Background: The use of concentrated potassium may result in medication errors or, in worst case scenario, death. Sweden currently does not have any national best practices associated with the use of concentrated potassium, but the Region of Jönköping County (RJL) has initiated the development.  Aim: The study’s aim is to map the usage of concentrated potassium in RJL, compare their usage with the Region of Östergötland’s and find potential improvements compared to an international best practice.  Methods: A cross-sectional study divided into a register study and a scoping review of current literature regarding guidelines on the usage of concentrated potassium.  Results: The product purchased most often was Potassium Chloride (1 mmol/ml) (152 packages/year ± 5,36 in 2018-2021). Operation and intensive care unit bought concentrated potassium with highest frequency (24,3 packages/month ± 11,7 in 2009-2012), and the surgeon clinic prescribed concentrated potassium most often (256 prescriptions in 2021). RJLs’ templates include both potassium-chloride and -phosphate infusions, containing sodium chloride (0,9 mg/ml), glucose (50 – 100 mg/ml) or ringer acetate. None had a total volume < 1000 ml. The Region of Östergötland consistently used more mmol/care places of concentrated potassium than RJL during 2018-2021. Fourteen documents were collected containing 166 guidelines, which were divided into storage (15 guidelines), readily mixed infusions (15 guidelines), dosages (54 guidelines), safety (37 guidelines) and monitoring (19 guidelines).  Conclusion: This study shines a light on different factors related to safe storage and usage of concentrated potassium, as well as the need for regional and national guidelines.