Currently, as one of the most popular technologies being discussed and experimented, the application of flying copters in different industries is facing an obvious barrier; which is how to avoid obstacles while flying. One of the industries among all is small-sized package delivery business, which is also the master topic of a series of experiments. The most popular designs that have used for the Flying Copter Obstacle Avoidance System such as lidar scanners and infrared rangefinders are significantly accurate. However, with the heavyweight, expensive price and higher power consumption, these systems cannot be put into mass production. To reduce the cost and power consumption of the Obstacle Avoidance System, an innovative vision-based low-cost Obstacle Distance Estimation System for flying copters is demonstrated in this thesis. The Fisheye Lens Camera is used to provide a broader detection range and accurate results. Compared to other standard vision-based systems, the Fish Lens Camera Distance Estimation System can provide (around 360 degrees) extensive view for obstacle detection. Through the parallax pictures captured by the camera and the trigonometric rules, the system can estimate the distance to the target obstacle with reasonable results.

Indiana University-Purdue University Indianapolis (IUPUI) / Cell shape changes and signaling pathways are essential for the development and function of the lens. During lens development proliferating epithelial cells will migrate down to the equator of the lens, differentiate into lens fiber cells, and begin to elongate along the lens capsule. The Fibroblast Growth Factor (FGF) signaling pathway has been extensively studied for its role in lens fiber cell differentiation and elongation. However, the main mediators of FGF stimulated lens fiber cell elongation have not been identified. Adaptor proteins Crk and CrkL are SH2- and SH3-containing proteins that transduce signals from upstream tyrosine phosphorylated proteins to downstream effectors, including Ras, Rac1 and Rap1, which are important for cell proliferation, adhesion and migration. Underlying their diverse function, these two adaptor proteins have been implicated in receptor tyrosine kinase signaling, focal adhesion assembly, and cell shape. To explore the role of Crk and CrkL in FGF signaling-dependent lens development and fiber elongation, we employed Cre/LoxP system to generate a lens specific knockout of Crk/CrkL. This led to extracellular matrix defects, disorganization of the lens fiber cells, and a defect in lens fiber cell elongation. Deletion of Crk and CrkL in the lens also mitigated the gain-of-function phenotype caused by overexpression of FGF3, indicating an epistatic relationship between Crk/CrkL and FGF signaling during lens fiber cell elongation. Further studies, revealed that the activity of Crk and CrkL in FGF signaling is controlled by the phosphatase Shp2 and the defect observed in lens fiber cell elongation can be rescued by constitutive activation of the GTPases Ras and Rac1 in the Crk and CrkL mutant lens. Interestingly, the deletion of the GTPases Rap1 in the lens showed no obvious phenotype pertaining to lens fiber cell elongation. These findings suggest that Crk and CrkL play an important role in integrating FGF signaling and mediating lens fiber cell elongation during lens development.

京都大学 / 0048 / 新制・課程博士 / 博士(情報学) / 甲第21910号 / 情博第693号 / 新制||情||119(附属図書館) / 京都大学大学院情報学研究科知能情報学専攻 / (主査)講師 延原 章平, 教授 西野 恒, 准教授 飯山 将晃 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM

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This thesis project investigates the configuration of an enclosed evaporation chamber with the intention of converting seawater into potable freshwater. The evaporation chamber's sole heat source is provided by a Fresnel lens, located above the chamber, which concentrates sunlight onto a 3-inch diameter focal plate built into the core of the chamber. The design of the evaporation chamber is modeled after a solar still and is coupled with a heat exchanger to boost efficiency of the system. The chamber was designed with the objectives of being portable, lightweight, low cost, corrosion resistant, interchangeable, and size convenient with the goal of producing 1 Liter of freshwater per hour of operation. The evaporation chamber consists of two primary components, a core and an attached arrangement of fins, all of which are heated via the Fresnel lens. A consistent intake of 2 grams/second of saltwater enters from the top of the chamber and is then gravity fed across the fins. Fin orientation has been designed to inhibit the flow rate of water within the chamber, maximizing the surface area of contact with the heated fins. The evaporation chamber was modeled through SOLIDWORKS and underwent a physical optimization study to reduce material usage while maximizing potential for heat transfer and minimizing fluid flow rate. A symmetric profile of one quarter of the chamber was then simulated in COMSOL Multiphysics. Concentrated solar heat flux through a Fresnel lens was applied to the receiver on the top of the core. The simulation was split into a preheating and an evaporation phase. A profile approximation for the fluid flow was modeled by the CFD module. Following computer simulations, the evaporation chamber was constructed and tested.

Conventional solid-state photonic devices exhibit an ultra-high optical performance and durability, but minimal adaptability. Recently, optical fluid-based photonic and display devices are emerging. By dynamically manipulating the optical interface formed by liquids, the optical output can be reconfigured or adaptively tuned in real time. Such devices exhibit some unique characteristics that are not achievable in conventional solid-state photonic devices. Therefore, they open a gateway for new applications, such as image and signal processing, optical communication, sensing, and lab-on-a-chip, etc. Different operation principles of optical fluidbased photonic devices have been proposed, for instance fluidic pressure, electrochemistry, thermal effect, environmentally adaptive hydrogel, electro-wetting and dielectrophoresis. In this dissertation, several novel optical fluid-based photonic and display devices are demonstrated. Their working principles are described and electro-optic properties investigated. The first part involves photonic devices based on fluidic pressure. Here, we present a membrane-encapsulated liquid lens actuated by a photo-activated polymer. This approach paves a way to achieve non-mechanical driving and easy integration with other photonic devices. Next, we develop a mechanical-wetting lens for visible and short-wavelength infrared applications. Such a device concept can be extended to longer wavelength if proper liquids are employed. In the second part, we reveal some new photonic and display devices based on dielectrophoretic effects. We conceive a dielectric liquid microlens with well-shaped electrode for fixing the droplet position and lowering the operating voltage. To widen the dynamic range, we demonstrate an approach to enable focus tuning from negative to positive or vice versa in a single dielectric lens without any moving part. The possibility of fabricating microlens arrays iv with different aperture and density using a simple method is also proposed. Furthermore, the fundamental electro-optic characteristics of dielectric liquid droplets are studied from the aspects of operating voltage, frequency and droplet size. In addition to dielectric liquid lenses, we also demonstrate some new optical switches based on dielectrophoretic effect, e.g., optical switch based on voltage-stretchable liquid crystal droplet, variable aperture or position-shifting droplet. These devices work well in the visible and near infrared spectral ranges. We also extend this approach to display and show a polarizer-free and color filter-free display. Simple fabrication, low power consumption, polarization independence, relatively low operating voltage as well as reasonably fast switching time are their key features.

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