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11	Studium buněčné toxicity vybraných nanočástic v tkáňových kulturách. / Study of Cellular Toxicity of Representative Nanoparticles in Tissue Cultures. Filipová, Marcela January 2020 (has links) Safety concerns arising from cytotoxic behavior of nanoparticles (NPs) in complex biological environment remain the main problem limiting NPs application in biomedicine. In this study, we have investigated cytotoxicity of NPs with different composition, shape and size, namely SiO2 NPs (SiNPs, 7-14 nm), superparamagnetic iron oxide NPs (SPIONs, 8 nm) and carboxylated multiwalled carbon nanotubes (CNTCOOHs, diameter: 60-100 nm, length: 1-2 μm). Cytotoxicity was evaluated with newly designed screening assay capable to simultaneously assess activity of cell dehydrogenases, activity of lactate dehydrogenase (LDH) released from cells into environment and number of intact cell nuclei and apoptotic bodies in human umbilical vein endothelial cell (HUVEC) culture growing in the very same well of the 96-well plate. Aforementioned attributes were subsequently utilized to obtain information about cell viability and necrotic and apoptotic aspects of cell death. Results from this "three-in-one" cell death screening (CDS) assay showed that SiNPs and CNTCOOHs evoked pronounced cytotoxic effect demonstrated as decrease of cell viability and development of apoptotic bodies formation. In contrast to this, SPIONs induced only mild cytotoxicity. Moreover, SiNPs impaired cell membrane leading to increased LDH release...
12	Kleinskalige Magnetfelder der Sonne und ihr Einfluß auf Chromosphäre, Übergangszone und Korona / Small-Scale Solar Magnetic Fields and their Influence upon Chromosphere, Transition Region and Corona Wilken, Volker 28 June 2001 (has links) No description available. 530 Physik Mathematics and Computer Science GCT VTT SUMER SOHO UV/EUV-Teleskop Spektroskopie Polarimetrie seeing Sonne Magnetfeld chromosphärisches Netzwerk Photosphäre Chromosphäre Übergangszone Korona explosive Ereignisse magnetische Flußröhren magnetische Strukturen zweidimensionale Spektropolarimetrie GCT VTT SUMER SOHO UV/EUV Telescope spectroscopy polarimetry seeing sun magnetic field chromospheric network photosphere chromosphere transition region corona explosive events magnetic flux tubes magnetic structures two-dimensional spectro-polarimetry 39.51 TGC 100: Sonnenbeobachtung {Astronomie} TGC 300: Sonnenspektrum {Astronomie} TGC 500: Sonnenaktivität {Astronomie} TGC 740: Sonnenatmosphäre RPV 200: Optische Instrumente {Physik} RPV 260: Fernrohr Teleskop {Physik: Optik} RPV 340: Filter {Physik: Optik} RR 000: Spektroskopie {Physik} TCG 000: Astronomische Optik

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Studium buněčné toxicity vybraných nanočástic v tkáňových kulturách. / Study of Cellular Toxicity of Representative Nanoparticles in Tissue Cultures.

Kleinskalige Magnetfelder der Sonne und ihr Einfluß auf Chromosphäre, Übergangszone und Korona / Small-Scale Solar Magnetic Fields and their Influence upon Chromosphere, Transition Region and Corona