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Rezension zu Julia Dombrowski: Die Suche nach der Liebe im Netz. Eine Ethnographie des Online-Datings. Bielefeld: Transcript 2011

Background Pulmonary diseases are the leading causes of mortality globally amongst children under five years of age. Economic evaluations (EEs) guide decision-makers on which health care intervention to adopt to reduce paediatric pulmonary disease burden. Methods We systematically reviewed EEs for paediatric pulmonary diseases published globally between 2010 and 2020. We searched PubMed, Web of Science, MEDLINE, Paediatric Economic Database Evaluation (PEDE), and the Cochrane library. EEs included were specific to paediatric pulmonary diseases in a hospital setting and of children aged from zero to six years old. We extracted data items guided by the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist. We collected qualitative and quantitative data which we analysed in Microsoft Excel and R Software. Results 22 studies met the inclusion criteria. Seven of the articles were cost-effectiveness analyses, five cost-utility analyses, two cost-minimisation analyses, and eight cost analyses. Fourteen studies were conducted in high-income countries, eight in low-middle-income countries (LMICs). Ten studies were on asthma, nine on pneumonia, two on asthma and pneumonia, and one on tuberculosis. Quality assessment of the articles revealed some methodological inconsistencies across the articles. Conclusion Fewer EEs were conducted in LMICs, yet children from these countries are disproportionately affected by pulmonary diseases. Developing standardised methods for EEs and conducting more EEs and for paediatric pulmonary diseases in LMICs could allow for more evidence-based decision-making.

This article contributes to dialog in the field about the nature of the manuscript review process. It develops a psychoanalytic framework for understanding how participants in the review process construct each other as subjects in discourse and why the experience of alienation inevitably marks this process. The framework suggests that participants can draw on different subject positions with regard to this alienation. One is imaginary and entails the failed fantasy that lack and alienation can be overcome. The other is symbolic and entails a mutual engagement with this failure. The article suggests imaginary positions are less constructive, resulting in struggles between participants as others. By contrast, it suggests symbolic positions are more constructive, resulting in struggles with otherness and opportunities for more creative outcomes. The article explores reviewer reflexivity as an important element of symbolic interactions in which participants have responsibility for the production of relationships in the review process.

Actinomycotic infections involving the oesophagus are uncommon but have been reported in both immunocompromised and immunocompetent individuals. We report a case of actinomycosis oesophagitis in a patient with lung cancer who received chemo- and radiotherapy. This patient was admitted with severe dysphagia and odynophagia and biopsy from an oesophageal ulcer found on oesophagogastroduodenoscopy (EGD) revealed actinomycosis. The patient was treated with intravenous penicillin G followed by ceftriaxone with clinical improvement and repeat EGD showed reduction in the size of the oesophageal ulcer, but he relapsed due to non-compliance. We review the English literature regarding the clinical features, diagnosis, and management of actinomycotic infections of the oesophagus.

Hepatitis C virus (HCV) infection is a chronic blood-borne disease that affects > 4,000,000 individuals in the United States. The majority of individuals with HVC infection acquire a chronic hepatitis that predisposes them to the complications of cirrhosis and hepatoma. Chronic HCV infection is, however, associated with multiple extrahepatic manifestations as well, including recently recognized effects on the lung. These include primary effects on lung function, as well as secondary effects in the settings of progressive liver disease and drug treatment for HCV. In this article, we discuss the emerging clinical data that support a role for HCV infection in lung disease, describe the multiple pulmonary manifestations of this viral infection, and outline the therapies available for specific pulmonary complications of chronic HCV infection.

BACKGROUND: Hypoalbuminemia (HA) is common in HF, however, its pathophysiology and clinical implications are poorly understood. While multiple studies have been published in the past decade investigating the role of serum albumin in HF, there is still no consensus on the prognostic value of this widely available measure. The objective of this study is to assess the prognostic role of albumin in heart failure (HF) patient. METHODS: Unrestricted searches of MEDLINE, EMBASE, Cochrane databases were performed. The results were screened for relevance and eligibility criteria. Relevant data were extracted and analyzed using Comprehensive Meta-Analysis software. The Begg and Mazumdar rank correlation test was utilized to evaluate for publication bias. RESULTS: A total of 48 studies examining 44,048 patients with HF were analyzed. HA was found in 32% (95% confidence interval [CI] 28.4%-37.4%) HF patients with marked heterogeneity (I2 = 98%). In 10 studies evaluating acute HF, in-hospital mortality was almost 4 times more likely in HA with an odds ratios (OR) of 3.77 (95% CI 1.96-7.23). HA was also associated with a significant increase in long-term mortality (OR: 1.5; 95% CI: 1.36-1.64) especially at 1-year post-discharge (OR: 2.44; 95% CI: 2.05-2.91; I2 = 11%). Pooled area under the curve (AUC 0.73; 95% CI 0.67-0.78) was comparable to serum brain natriuretic peptide (BNP) in predicting mortality in HF patients. CONCLUSION: Our results suggest that HA is associated with significantly higher in-hospital mortality as well as long-term mortality with a predictive accuracy comparable to that reported for serum BNP. These findings suggest that serum albumin may be useful in determining high-risk patients.

The editors of Authors Take Sides on the Spanish War, which was published in London by the Left Review in 1937, posed two questions to a list of writers: "Are you for, or against, the legal Government and the People of Republican Spain? Are you for, or against, Franco and Fascism?" The question was distributed by mail to hundreds of writers in the United Kingdom to solicit responses for publication. The editors' appeal closes: "We wish the world to know what you, writers and poets, who are amongst the most sensitive instruments of a nation, feel." Authors Take Sides on the Spanish War consists of brief remarks from 148 contributors in a "10,000 word" pamphlet. Authors Take Sides on the Spanish War contains many influential writers' opinions on one of the most significant conflicts of the twentieth century, but the publication has since received almost no editorial attention. The pamphlet was reissued in 2001 as a photoduplication of the original--without commentary or annotation--and due to a printer's error, it is missing two leaves. This annotated edition of Authors Take Sides on the Spanish War includes an archive of related correspondence, articles, and other writings pertinent to the pamphlet and the political, social, and cultural climate of Europe around the Spanish Civil War. Of particular interest are unpublished documents related to the publication of the pamphlet from the Nancy Cunard archive at the University of Texas-Austin's Harry Ransom Center for the Humanities, as well as an examination of textual decisions and revisions within the work of Arthur Koestler and six other authors who wrote on the Spanish Civil War. It is in this way that this edition of Authors Take Sides on the Spanish War also takes on many of the qualities of a dossier in that it brings together documentary evidence of a certain kind to provide a range of perspectives on this cultural and historical moment. / 2016-11-01T00:00:00Z