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The National Gallery in Prague conserves an important masterpiece of the Fle- mish mannerist Jan Gossaert. The panel painting Saint Luke painting the Virgin was originally determined for the cathedral of Saint Roumboult in Mechelen in Belgium. The artwork represents one of the first applications of Renaissance style behind the Alps. Gossaert was educated in this new style during a visit to Italy several years earlier and combined it with traditional Flemish art. The artist worked for the court of Margaret of Austria in Mechelen around the year 1513, the year the painting originates. His traditional style became influenced by the techniques used in Mechelen by foreign artists. The theme is painted the tradi- tional manner of work on an oak panel. Renaissance and Gothic architecture is decorated by " en grisaille" sculptures. A seemingly simple theme is given deeper meaning thanks to these objects containing hidden meanings. There are also some prints from the time the panel was in the Saint Vitus Cathedral in Prague due to which we can contemplate the progress in presentation of the painting during centuries. 1