The purpose of this study was to explore aboriginal perspectives of diabetes, nutrition and health so as to eventually develop culturally-appropriate means of implementing diabetes prevention and intervention activities. The participants included community members living in an Eastern James Bay Cree community in northern Quebec. In this qualitative research study, in-depth interviews, focus groups, and participant observation were used for data collection. Key themes that emerged from analyzing the in-depth interviews were "re-presented" using "found poetry" so as to capture the participants' experiences and perspectives using their own words. Focus groups were carried out to share the initial findings from the in-depth interviews as well as to elicit additional feedback from the community.

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The Hudson-James Bay Lowlands (HJBL) are composed of fens and bogs frequently intersected by rivers and punctured by bioherms (ancient reef mounds) rising from bedrock aquifer. The peatlands exist partly due to minimal vertical losses limited by the low hydraulic conductivity (K) of the Tyrrell Sea sediments and small vertical gradients between the surface and bedrock aquifers. The recent development of an open-pit mine; DeBeers Victor Diamond Mine within the HJBL requires dewatering of the regional limestone aquifer to a depth of 200 mbgs. Two major components in assessing the potential impacts of dewatering on the hydrogeological regime and the sensitive peatland ecosystem are: the characteristics and behaviour of the Tyrrell Sea aquitard, and bioherms as potential recharge enhancing features. The Victor Tyrrell Sea (VTS) deposits are clayey silt with low LL, low PI, and no smectite clay minerals. The clay fraction consists of quartz, illite, chlinochlore, and usually calcite. The deposits are normally consolidated with Cc values of 0.08-0.155 and void ratios of 0.52-0.77. The VTS deposits are grey with pockets of black graphite and frequent shells. The K rages from 6.6x10-9 to 4.7x10-8 m/s. GEO-SLOPE™ finite element modeling software was used to investigate the sensitivity of surface drainage and consolidation behaviour in regard to the range of measured VTS parameters. The behaviours were also compared to classic clay aquitard types such as Lake Agassiz and Lake Champlain. Unit thickness, K, and the K modifier function have the greatest impact on the rate and magnitude of consolidation, and vertical drainage of the surface. The K of the underlying till is extremely important because they can be a buffer between the dewatered bedrock aquifer and the VTS. The characteristics of the sediments and the flow regime surrounding three outcropping bioherms which increase vertical drainage are investigated and a conceptual model of flow is proposed. The sediments in profile around bioherms have different levels of stratification but always contain silt and sand units. The hydraulic conditions at eight nested piezometers and the stratigraphy as defined by a series of auger hole profiles was considered to develop a conceptual model. The flow regime presented is of radial flow towards the bioherms enhanced by high K sediments between the peat and bedrock becoming vertical flow when the high K sediments contact vertical channels in the rock. / Thesis (Master, Geological Sciences & Geological Engineering) -- Queen's University, 2013-02-06 14:47:13.582

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The genetic structuring of populations can be influenced by present processes and past events. One of the largest historical events to affect the distribution and genetic characteristics of present-day North American biota is the Pleistocene glaciation. Thus, the study of post-glacial colonization patterns of species in northern landscapes can relay important ecological information, as species had to expand their range extensively following the retreat of the glaciers and are often at the terminal end of their expansion. These species consequently exhibit the genetic fingerprints of sequential founder events, in turn decreasing the genetic variation available for adaptation. Using amphibians to investigate post-glacial range expansion is advantageous, as they have limited dispersal abilities revealing fine-scale patterns and they are thought to be one of the first vertebrates to colonize post-glacial habitat. Therefore, to model the phylogeography of a primary colonizer and the population structure of anurans in northern landscapes, population genetics analyses of wood frogs (Lithobates sylvaticus) were performed in the James Bay area. Wood frogs were sampled from 17 localities around James Bay and genetic analyses were conducted with seven microsatellite loci and mitochondrial DNA sequences of the ND2/tRNATRP genes. Results show that the post-glacial recolonization of the James Bay area by wood frogs originated from the putative refugium in western Wisconsin, an area known as the Driftless Area. Two routes were taken by founders to colonize the James Bay area: one north-west of Lake Superior, colonizing western Ontario, and one through the Upper Peninsula of Michigan, colonizing southern and eastern Ontario and western Québec. Interestingly, the meeting of the two lineages south-west of James Bay led to the establishment of a zone of higher genetic variation than expected under the founder effect hypothesis. Additionally, population structure analyses revealed the segregation of three genetic populations east, north-west, and south-west of the bay, the latter showing the highest genetic variation and likely representing a zone of secondary contact. This study shows that past events such as post-glacial range expansions can explain present patterns of genetic variation and population structure, and that studies in northern landscapes may be very useful in understanding genetic patterns throughout the range of a species.

