Treatment of pancreatic cancer is an important medical problem. Most pancreatic cancer patients are diagnosed with advanced disease and their prognosis is poor. In Lithuania there were 440 new cases in year 2004. More than fifty percent of patients are diagnosed with stage IV disease [Kurtinaitis J et al., 2005]. Median survival of patients diagnosed with pancreatic cancer, depending on a stage of a disease, spread of the tumor, treatment method, functional status of a patient is from 6 to 20 months. Five-year survival is only 0–5 percent [Bramhall S et al., 1998; Oya N, 2004]. Today, pancreatic cancer is treated by combined methods: surgery combined with RT and/or chemotherapy. It is questionable if a patient diagnosed with pancreatic cancer in early stages must be treated by adjuvant treatment methods, or should patients diagnosed with unresectable cancer be treated with chemotherapy or ChRT; and what is more important for the patient: increased survival or better quality of life. Kaunas University of Medicine Clinic (KMUC) is a suitable hospital to treat patients diagnosed with pancreatic cancer. At the Clinic of Surgery pancreatic cancer patients are treated by radical and palliative surgery; and at the Clinic of Oncology patients with pancreatic cancer are treated applying contemporary methods of RT, chemotherapy and combined treatment methods. In this thesis treatment results of patients treated for resectable and unresectable pancreatic cancer from year 1987 to year... [to full text]