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The purpose of this study was to determine if the Atkins diet had an effect on resting metabolic rate. In addition, the study will further explore the effects of the Atkins diet on blood lipids (total cholesterol, low-density lipoprotein, high-density lipoprotein, triglycerides) and glucose as well as body composition. Eighteen healthy women (mean age 42.4 ± 7.4 yrs, mean BMI 33.7± 5.6 kg' m -2) participated in the 6-week diet intervention. Pre- testing and post-testing included collection of: fasting blood lipids, resting metabolic rate and body composition data measured by air displacement plethysmography. Statistical analysis used to compare baseline and post study data included dependant t-tests. A significant decrease from baseline was noted in resting metabolic rate (1518 to 1374 kcals' day -1). Decreases in body mass (91.0 ± 4.0 to 86.6 ± 3.9 kg), fat mass (42.3 ± 3.1 to 38.0 ± 3.1 kg, and BMI (33.7 ± 1.3 to 32.1 ±1.3 kg' m "2) were noted but there was no significant change in fat-free mass (48.6 ± 1.3 to 48.6 ±1.1 kg). The only significant finding from the blood lipid profile was a decrease in triglyceride levels (121 ± 17.9 to 98 ±12.7 mg ' dL-1). In conclusion, this study showed that adherence to the Atkins diet for six weeks did improve body composition; decrease triglycerides and decrease resting metabolic rate. / School of Physical Education, Sport, and Exercise Science

Thesis (M.F.C.S.)--Bowling Green State University, 2005. / Document formatted into pages; contains vii, 68 p. Includes bibliographical references.

Thesis (M.S.)--Ohio University, March, 2006. / Title from PDF t.p. Includes bibliographical references (p. 67-75)

The effects of maternal dietary glucose restriction on reproductive performance were investigated by feeding pregnant rats isocaloric diets containing graded levels of dietary glucose (0, 12, 24 and 60%) during pregnancy and during pregnancy and lactation, and by measuring the effects of glucose restriction on (1) maternal, fetal and neonatal metabolism, on (2) growth and composition of the mammary glands and placentas, and (3) on milk composition. Carbohydrate restriction induced maternal metabolic adaptations that were proportional to the severity of the glucose restriction. Placental growth and composition as well as mammary gland composition were not affected by dietary glucose restriction, whereas fetal growth and development and milk composition were significantly impaired when glucose was limited in the maternal diet. This suggests that the effects of dietary glucose on the fetus and on milk composition were not mediated by changes in placenta and mammary gland DNA, protein or glycogen concentrations. Complete dietary glucose restriction significantly depressed fetal liver, lung and heart glycogen concentrations; repletion of the maternal diets with 12 and 24% glucose restored cardiac glycogen to normal but not fetal lung glycogen and liver glycogen. Pups born to dams fed a glucose-free diet failed to survive longer than 24 h postpartum and that was associated with the low levels of tissue glycogen at birth in these pups. At birth, lung and liver glycogen concentration of pups of the 12 and 24% glucose diets was similar to pups of the control diet despite the fact that these reserves were depressed in utero; and these pups efficiently corrected the transient hypoglycemia observed following parturition. The effects of glucose restriction on fetal liver glycogen were not reflected by similar changes in fetal plasma insulin, glucagon and glucose levels or in glycogen synthase and phosphorylase activities. Maternal dietary glucose was an important determinant

Thirty-seven overweight/obese (BMI: 25-35 kg/m2), premenopausal women that were randomly assigned to either an ad libitum low-carbohydrate (LC) (20% CHO, 30-40% protein, 30-40% fat), or an ad libitum low-fat (LF) (55-60% CHO, 15-20% protein, 20-25% fat) diet.All subjects were given weekly menus matching their assigned macronutrient requirements to aid in meal planning and dietary compliance. Baseline and post-diet measures included height, weight, body composition (DXA), blood lipids [total cholesterol (TC), HDL, LDL, and triglycerides (TG)], and plasma insulin levels. There were no significant group differences in any of the above-listed variables prior to the study. Nineteen women completed the 6-wk study (LC=11, LF=8). Compliance to the diets was adequate as indicated by weekly 24-hr recalls and daily urinary ketone levels. Both groups lost a significant amount of weight and body flat, (P<0.05); and weight and body fat losses were not significantly different between the groups. All groups experienced similar decreases in TG, TC, LDL, HDL, and insulin levels. These results indicate a LC diet is no more effective than a LF diet in promoting favorable changes in body weight, body composition, blood lipids and insulin levels. / Department of Family and Consumer Sciences

No description available.