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A sustainable primary prevention strategy for infant iron deficiency anemia (IDA) was implemented and evaluated in a community with at-risk infants in northern Quebec, Canada. Communication strategies were used to promote iron-rich complementary food rather than iron-fortified formula, which can interfere with breastfeeding practice. This food-based approach has been successfully implemented in developing countries, but has not been applied in an industrialized country setting. / Mass media (i.e., radio dialogues, key messages, print material, point-of-purchase grocery store display) and interpersonal (i.e., homemade baby food cooking activity) communication strategies were developed in collaboration with community members and implemented in partnership with an existing community program. Reach and exposure of the strategies were measured using a questionnaire administered to a post-intervention sample (n = 45). Sales of promoted iron-rich infant food were examined pre- and post-intervention period. A repeat cross-sectional design was used for the impact evaluation. Two groups of mothers with infants, aged 7-10 months at Time 1 (n = 32) and Time 2 (n = 22) were interviewed. Outcome variables were infants' total iron and complementary food iron intakes measured by two 24-hour recalls. Secular trends in infants' hemoglobin values and milk type consumption were examined in the study community and two comparison communities. / Multiple communication channels increased awareness of IDA and influenced self-reported use of iron-rich infant food. Iron-rich infant food sales increased from pre- to post-intervention (p < 0.05). Complementary food intake iron increased between Time 1 (3.2 +/- 0.8 mg) and Time 2 (4.4 +/- 1.1 mg) (p < 0.05). The proportion of infants with anemia (hemoglobin < 110 g/L) significantly decreased from the period before (37.2%) to during (14.3%) the intervention (p < 0.05). No significant difference was found for this variable within the comparison communities. The proportion of infants receiving iron-fortified formula in the study community did not differ between Time 1 and Time 2, but increased from Time 1 (55%) to Time 2 (73%) (p < 0.05) in the comparison communities, indicating an erosion of breastfeeding practice. / These results suggest the effectiveness of communication strategies to improve infant iron nutrition in a community with good access to iron-rich infant food. The potential for this strategy in other communities warrants further investigation.

Gestational diabetes mellitus (GDM) and infant macrosomia are important obstetric health concerns for Aboriginal populations in Canada. Previous research in non-Aboriginal populations has established that GDM and macrosomia are associated with increased risk of fetal morbidity. Specifically, GDM is a risk factor for infant macrosomia, hypoglycemia, polycythemia, hypocalcemia, and hyperbilirubinemia. Furthermore, macrosomia is an independent risk factor for shoulder dystocia, clavicular fracture, brachial plexus injury, birth asphyxia and operative delivery. The main objectives of this study were to determine prevalence rates of GDM and macrosomia related neonatal complications for the James Bay Cree population of northern Quebec, and to identify risk factors for specific birth trauma injuries and metabolic complications in the population. The prevalence of macrosomia (≥4500 g) was 10.4%, and the estimated prevalence of GDM was 16.6% (95% CI 14.6-18.6) (n = 229/1379). Shoulder dystocia was the most common birth trauma event among the Cree, affecting 2.5% (n = 42/1650) of all Cree births, and 9.3% (n = 16/172) of macrosomic deliveries ≥4500 g. The prevalence of neonatal hypoglycemia was also high, affecting 8.8% (n = 144/1650) of all Cree newborns, and 18.1% (n = 34/192) of GDM deliveries. Macrosomia (BW ≥ 4500 g) was a significant risk factor for shoulder dystocia, clavicular fracture, hypoglycemia, and caesarean section delivery. After adjusting for maternal age, parity, and gestational age, GDM was identified as a significant risk factor for macrosomia (≥4500 g), hypoglycemia, polycythemia, and hypocalcemia. In summary, this study identified a high incidence of neonatal complications among the James Bay Cree compared with rates in the general North American population. These outcomes can be explained, in part, by high prevalence rates of gestational diabetes and infant macrosomia. Further studies to investigate the long-term consequences of GDM and

