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1 / Fading Chen

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Errata inserted. / Includes bibliographical references. / xi, 119, [75] leaves, [21] leaves of plates : ill. (chiefly col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / This study demonstrates a conserved structural organisation of the mouse LIF gene that produces three differentially localised proteins. This provides a mechanism for specific control of the sites of LIF action and mechanisms for mediating the variety of putative actions for the LIF gene. Intracellular localisation of the LIF protein provides another example of intracellular cytokine action, mediated by a novel mechanism and provides a system for separate analysis of intracellular and extracellular cytokines. / Thesis (Ph.D.)--University of Adelaide, Dept. of Biochemistry,1998?

Errata inserted. / Includes bibliographical references. / xi, 119, [75] leaves, [21] leaves of plates : ill. (chiefly col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / This study demonstrates a conserved structural organisation of the mouse LIF gene that produces three differentially localised proteins. This provides a mechanism for specific control of the sites of LIF action and mechanisms for mediating the variety of putative actions for the LIF gene. Intracellular localisation of the LIF protein provides another example of intracellular cytokine action, mediated by a novel mechanism and provides a system for separate analysis of intracellular and extracellular cytokines. / Thesis (Ph.D.)--University of Adelaide, Dept. of Biochemistry,1998?

Thesis (Ph. D.)--University of Adelaide, Dept. of Biochemistry, 1998? / Errata inserted. Includes bibliographical references.

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Subject of diploma thesis is assessment of influence addition inhibitors in liquid urea–ammonium nitrate (UAN) fertilizer on the yield and oiliness of rape. The experiment was solved in two-years (2017, 2018) form small-field experiment in research station Žabčice. In experiment was included four variants of fertilization: 1. ANCS (ammonium nitrate with calcium sulfate) + UAN (urea ammonium nitrate), 2. ANCS +UAN + IN (nitrification inhibitor), 3. ANCS + UAN + IU (urease inhibitor), 4. ANCS + UAN + IN + IU. Addition of inhibitors in liquid fertilizer UAN didn't has statically conclusive effect on rape seed yield. The highest yield was achieved in variant ANCS + UAN with yield of 4,1 t/ha. The lowest yield was achieved in variant ANCS + UAN + IN with yield 3,9 t/ha. Weather was above average warm and dry in both reference years. The efficiency of nitrification inhibitors with rising temperature decreases linearly. The found oiliness of rape seeds from individual fertilization variants was relatively balanced. The applied inhibitors didn't significantly affect the oil content in the seeds. The highest oiliness was achieved in variant ANCS + DAM with oiliness of 40,7 %. The lowest oiliness was achieved in variant ANCS + UAN + IN + IU with oiliness of 40,4 %.

Lateral inhibitory networks (LINs) of neurons are thought to be prominent in sensory systems and are known to enhance spatial edges and peaks in their input excitation patterns. It is postulated, based on experimental findings, that lateral inhibition contributes to central, sub-cortical, auditory processing. Previous computational LIN models of the central processing of auditory nerve activity were based on highly simplified, non-spiking models of neurons. A more biologically realistic LIN model of spiking neurons was thus developed to investigate the plausibility of such networks achieving contrast enhancement and speech feature extraction. The model developed is a single-layer, uniform, recurrent LIN structure. Each neuron in the LIN is described by a leaky integrate-and-fire model with conductance-based synaptic input. Input spike instances were obtained from Bruce and colleagues' [2003] model of the auditory periphery for synthesized speech stimuli or from a Bernoulli approximation of a Poisson process to represent spontaneous activity from the auditory nerve. The effect of neural and network parameters on contrast enhancement exhibited in the mean spike rates was measured. It was found that the spiking LIN is able to achieve contrast enhancement if the values of the neuronal parameters fall within a very specific and narrow range. Furthermore, the spatial edge in the input had to be high and steep. Compared to non-spiking neuron models, it is quite difficult for spiking neurons to achieve contrast enhancement. The spiking LIN was found to be capable of making formant frequencies more distinct in the average rate profiles of speech stimuli presented at high intensities. However, synchrony of the neural activity to the formant frequencies was largely lost. This architecture of spiking neurons is therefore unlikely to be how contrast enhancement and speech feature extraction is realized in the central auditory system. / Thesis / Master of Applied Science (MASc)

published_or_final_version / abstract / Surgery / Doctoral / Doctor of Philosophy