Thesis (Ph. D.)--University of Wisconsin--Madison, 1969. / Typescript. Vita. Description based on print version record. Includes bibliographical references (leaves 237-254).

The adverse effects of malnutrition on the child are diverse and complex. This thesis describes an examination of the effects of severe malnutrition on immune defence mechanisms and in particular on cellular immune function in vitro.

Doctorat en sciences médicales / info:eu-repo/semantics/nonPublished

Thesis (Honors)--College of William and Mary, 2009. / Includes bibliographical references (leaves 98-106). Also available via the World Wide Web.

In South Africa, as: in other countries with a large underprivileged population group, the problem of malnutrition and its- associations and complications assumes considerable importance. Until the socioeconomic problems involved are solved, attention must be directed to early diagnosis, treatment and prophylaxis of malnutrition and its associations. At the Red Cross Children's Hospital, Cape Town, a considerable percentage of admissions are for marasmus and kwashiorkor. Anemia is a frequent association, (Walt, I.959) sometimes contributing to the mortality (Walt, Holman and Naidoo, 1957).

Proefschrift--Amsterdam--Universiteit van Amsterdam, 1989.

A dissertation submitted to the Faculty of medicine of the university of Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Masters of science Johannesburg 1991 / Carnitine plays a role in the transport of activated long chain fatty acyl groups from the site of activation to the site of beta-oxidation in the mitochondria. Endogenous synthesis of carnitine from the amino acids methionine and lysine, takes place mainly in the liver. From there free and acyl carnitine are released into the blood and transported to other tissues.A few studies have indicated that poor nutritional status may lead to carnitine deficiency.[Abbreviated Abstract. Open document to view full version] / GR2017

The diploma thesis deals with children´s malnutrition in Peruvian department of San Martín. The issue is related to children´s health condition as well as to diseases linked with deficiency of nutrients, which can have impact on their physical and mental development. The aim of the thesis is to evaluate the effectivity of the project conducted in the native communities of Chirikyacu and Aviación during the period of ten months between May 2015 and March 2016. Theoretic part of this thesis is aimed at technical aspects of malnutrition and nutrition as well as at health support programs in Peru, which are established in order to improve the local situation. The goal of the thesis was achieved by conducting a local survey research focused on nutrition and feeding habits in the community. Value of effect is measured by the comparison of feeding habits before the educational program and after its termination. The project was aimed at educating mothers in the field of children´s care such as hygienic habits, proper nutrition and sufficient standard of aliments so that the correct development of child is not threatened. Results of the investigation have shown that on the base of the realized project the majority of mothers have changed their previous way of thinking about products suitable for health of the family.

Depuis plusieurs années, il s’avère de plus en plus clair que le microbiote digestif a un impact remarquable sur la santé humaine. Il est affecté par de nombreux facteurs dont l’alimentation. En effet, en fonction du macronutriment majoritaire d’un régime alimentaire, certaines populations et fonctions bactériennes sont stimulées ou inhibées. Plusieurs pathologies de l’intestin ou liées à des troubles nutritionnels ou métaboliques ont un lien causal avec une altération du microbiote digestif parmi lesquelles la malnutrition sévère aigue. En effet, il a été récemment montré que le microbiote digestif des enfants malnutris était différent et colonisé par des Proteobacteria, des Enterococci, des bacilles Gram-négatifs et des espèces pathogènes. Au cours de nos travaux, une dysbiose est également observée chez nos patients malnutris par métagénomique et par culturomics avec un enrichissement en bactéries aérobies, en Proteobacteria et en espèces potentiellement pathogènes telles que Streptococcus gallolyticus et une perte notable en bactéries anaérobies associée à une perte de la capacité antioxydante du tractus gastro-intestinal révélée par une absence totale de Methanobrevibacter smitii, archeae méthanogène et un des procaryotes les plus sensibles à l’oxygène du tractus gastro-intestinal ainsi que un potentiel redox fécal accru. De plus, une perte de la diversité globale, connue et inconnue, est observée. Enfin, par culturomics et métagénomique, nous avons établi un répertoire des bactéries manquantes chez les malnutris dont treize présentent un potentiel probiotique et pourront être testées comme probiotiques dans un modèle expérimental dans un futur proche. / For the last decade, it has become increasingly clear that the gut microbiota has a tremendous impact on human health. It is affected by several factors among which diet that has a big impact. In fact, according to the major macronutrient in a diet type, specific bacterial populations and functions are stimulated or inhibited. Several pathologies of the gut or linked to nutritional or metabolic disorders among which severe acute malnutrition are causally linked to an alteration of the diversity of the human gut microbiota. In fact, it has recently been shown by several studies that the gut microbiota of malnourished patients was different and colonized by Proteobacteria, Enterococci, Gram-negative bacilli and pathogenic species. The analysis of our data regarding the fecal microbiota of children afflicted with severe acute malnutrition from Niger and Senegal showed a dysbiosis observed through metagenomics and culturomics with an increase of aerobic bacteria, Proteobacteria and pathogenic species such as Streptococcus gallolyticus, and a depletion of anaerobic species associated with a loss of the antioxidant capacity of the gastro-intestinal tract exhibited by a total absence of Methanobrevibacter smithii, a methanogenic archaeon and one the most oxygen sensitive prokaryote of the gut microbiota alongside an increased fecal redox potential. Moreover, a loss of the overall diversity, known and unknown, was observed. Finally, through culturomics and metagenomics, we were able to identify a repertoire of missing microbes in malnourished children among which thirteen presented a probiotic potential and will be tested as such in an experimental model in the near future.

Twenty Sierra Leonean rural illiterate mothers were querried about their perceptions of the factors related to Kwashiorkor. Demographic data was hand tabulated to determine the frequency of parents' occupations, pregnancies, live and stillbirths, living and dead children, and causes of children's deaths. Chi-square analyses were done to assess the distribution of responses to questions about 19 beliefs which the researcher thought were related to Kwashiorkor. Student t-test was used to determine the differences in the total number and outcome of pregnancies between women who agreed and disagreed about the role of four of the factors which tended to show or showed significance with chi-square analyses.The families were subsistence farmers. In addition, 65 percent or the husbands had other jobs. Combined, the 20 women had 191 pregnancies, 166 live births, (87 percent of pregnancies), 25 (13 percent) stillbirths, 82 living children (43 percent of pregnancies and 49 percent of live births). The women lost through death 84 (50.6 percent) of the 166 live born children.The average woman experienced 9.6 pregnancies, resulting in 8.3 live births, and 1.3 stillbirths, had an average of 4.1 living children and had lost an average of 4.2 live born children. The data indicated that the major problem with infant/child mortality occurred after birth. Protein-Energy Malnutrition accounted for 38.1 percent of the children's deaths.Of the 19 factors about which women were querried in relation to role in Kwashiorkor, to only 4, namely “Witchcraft,” “Religious beliefs,” “Grandmother's advice,” and “Mother-in-law's advice” did less than half of the women agree. The majority of women agreed that 15 of the factors were associated with Kwashiorkor.That indicated the women had supportable understanding of factors truly related to Kwashiorkor.Three constructs, beliefs about “Witchcraft,” “Introduction of other foods,” and “Immunizations,” differentiated incidence and outcome of pregnancy among women. However, belief about the importance of “Immunizations” differentiated infant/child mortality and will be most useful in future research to analyze differences and to identify groups at greatest risk of child mortality.Ball State UniversityMuncie, IN 47306