexual partner. Patients were prospectively followed every 3 weeks during a 12-week interval. Results: Comparison between groups with oneway ANOVA demonstrated a statistically significant difference in post-treatment IELT (p<0.001). The greatest increase in time from baseline IELT was observed in patients in the tadalafil plus fluoxetine group (p<0.001). Side effects were observed and tolerated, being equivalent in groups using active drugs. Conclusion: Tadalafil 20 mg taken in a 36-hour window for sexual intercourse associated with fluoxetine 90 mg in a slow release form taken weekly, significantly increased the intravaginal ejaculatory latency time from baseline in men with premature ejaculation, when compared to either drug taken solely, benefiting patients without the need to be medicated on a daily basis.

Prenant pour exemple la figure littéraire de l‟employé de bureau, notre étude se propose de saisir les particularités synchroniques et le cheminement diachronique d‟une esthétique de l‟impotence qui aurait notamment émergé avec la tentation flaubertienne du « livre sur rien », pour se développer ensuite dans une large part du roman français de la première moitié du XXe siècle et trouver, enfin, son aboutissement dans l‟oeuvre de Samuel Beckett. La figure du copiste permet en cela de dessiner un paysage littéraire dans lequel s‟inscrivent, à côté d‟écrivains célèbres, de nombreux auteurs oubliés malgré l‟importance qu‟ils eurent en leur temps / This thesis takes the typical character of the office worker as an example to try and show the synchronic particularities and the diachronic development of an aesthetics of impotence. The aesthetics of impotence may have more particularly emerged from the Flaubertian dream of the novel “about nothing” and developed afterward in a large part of the French literature in the first half of C20 to finally find its achievement in Samuel Beckett‟s work. The figure of the office worker allows to sketch a litterary landscape in which one can find many different authors : the most famous alongside the ones who have been long forgotten despite the importance they had in their days

Assignment (MA)--University of Stellenbosch, 2007. / ENGLISH ABSTRACT: This is an explorative literature study of the theoretical relationship between rape and masculinity. It is aimed at understanding how rape can be used by men to construct their gender identity. Its focus is only on this relationship and not the two phenomena in themselves. It approaches the topic from a social constructionist theoretical perspective. I found through my research that men do tend to use rape as a resource to attain a desirable or hegemonic masculinity when other economic or social resources are not available. The picture of a rapist, which emerged, was that of a man who was disempowered either economically or socially. This impotence influences men to seek power through sexual means. / AFRIKAANSE OPSOMMING: Hierdie is ‘n eksploratiewe literatuurstudie oor die verhouding tussen verkragting en manlikheid. Dit poog om te verstaan hoe verkragting deur mans gebruik kan word om hulle geslagsidentiteit te konstrueer. Die fokus van die studie is slegs op hierdie verhouding en nie op die twee fenomene in sigself nie. Dit benader die onderwerp van ‘n sosiaal-konstruksionistiese teoretiese perspektief. Ek het in my navorsing gevind dat mans geneig is om verkragting as ‘n manier te gebruik om ‘n begeerde of hegemoniese manlikheid te bewerkstellig wanneer ander ekonomiese of maatskaplike middele nie beskikbaar is nie. Die beeld van ‘n verkragter wat te voorskyn gekom het, was van ‘n man wat of ekonomies of maatskaplik ontmagtig is. Hierdie ontmagtiging beïnvloed mans om mag deur middel van die seksuele te probeer verkry.

