Thesis (Ph. D.)--Ohio State University, 2003. / Title from first page of PDF file. Document formatted into pages; contains xiv, 122 p.; also contains graphics. Includes abstract and vita. Advisor: Joseph, Dept. of Statistics. Includes bibliographical references (p. 119-122).

Thesis (Ph. D.)--Lehigh University, 1999. / Includes vita. Bibliography: leaves 109-112.

Thesis (Ph. D.) -- Virginia Commonwealth University, 2006. / Prepared for: Dept. of Biostatistics. Bibliography: leaves 96-101. Also available online.

Thesis (Ph.D.)--Baylor University, 2006. / Includes bibliographical references (p. 190-201).

Orientador: Eliane Heiser de Freitas Marques / Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Matematica, Estatistica e Computação Cientifica / Made available in DSpace on 2018-07-23T04:14:45Z (GMT). No. of bitstreams: 1 Baia_LusaneLeao_M.pdf: 1894820 bytes, checksum: c819ddd81bc3e730d50d63289eee9256 (MD5) Previous issue date: 1997 / Resumo: A realização deste trabalho tem por finalidade apresentar aplicações práticas do método das equações de estimação generalizadas (EEG), como uma nova alternativa para análise de dados. A proposta inclui breve resumo da teoria, descreve programas computacionais existentes e apresenta análise de dois conjuntos de dados reais. A intenção é colocar ao alcance do profissional de estatistica mais uma ferramenta para análise de dados complexos, aplicando a metodologia em dois conjuntos de dados do Hospital de Clínicas (HC) da Universidade Estadual de Campinas - Unicamp. Por se tratar de um assunto que envolve uma teoria mais complexa, as EEG têm sido mais usadas e descritas em revistas científicas teóricas, dificultando o uso das mesmas por pesquisadores de outras áreas nos seus dados de pesquisa. A motivação deste trabalho foi estudar esta técnica e fazer aplicações que respondessem questões resultantes de dados levantados por profissionais de saúde brasileiros. / Abstract: The purpose of dissertation is to present some practical applications using the Generalized Estimating Equations (GEE) method as a new alternative to data analysis. This proposal includes a brief surnrnary of the theory, a description of computer programs available and an analysis of two sets of data based on actual findings colleted medical School Hospital at the Campinas State University- Unicamp. It also provides one more tool to be used by professionals in Statistics in their analysis of complex data as well as by professionals from other areas who, because ihe GEE consists of a complex theory and is mostly described scientific journals, may have difficulty in using it. It result of an attempt to answer questions presented by the Brazilian health professionals. / Mestrado / Mestre em Estatística

Introduction: The process by which children's bones grow has not been fully charcterised. The current dogma is that girls fill in their medullary canal area by forming bone at the endosteum. It has been argued that the sex difference in how bone strength is conferred -- favouring boys -- may contribute to the relative protection that aging men have over aging women with respect to fracture incidence and the prevalence of osteoporosis. Primary Objectives: 1)To compare bone surface changes at the periosteal and endosteal surface of the tibial midshaft in boys and girls. 2)To compare how bone density at the tibial midshaft is accrued in boys and girls. 3) To compare sex differences in bone strength accrual. Methods: Design and Participants: Participants were obtained from a 20-month randomized, controlled school-based physical activity intervention. As we found no difference in the effect of the intervention on pQCT bone outcome variables, both groups were combined for our current study. A total of 183 participants (93 boys, 89 girls) received a pQCT scan at baseline. Results: Sex-specific comparisons of the pQCT bone outcome variables showed significantly greater rates of change (slope) for boys for the total area (ToA), cortical area (CoA), medullary canal area (MedA) and strength-strain index (SSI) measures, p<0.001. No significant differences were observed for CoD, p=0.904. The magnitude of these differences is 60.8% for ToA, 55.7% for CoA, 75.6% for MedA, 1.3% for CoD, and 54.7% for SSI. Examination of differences between the sexes (intercept) revealed significant differences with greater gains observed for boys for all measures p<0.001 except for CoD where girls exhibited greater gains p<0.001. Conclusion: Girls showed a similar pattern of cortical bone growth at the tibial midshaft- periosteal apposition dominated over endosteal resorption. Boys' increased changes and pattern of growth were of a greater magnitude at both surfaces compared to girls. This resulted in a greater increase in strength as measured by SSI in boys which can partly be explained by their larger size. Girls exhibited greater increases in CoD; however, no significant difference in the change in CoD was observed between the two. / Medicine, Faculty of / Medicine, Department of / Experimental Medicine, Division of / Graduate