Sammanfattning   Bakgrund: Övervikt och fetma har blivit en hälsofarlig nödsituation i västvärlden, i synnerhet bukfetma som är en av de viktigaste riskfaktorerna för kardiovaskulära sjukdomar. Den västerländska dieten domineras av högt förädlade livsmedel till låg kostnad vilket snabbt har utvecklat övervikt och överviktsrelaterade sjukdomar. Det finns olika behandlingsmetoder för att minska övervikt och fetma, där kost är en viktig komponent. Lågkolhydratkost kommer alltmer i fokus, som ett alternativ till de rådande näringsrekommendationerna. För att stödja och motivera personer med övervikt och fetma kan sjuksköterskan förmedla en personcentrerad egenvård enligt Orem. Sjuksköterskan skall enligt lag arbeta evidensbaserat och det krävs ständig uppdatering av forskningsläget. Syfte: Syftet var att studera effekten av lågkolhydratkost hos personer med övervikt och fetma. Metod: Litteraturöversikten är av kvantitativ metod och innehåller 15 vetenskapliga artiklar. Analysmodellen som användes var Fribergs analys. Resultat: Effekter av lågkolhydratkost visar signifikanta förbättringar i framförallt viktnedgång men även i blodtryck, blodfetter och blodsocker. De största effekterna av de olika variablerna sågs efter sex månader. Dessa effekter gav ofta en minskad användning av antidiabetika som följd. Slutsats: Då lågkolhydratkost har gynnsamma effekter på viktnedgång, blodfetter och blodsocker är behovet stort av långtidsstudier. Sjuksköterskan har en viktig roll att stödja och motivera personer med övervikt och fetma till livsstilsförändringar. Nyckelord: Viktnedgång, ketogen kost, lågkolhydratkost, egenvård / Summary Low-carbohydrate diets for overweight and obesity - A literature review   Background: Overweight and obesity has become a health hazard emergency in the western world, especially abdominal obesity which is one of the major risk factors for cardiovascular diseases. The Western diet is dominated by highly processed food at low cost, which has rapidly developed obesity and obesity related diseases. There are various treatment methods to reduce overweight and obesity by diet which is an important component. Low-carbohydrate diet comes increasingly into focus, as an alternative to the current nutritional recommendations. To support and motivate people with overweight and obesity, the nurse can convey a person-centered self-care according to Orem. The nurse should, by law, set their work based on evidence and that requires a continuous update of available research. Objective: The objective was to study the effect of low-carbohydrate diet in people with overweight and obesity. Method: The literature review is the quantitative method and contains 15 scientific articles. The analysis model used was Friberg analysis. an important role to support and motivate people with overweight Result: Effects of low-carbohydrate show significant improvements especially in weight loss but also in blood pressure, blood fats and blood sugar. The main effects of the different variables were observed after six months. These effects often gave a reduced use of antidiabetic drugs as a result. Conclusion: Since low-carbohydrate proven to have beneficial effects on weight loss, blood fat and blood sugar there is a great need for long-term studies. The nurse has and obesity to lifestyle changes. Keywords: Weight loss, ketogenic diet, low-carbohydrate diet, self-care

acase@tulane.edu

Syftet med denna pilotstudie var att studera om man hos pediatriska patienter som lider av sjuklig fetma kan se förändringar i metabolismen genom att ersätta den traditionella kosten med en kost bestående av hög andel fett och låg andel kolhydrater. De frågeställningar som används är om den förändrade kosten leder till en gynnsam förändring av metabola markörer samt hur patientupplevelsen av de nya kostråden är. Studien har både en kvantitativ och kvalitativ design. Totalt ingår 4 barn i åldern 4-17 år. Två av dessa har under fyra veckor ätit en kost bestående av hög andel fett (50-60E%) och låg andel kolhydrater (15-20E%). Efter avslutad intervention undersöktes hur metabola parametrar förändrats (blodprov) samt hur patienterna upplevt kosten (frågeformulär). Resultatet visar på att kostråden leder till en sänkning av triglycerider, glukos, HDL, total kolesterol och ASAT. Bland kontrollpatienterna ser man en ökning av triglycerider, HDL och total kolesterol. Upplevelsen av kostråden beskrivs som positiva, trots att nackdelar finns. Det finns en positiv attityd till att fortsätta med kostråden.