The objectives of this research were to determine the prevalence of anemia, and identify risk factors for anemia, in 9-month-old Cree infants living in northern Quebec. The prevalence of anemia (hemoglobin <110 g/L) was 25--32%, depending on the study sample. Iron deficiency was present in 28.2% of infants who could be classified and 14.4% had iron deficiency anemia. Fewer than 2% of infants had low birth weight (<2500 g) so most infants should have been born with adequate iron stores. One cause of anemia that was identified was a diet that was low in iron. Only 15.1% of infants were reported by guardians to eat meat daily and 28.5% were reported to never eat meat. Infants who were breastfed or cow's milk fed did not obtain sufficient iron for effective erythropoiesis. Compared with formula that was predominantly iron fortified, the odds ratio (OR) for anemia was 7.9 (95% CI 3.4--18.2) for breast milk and 5.0 (95% CI 2.0--12.7) for cow's milk. When milk type was controlled for, weight gain since birth was significantly associated with microcytic erythrocytes (OR comparing the highest tertile of weight gain to the lowest tertile 2.9, 95% CI 1.2--6.6). This indicates that fast-growing infants were not meeting their iron needs for growth. Another risk factor for anemia that was identified was common childhood infections. The prevalence of anemia among infants reported as recently unwell with an infection was higher than among infants reported as recently well (31.1% vs. 19.0%, chi2 = 4.27, p = 0.039). The prevalence of elevated blood lead was 2.7% and is not a major public health problem. No evidence for vitamin A deficiency was found. Serum retinol was positively associated with all iron status indicators. Cree infants who were given supplements containing vitamin A had a lower prevalence of anemia (hemoglobin <105 g/L) (10.8% vs 23.2%, chi2 = 5.97, p = 0.015). These results suggest a role for vitamin A in iron metabolism. To prevent anemia in aboriginal i

The Lac Guyer greenstone belt in the James Bay region of New Quebec was a zone of active volcanism in Archean times and constituted part of a system of "rifts" known as the La Grande superbelt. The rifting of continental crust initiated with the deposition of a sequence of volcanics dominated by pillowed basalts. An overlying volcanic sequence began with the deposition of rhyodacites and other felsic volcaniclastics, intercalated with mafic flows and tuffs. These, in turn, are overlain by peridotitic and pillowed pyroxenitic komatiite flows and then by pillowed basalts. The rocks in this Archean belt have experienced at least two periods of deformation and attained amphibolite facies. / The early voluminous basalts of the first sequence probably reflect the eruption of steady state liquids from periodically replenished, periodically tapped, magma chambers located near the interface of an early crust and Archean mantle. With time the mafic crust overlying these magma chambers, melted to produce tonalitic-granodioritic magmas. These magmas rose and experienced amphibole fractionation. Residual liquids produced by this fractionation erupted as rhyodacites contemporanously with later basalts. The eruption of komatiitic liquids indicates a major failure of the crustal screen enabling primitive magmas to reach the surface. The spectrum of primitive komatiitic compositions reflects variable degrees (15 to 40%) of partial melting of a garnet lherzolite in the Archean mantle. Pyroxenitic komatiite magmas represent the least degree of melting with garnet remaining in the mantle residue. Garnet was completely consumed, however, in the more extensive melting involved in the production of the peridotitic komatiite magmas. As the volcanic pile of the second volcanic sequence grew crustal magma reservoirs were re-established. Primitive komatiitic magmas held in these reservoirs underwent extensive crystal fractionation to yield residual steady state liquids which erupted as the upper basalts of the second volcanic sequence.