Yes / Objectives: We aimed to examine change over time in self-rated quality of life (QoL) in people with mild-to-moderate dementia and identify sub-groups with distinct QoL trajectories. Method: We used data from people with mild-to-moderate dementia followed up at 12 and 24 months in the IDEAL cohort study (baseline n=1537). A latent growth model approach examined mean change over time in QoL, assessed with the QoL-AD scale, and investigated associations of baseline demographic, cognitive and psychological covariates with the intercept and slope of QoL. We employed growth mixture modelling to identify multiple growth trajectories. Results: Overall mean QoL scores were stable and no associations with change over time were observed. Four classes of QoL trajectories were identified: two with higher baseline QoL scores, labelled Stable (74.9%) and Declining (7.6%), and two with lower baseline QoL scores, labelled Stable Lower (13.7%) and Improving (3.8%). The Declining class had higher baseline levels of depression and loneliness, and lower levels of self-esteem and optimism, than the Stable class. The Stable Lower class was characterised by disadvantage related to social structure, poor physical health, functional disability, and low psychological well-being The Improving class was similar to the Stable Lower class but had lower cognitive test scores. Discussion: Understanding individual trajectories can contribute to personalised care planning. Efforts to prevent decline in perceived QoL should primarily target psychological well-being. Efforts to improve QoL for those with poorer QoL should additionally address functional impairment, isolation, and disadvantage related to social structure. / This work was supported by Economic and Social Research Council (ESRC, part of UK Research and Innovation, UKRI) and National Institute for Health Research (NIHR) grant ES/L001853/2. Alzheimer‟s Society Centre of Excellence grant 348, ASPR2-16-001

No description available.

published_or_final_version / Education / Master / Master of Education

Made available in DSpace on 2014-06-11T19:31:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-02-06Bitstream added on 2014-06-13T19:40:47Z : No. of bitstreams: 1 borsatto_ea_dr_jabo.pdf: 557549 bytes, checksum: 1b07b6fc386cbfbab60d13009c510e7f (MD5) / Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) / O trabalho teve como objetivo a análise operacional de uma semeadora– adubadora, avaliando-se a influência da pressão de inflação do pneu acionador da semeadora na cultura do milho (Zea mays L.), em sistema de plantio direto, em três tipos de manejo. O experimento foi implantado em área do Laboratório de Máquinas e Mecanização Agrícola do Departamento de Engenharia Rural - Unesp/Jaboticabal, em Latossolo Vermelho eutroférrico. O experimento foi composto por três sistemas de manejo da cultura do sorgo; combinados com três pressões de inflação do pneu de acionamento dos mecanismos dosadores da semeadora-adubadora em esquema fatorial 3 x 3 com 4 repetições. Os manejos utilizados foram: Controle Químico (dessecação); Controle Químico mais Controle Mecânico (Triturador de Palhas) e Controle Químico mais Controle Mecânico (Rolo Faca). Foram avaliados para caracterização da área experimental os parâmetros: porcentagem de cobertura vegetal no solo, massa seca da cobertura vegetal e resistência mecânica do solo a penetração. Para caracterização das plantas foram analisados: número de dias para emergência, população inicial e final, distribuição longitudinal, altura de inserção da espiga viável e produtividade. Para caracterização de desempenho do conjunto trator-semeadora-adubadora foram avaliados: força de tração, velocidade de real deslocamento, eficiência de deslocamento, potência, capacidade de campo operacional, tempo efetivo, consumo de energia, consumo horário, consumo operacional, consumo ponderal, consumo especifico, patinagem do trator e patinagem da semeadora. Os resultados indicam que a pressão do pneu da semeadora afetou a força de tração, potência, potência de pico, velocidade real de deslocamento, eficiência de deslocamento, capacidade de campo operacional, tempo efetivo, consumo de energia médio, consumo horário e o consumo ponderal. / The work had for objective the operational analysis of a seeder-fertilizer, evaluating the influence of the tire inflation pressure of the trigger seed in maize (Zea mays L.) in no till system in three types of management . The experiment was located in an area of the Laboratory of Agricultural Machinery and Mechanization Department of Rural Engineering - Unesp / Jaboticabal in Oxisol. The experiment was composed of three management systems of the culture of sorghum, combined with three of the tire inflation pressures of drive mechanisms doser of seeder-fertilizer in a factorial 3 x 3 with 4 replications. The managements were: Chemical Control (desiccation); Mechanical Control Chemical Control more (Grinder of straw) and more control Chemical Control Mechanical (Roll Knife). Were evaluated for characterization of the Experimental parameters: percentage of vegetation cover in soil, dry mass of vegetation cover and soil mechanical resistance to penetration. For characterization of the plants were analyzed: number of days to emergence, initial and final population, longitudinal distribution, time of insertion of the spike viable and productivity. To characterize the performance of all tractor-seeder-fertilizer were evaluated: the force of traction, speed of displacement, the displacement efficiency, power, capacity of the operational field, effective time, energy consumption, time consumption, consumption operational, mass consumption, specific consumption, skating rink of the tractor and seeder. The results indicate that the tire pressure of the seed affect the force of traction, power, peak power, real speed of displacement, the displacement efficiency, field capacity operational, effective time, average power consumption, time consumption and the consumption weight.