Bakgrund: Det är känt att erektil dysfunktion, eller impotens, orsakas av förstorad prostata, depression och diabetes. Den typ av erektil dysfunktion som orsakas av diabetes har en mer komplicerad utveckling än övriga orsaker.Syfte: Syftet med denna litteraturöversikt var att belysa sexuellt aktiva mäns erfarenheter av erektil dysfunktion till följd av diabetes mellitus typ 2. Metod: Metoden som valdes var en litteraturöversikt med kvalitativa och kvantitativa artiklar. Datamaterialet bestod av tio kvantitativa och två kvalitativa artiklar. Resultat: Två kategorier identifierades såsom Livet påverkas samt Förståelse för situationen med underkategorier. Konklusion: Det råder kunskapsbrist i fråga om varför män drabbas av erektil dysfunktion. Många män anser inte att det finns någon fungerande behandling. Om kontroll av den erektila funktionen ingick i årskontrollen av diabetes tillsammans med en välgrundad information samt adekvat behandling skulle de drabbade männen och deras partner få bättre insikt och medvetande om problemet. Detta skulle leda till mindre oro, bättre sexuell och mental hälsa samt en bättre relation. / Background: It is commonly known that erectile dysfunction, popularly known as impotence, is caused by several factors including enlarged prostate, depression and diabetes. The erectile dysfunction caused by diabetes has a more difficult progress than other causes.Aim: The aim of this study was to illustrate sexually active men’s experiences of erectile dysfunction caused by diabetes mellitus type 2. Method: The chosen method was a literature review based of qualitative and quantitative articles. Ten quantitative and two qualitative articles were analysed. Results: Two categories were identified, Affects on life and Understanding the situation with subcategories. Conclusions: There is lack of knowledge about why men suffer from erectile dysfunction. Several of the men do not believe there is a treatment for their problem. If erection status was a part of the annual diabetes check-ups as well as valid information and adequate treatment the men and their partner would have better knowledge and awareness about the condition. This would also result in less anxiety, better sexual and mental health and a better relation.

The aims of this study were to determine the effects of smoking on the incidence and prognosis of erectile dysfunction (ED) and that of ED on smoking behavior, and to find out whether smoking either directly or through vascular diseases causes ED. The target population comprised of all men born in 1924, 1934 or 1944 and residing in the city of Tampere or 11 adjacent municipalities in Finland. Questionnaires were mailed to 3,143 men in 1994, to 2,864 in 1999 and to 2,510 men in 2004. The response rates were 70%, 75% and 75% respectively. ED was assessed using two questions on subjects’ erectile capacity. Logistic and Poisson regression models were used in the multivariable analyses. Current smoking was associated with ED (Adjusted prevalence odds ratio (POR) = 1.7, 95% CI 1.2-2.4), but not with ex smoking. The incidence of ED non-significantly increased (incidence density ratio (IDR)=1.4) and that of ED recovery reduced (IDR=0.7) with current smoking. A dose-response relationship was found between smoking and ED. Although the relative risks estimates were not statistically significant, probably due to small numbers. Only heavy smokers were significantly at higher risk of ED. Compared with non-smokers, confounder-adjusted IDR was 1.6 (95% CI 1.0-2.6) for men who smoked 21 cigarettes or more daily. Both quitting (IDR=1.7) and starting smoking (IDR=1.9) were rare and higher in men with ED. However, the IDRs estimates were not statistically significant. Current smokers at baseline (1994) who developed vascular disease during 1994-1999 were three times (Confounder-adjusted IDR=3.1, 95% CI 1.3-7.5) at higher risk of ED during 1999-2004 compared with never or ex smokers who did not develop vascular diseases. On the other hand, current smokers who did not develop vascular diseases were not at higher risk of ED (IDR=1.0). There were two bi-directional relations between smoking and ED. Smoking caused ED though vascular diseases and ED caused smoking. The recovery from ED was less in smokers than in non-smokers, and current smokers with ED were more likely to stop smoking compared with men free from ED. / <p>ISBN 91-7997-124-5</p>

Enhanced external counterpulsation (EECP) is a noninvasive treatment modality which can increase arterial blood flow in peripheral and coronary arterial disease. Several studies have demonstrated an increase in the flow of the internal iliacal artery and in carotid and renal perfusion during EECP treatment. We investigated the effect of EECP in patients with erectile dysfunction (ED). Thirteen patients were treated with EECP for 20 days, 1 h per day. Patients reported a significant improvement of penile rigidity after completion of the EECP treatment and a significant improvement of penile peak systolic flow was measured by Doppler sonography. No adverse effects were observed. In conclusion, EECP seems to be an effective treatment modality in patients with ED. / Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.

Tez (Tıpta Uzmanlık) - Süleyman Demirel Üniversitesi, Tıp Fakültesi, Üroloji Anabilim Dalı, 2006. / Bibliyografya var.

Tez (Tıpta Uzmanlık) - Süleyman Demirel Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, 2006. / Kaynakça var.

Thesis--Catholic University of America. / Vita. Bibliography: p. 169-179.

Thesis--Catholic University of America. / Vita. Bibliography: p. 169-179.