The fatigue of materials and structures is a phenomenon in which surface condition plays an important role; specially in initiating the micro-cracks. Moreover, the structural components are also subjected to aggressive environments and hence are susceptible to corrosion phenomenon. Therefore, it is necessary to protect them against the corrosion phenomenon. For aluminium alloys used in aeronautical applications, anodization is widely used surface treatment to increase the corrosion resistance. Despite the benefits obtained in terms of enhanced corrosion resistance, the anodizing process has a damaging effect on the fatigue performance of the base material. One of the reasons for this decrease in fatigue life is associated to the degradation of surface condition during the anodizing process. In this work, we have studied the influence of machining and anodization on fatigue behaviour of aluminium alloys 2214 and 7050. We showed experimentally that for 2214 alloy the process of anodization-sealing reduced the fatigue life considerably while for 7050 alloy the process of pickling is the major cause in decreasing the fatigue life. We have also developed life prediction model for anodized alloys. The model is based on determination of concentration of stress ‘Kt’ generated by the surface condition. The developed model integrates the aspects of multi-site initiation, coalescence and regime of short crack propagation.